springer.com/booksellers Springer News 7/2009 Life Sciences 81 D. Armstrong, University at Buffalo, NY, USA (Ed.) D. Armstrong, University at Buffalo, NY, USA (Ed.) D. J. Clarke, University of Minnesota Medical School, Minneapolis, MN, USA (Ed.) Lipidomics Lipidomics Volume 1: Methods and Protocols Volume 2: Methods and Protocols DNA Topoisomerases Methods and Protocols In Lipidomics: Methods and Protocols, an inter- In Lipidomics: Methods and Protocols, an inter- national panel of experts present a wide variety of national panel of experts present a wide variety of In DNA Topoisomerases: Methods and Proto- reviewed as well as unpublished data on isolation reviewed as well as unpublished data on isolation cols, experts in the field present a compendium techniques, structural analysis, lipid rafts, lipid techniques, structural analysis, lipid rafts, lipid of protocols that extends into the new areas of trafficking and profiling, biomarkers, lipid peroxi- trafficking and profiling, biomarkers, lipid peroxi- research that have been recently uncovered in dation, biostatistics applied to lipids, software dation, biostatistics applied to lipids, software order to elucidate the methodology needed to tools, and bioinformatics. These studies range tools, and bioinformatics. These studies range study topoisomerases in the molecular and cellular from simple systems, such as in yeast, to complex from simple systems, such as in yeast, to complex context. The volume examines subjects such as biological models. Samples used in these studies biological models. Samples used in these studies the analysis of DNA topologies and the interac- include: mitochondria, microsomes, endosomal include: mitochondria, microsomes, endosomal tion of topoisomerases with DNA as tools to membranes, RBS and plasma membranes, vesicles, membranes, RBS and plasma membranes, vesicles, measure topoisomerase functions, the binding of caveolae, liposomes, macrophages, meibum, brain, caveolae, liposomes, macrophages, meibum, brain, topoisomerases to specific sites in the genomes of microglia, retina, adipose tissue, keratinocytes, microglia, retina, adipose tissue, keratinocytes, eukaryotes, including origins of DNA replication, pulmonary surfactant, and hepatic cultures. pulmonary surfactant, and hepatic cultures. as well as exploration of perturbed topoisomerase Written in the highly successful Methods in Written in the highly successful Methods in function. As a volume in the highly successful Molecular Biology™ series format, the chapters Molecular Biology™ series format, the chapters Methods in Molecular Biology™ series, chapters include useful introductions to their respective include useful introductions to their respective include introductions to their respective topics, topics, lists of the necessary equipment and mate- topics, lists of the necessary equipment and mate- lists of the necessary materials and reagents, rials, step-by-step, readily reproducible laboratory rials, step-by-step, readily reproducible laboratory step-by-step, laboratory protocols, and notes on protocols, and authoritative notes on trouble- protocols, and authoritative notes on trouble- trouble-shooting and avoiding known pitfalls. shooting and avoiding common pitfalls. shooting and avoiding common pitfalls. Features Features Features 7 Provides an easily accessible reference volume 7 Regarding Volume 1 and 2: 7 Contains in- 7 Regarding Volume 1 and 2: 7 Provides for topoisomerase protocols written by leading depth guides to isolation and processing of lipid examples utilizing key model systems 7 Presents researchers in the field 7 Covers a wide range samples, probes, lipid profiling, signaling, trans- oxidized lipids obtained from in vitro and in of assays from cell-based methods and molecular port, and mapping 7 Provides examples utilizing vivo biological material, redox platforms, high analysis of topoisomerases, to biochemical and key model systems 7 Presents oxidized lipids throughput systems, microscopy and imaging, and biophysical studies 7 Presents diverse approaches obtained from in vitro and in vivo biological mate- computer simulation 7 Serves as a comprehen- to experimental design, covering model biological rial, redox platforms, high throughput