University of Alaüama at Birmingham (UAB), Birmingham, AL 35233 Curriculum Vitae David K.C. Cooper, MA, PhD, MD, MS, DSc(Med), FRCS, FACC, FACS, FAST, FKC Name: David K.C. Cooper Birth Date: July 27, 1939 Home Address: 413 Bailey Avenue Birth Place: London, United Kingdom Pittsburgh, PA 15211 Home Phone: 412-381-2649 Citizenship: British Permanent Residency: USA Home Fax: 412-281-4647 Business Address: University of Alabama at Birmingham (UAB) Xenotransplantation Program Department of Surgery 701 19th Street South, LHRB 752 Birmingham, AL 35233, USA Business Phone: 205-996-7772 Business Fax: 205-934-8344 Email: [email protected] EDUCATION AND TRAINING UNDERGRADUATE: Dates Attended Name/Location of Institution Degree Received (Year) 1957-1963 Guy’s Hospital Medical School MB, BS (1963) University of London (Bachelor of Medicine, London, United Kingdom Bachelor of Surgery) Royal College of Physicians of London Licentiate (1963) London, United Kingdom Royal College of Surgeons of England Member (1963) London, United Kingdom GRADUATE: Dates Attended Name/Location of Institution Degree Received (Year) 1964-1971 Royal College of Surgeons of England Fellow (FRCS) (1972) London, United Kingdom University of Cambridge Master of Arts (1972) Cambridge, United Kingdom 1967-1973 Institute of Cardiology Doctor of Philosophy National Heart Hospital (1974) University of London, London, United Kingdom (by dissertation: Studies on resuscitation and short-term preservation of the canine heart) 1974-1978 Royal College of Surgeons of England Certificate of Completion London, United Kingdom of Higher Training in Thoracic Surgery (1978) University of London Doctor of Medicine (1986) London, United Kingdom (by dissertation: Clinical orthotopic and heterotopic heart transplantation: aspects of the University of Cape Town experience) Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 2 - EDUCATION AND TRAINING (Cont) GRADUATE (Cont) Dates Attended Name/Location of Institution Degree Received (Year) University of London Master of Surgery (1996) London, United Kingdon (by dissertation: Modulation of the immune response to cardiac allografts and xenografts in the baboon, with special reference to donor- recipient ABO-incompatibility) University of London Doctor of Science London, United Kingdom (Medicine) (2002) (Glycobiological, immunological and non- immunological aspects of xenotransplantation. A collection of 219 publications and patents) POSTGRADUATE: Dates Attended Name/Location of Institution Program Director/Discipline 1963-1965 Guy’s Hospital Internships London, United Kingdom (Internal Medicine: 6 months General Surgery: 6 months Cardiothoracic Surgery: 6 months) 1966-1967 Addenbrooke’s Hospital Mr. Alan Murley Cambridge, United Kingdom Senior House Officer (Junior Resident) (Accident, Orthopedic and Neurosurgical services) 1970-1971 Addenbrooke’s Hospital Sir Roy Calne Cambridge, United Kingdom Registrar (Resident) (General, Orthopedic and Urological Surgery) 1973-1974 Papworth Hospital Sir Terence English Cambridge, United Kingdom Registrar (Resident) (Cardio- thoracic Surgery) Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 3 - EDUCATION AND TRAINING (Cont) POSTGRADUATE (Cont): Dates Attended Name/Location of Institution Program Director/Discipline 1974-1977 Middlesex Hospital/ Professor Hugh Bentall Hammersmith Hospital/ Senior Registrar (Senior /Chief Harefield Hospital/ Resident) (Cardiothoracic Surgery) Hospital for Sick Children Jada Stark, FRCS London, United Kingdom Senior Registrar (Cardiothoracic Surgery 1978-1979 Papworth Hospital Sir Terence English Cambridge, United Kingdom Senior Registrar (Senior/Chief Resident) (Cardiothoracic Surgery) Clinical & Research Fellowships Dates Attended Name/Location of Institution Program Director/Discipline 1965-1966 Peter Bent Brigham Hospital Professor Francis Moore Boston, Massachusetts Surgical Research Fellow 1967-1969 Institute of Cardiology Mr. Donald Ross National Heart Hospital Surgical Research Fellow University of London London, United Kingdom 1972-1973 Cardiothoracic Institute Mr. Donald Ross University of London British Heart Foundation Junior London, United Kingdom Surgical Research Fellow 1980 Department of Cardiac Surgery Professor Christiaan Barnard Groote Schuur Hospital Clinical & Research Fellow University of Cape Town Cardiac Transplantation Medical School Cape Town, South Africa Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 4 - APPOINTMENTS AND POSITIONS ACADEMIC: Years Inclusive Name/Location of Institution/Organization Rank/Title or Position 1965-1966 Harvard Medical School Lecturer on Anatomy Boston, Massachusetts 1966-1970 Magdalene College Supervisor in Anatomy Cambridge, United Kingdom 1970-1980 Magdalene College