University of Kentucky UKnowledge Pharmaceutical Sciences Faculty Patents Pharmaceutical Sciences 10-20-1998 Chimeric Isoprenoid Synthases and Uses Thereof Joseph Chappell University of Kentucky, [email protected] Kyoungwhan Back University of Kentucky Right click to open a feedback form in a new tab to let us know how this document benefits oy u. Follow this and additional works at: https://uknowledge.uky.edu/ps_patents Part of the Pharmacy and Pharmaceutical Sciences Commons Recommended Citation Chappell, Joseph and Back, Kyoungwhan, "Chimeric Isoprenoid Synthases and Uses Thereof" (1998). Pharmaceutical Sciences Faculty Patents. 101. https://uknowledge.uky.edu/ps_patents/101 This Patent is brought to you for free and open access by the Pharmaceutical Sciences at UKnowledge. It has been accepted for inclusion in Pharmaceutical Sciences Faculty Patents by an authorized administrator of UKnowledge. For more information, please contact [email protected]. US005 824774A United States Patent [19] [11] Patent Number: 5,824,774 Chappell et al. [45] Date of Patent: Oct. 20, 1998 [54] CHIMERIC ISOPRENOID SYNTHASES AND Chappell et al., “Accumulation of Capsidiol in Tobacco Cell USES THEREOF Cultures Treated With Fungal Elicitor,” Phytochemistry 26:2259—2260 (1987). [75] Inventors: Joseph Chappell; Kyoungwhan Back, Chappell, “Biochemistry and Molecular Biology of the both of Lexington, Ky. Isoprenoid Biosynthetic PathWay in Plants,” Annu. Rev. Plant Physiol. Plant Mol. Biol. 46:521—547 (1995). [73] Assignee: Board of Trustees of the University of Chappell et al., “Is the Reaction Catalyzed by Kentucky, Lexington, Ky. 3—Hydroxy—3—Methylglutaryl Coenzyme A Reductase a Rate—Limiting Step for Isoprenoid Biosynthesis in Plants,” [21] Appl. No.: 631,341 Plant Physiol. 109:1337—1343 (1995). [22] Filed: Apr. 12, 1996 Chappell, “The Biochemistry and Molecular Biology of Isoprenoid Metabolism,” Plant Physiol. 107:1—6 (1995). [51] Int. 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