ARFGAP3 Antibody Cat. No.: 23-461 ARFGAP3 Antibody Immunohistochemistry of paraffin- embedded mouse stomach using Immunohistochemistry of paraffin-embedded human liver cancer using ARFGAP3 ARFGAP3 antibody (23-461) at antibody (23-461) at dilution of 1:100 (40x lens). dilution of 1:100 (40x lens). Immunohistochemistry of paraffin- embedded human esophagus using ARFGAP3 antibody (23-461) at dilution of 1:100 (40x lens). Specifications October 1, 2021 1 https://www.prosci-inc.com/arfgap3-antibody-23-461.html HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse Recombinant fusion protein containing a sequence corresponding to amino acids 217-516 IMMUNOGEN: of human ARFGAP3 (NP_055385.3). TESTED APPLICATIONS: IHC, WB WB: ,1:500 - 1:2000 APPLICATIONS: IHC: ,1:50 - 1:100 POSITIVE CONTROL: 1) HepG2 2) Mouse pancreas PREDICTED MOLECULAR Observed: 57kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: ARFGAP3 ARFGAP3, ADP-ribosylation factor GTPase activating protein 3, ARFGAP1, RP1-47A17.3, ALTERNATE NAMES: ADP-ribosylation factor GTPase activating protein 1, OTTHUMP00000028526 GENE ID: 26286 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. BACKGROUND: Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. October 1, 2021 2 https://www.prosci-inc.com/arfgap3-antibody-23-461.html ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. October 1, 2021 3 https://www.prosci-inc.com/arfgap3-antibody-23-461.html.