Lecturer in Anatomy Cambridge, United Kingdom 1972-1980 Magdalene College Official Fellow Cambridge, United Kingdom 1973-1980 Magdalene College Director of Studies in Cambridge, United Kingdom Medical Sciences 1975 Royal Postgraduate Medical School Lecturer on Surgery University of London London, United Kingdom 1980-1987 Cardiac Surgical Research Laboratory Director University of Cape Town Medical School Cape Town, South Africa 1981-1985 Department of Cardiothoracic Surgery Senior Lecturer University of Cape Town Medical School Cape Town, South Africa 1985-1987 Department of Cardiothoracic Surgery Associate Professor University of Cape Town Medical School Cape Town, South Africa 1987-1995 Oklahoma Transplantation Institute Director of Research Baptist Medical Center and Education Oklahoma City, Oklahoma 1992-1995 Oklahoma Transplantation Institute Scientist-in-Residence Baptist Medical Center Oklahoma City, Oklahoma Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 5 - APPOINTMENTS AND POSITIONS (Cont) ACADEMIC (Cont): Years Inclusive Name/Location of Institution/Organization Rank/Title or Position 1996-1997 Harvard Medical School Lecturer on Surgery Boston, Massachusetts 1998-2004 Harvard Medical School Associate Professor, Boston, Massacushetts Surgery (Immunology) 2000-2004 Leverett House Non-resident Harvard College Premedical Tutor Cambridge, Massachusetts 2004-2005 Thomas E. Starzl Transplantation Institute Visiting Professor of University of Pittsburgh Surgery School of Medicine Pittsburgh, Pennsylvania 2006-2016 Thomas E. Starzl Transplantation Institute Professor of Surgery University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania 2016-present Xenotransplantation Program Co-Director and Department of Surgery Professor of Surgery University of Alabama at Birmingham (UAB) Birmingham, Alabama NON-ACADEMIC: Years Inclusive Name/Location of Institution/Organization Rank/Title or Position 1981-1985 Groote Schuur Hospital and the Red Cross Specialist in Cardio- War Memorial Children's Hospital thoracic Surgery Cape Town, South Africa 1985-1987 Groote Schuur Hospital and the Red Cross Senior Specialist in War Memorial Children's Hospital Cardiothoracic Surgery Cape Town, South Africa 1987-1995 Oklahoma Transplantation Institute Cardiothoracic Baptist Medical Center Transplant Surgeon Oklahoma City, Oklahoma Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 6 - APPOINTMENTS AND POSITIONS (Cont) NON-ACADEMIC (Cont): 1987-1995 Transplantation Research Laboratory Director Oklahoma Transplantation Institute Baptist Medical Center Oklahoma City, Oklahoma Years Inclusive Name/Location of Institution/Organization Rank/Title or Position 1988-1996 Oklahoma Medical Research Foundation Associate Member, Oklahoma City, Oklahoma Scientific Staff 1991-1992 Oklahoma Organ Sharing Network Medical Director Oklahoma City, Oklahoma 1996-2004 Transplantation Biology Research Center Immunologist (Surgery) Massachusetts General Hospital Boston, Massachusetts 1996 Novartis Pharmaceuticals Corporation Consultant East Hanover, New Jersey 1996-2000 Bio Transplant, Inc. Consultant Charlestown, Massachusetts 2001-2004 Immerge Biotherapeutics, Inc. Consultant Charlestown, Massachusetts 2004-2011 Revivicor, Inc. Chairman, Scientific Blacksburg, Virginia Advisory Board 2013-2016 International Conference on Scientific Advisory Clinical Islet Xenotransplantation (ICCIX) Committee CERTIFICATION AND LICENSURE SPECIALTY CERTIFICATION: Certifying Board Year Fellowship, Royal College of Surgeons of England, United Kingdom 1972 Certificate of Completion of Higher Training in Thoracic Surgery 1978 Royal College of Surgeons of England, United Kingdom Curriculum Vitae David K.C. Cooper, M.D., Ph.D. Revised: 06/05/19 - 7 - MEDICAL OR OTHER PROFESSIONAL LICENSURE: Licensing Board/State Year General Medical Council (United Kingdom) 1964-Present South African Medical & Dental Council 1980-2003 Registration as Specialist Thoracic Surgeon (South Africa) 1981-2003 Oaklahoma State Board of Medical Examiners (USA) 1985-Present MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC SOCIETIES Organization Year Royal Society of Medicine (Fellow), United Kingdom 1969-1982 Royal College of Surgeons of England (Fellow) 1971-Present British Transplantation Society (Founding Member) 1972-2011 United Kingdom Society of Cardiothoracic Surgeons of Great Britain & Ireland 1974-Present Junior Cardiac Club, United Kingdom 1974-1980 Harlech Club (Cardiothoracic Surgical Traveling Club) 1974-1991 United Kingdom Thoracic Society, United Kingdom 1978-1982 British Association of Clinical Anatomists (Fellow) 1978-1991 Southern African Cardiac Society 1980-1992 South African Association of Laboratory Animal Science 1980-1987 Southern