systems, sive guide to technical applications 7 Explores systems including yeast and mammalian cells as microscopy and imaging, and computer simulation bioinformatics strategy and statistical models for well as cell-free systems and purified components standardization of lipids Fields of interest Fields of interest Cell Biology; Membrane Biology; Lipidology Fields of interest Human Genetics; Enzymology Cell Biology; Membrane Biology; Lipidology Target groups Target groups Molecular and cellular biologists Target groups Molecular and cellular biologists, geneticists Molecular and cellular biologists, bioinformati- Type of publication cians Type of publication Contributed volume Contributed volume Type of publication Contributed volume Springer Protocols Springer Protocols Springer Protocols Due October 2009 Due October 2009 Due September 2009 2010. Approx. 480 p. 143 illus., 4 in color. (Methods in 2010. Approx. 350 p. 110 illus., 5 in color. (Methods in 2009. Approx. 320 p. 59 illus. (Methods in Molecular Molecular Biology, Volume 579) Hardcover Molecular Biology, Volume 580) Hardcover Biology, Volume 582) Hardcover 7 € 89,95 | £81.00 7 € 89,95 | £81.00 7 € 89,95 | £81.00 7 * € (D) 96,25 | € (A) 98,95 | sFr 140,00 7 * € (D) 96,25 | € (A) 98,95 | sFr 140,00 7 * € (D) 96,25 | € (A) 98,95 | sFr 140,00 9<HTMGLH=gbdcbd>ISBN 978-1-60761-321-3 9<HTMGLH=gbdcee>ISBN 978-1-60761-324-4 9<HTMGLH=gbddji>ISBN 978-1-60761-339-8 82 Life Sciences Springer News 7/2009 springer.com/booksellers M. J. Colloff L. A. del Rio, CSIC, Granada, Spain; A. Puppo, INRA H. J. Dumont, Ghent University, Gent, Belgium de Sophia-Antipolis, Nice, France (Eds.) Dust Mites The Nile Reactive Oxygen Species in Origin, environments, limnology and Conservatively, at least 100 million people are Plant Signaling human use affected by house dust mite allergy worldwide, manifesting itself as asthma, rhinitis or atopic dermatitis. Despite the growing recognition of this Until recent years the production of reactive major public health problem, and commitment of oxygen species (ROS) was generally considered to The book discusses the Nile basin from a holistic considerable research resources, there is still no be a harmful process and a generator of oxidative point of view, giving due attention to its geological simple, effective, generally-applicable strategy for stress. But more recently this concept has been history, hydrology, climate, and the full diversity of dust mite control. The reasons for this are complex, re-evaluated and the term “oxidative signaling” subsystems such as lakes and swamps. It discusses but a contributing factor remains some important was coined (Foyer and Noctor, 2005). This means at length the biota of the basin, and derives general knowledge gaps and misconceptions regarding that ROS generation is also an important compo- conclusions on the biodiversity of the plants and aspects of biology and ecology of dust mites. nent of the signaling network of plants. Results animals that inhabit it. It also examines the effects The purpose of this book is to provide a compre- obtained during the last decade have highlighted of human interventions, mainly dam building, but hensive reference work for all readers with an that ROS are key regulators of plant metabolism, also pollution and eutrophication. It ends with involvement or interest in house dust mite research morphology and development which are also used several contributions on the natural resource value and management, incorporating for the first by plants to respond to environmental challenges. of water, and the constraints this imposes on the time in a single volume the topics of systematics The role of ROS as signals for gene expression policies of the riparian states. and identification, physiology, ecology, allergen has been established, and ROS also modulate the biochemistry and molecular biology, epidemi- activity of key signaling compounds such as MAP Features ology, mite control and allergen avoidance. kinases. The volume of research into the roles 7 Features a multidisciplinary account of the of ROS in plants is currently growing and the longest river of the world: the Nile 7 Discusses Features purpose of this book is to present recent advances the geological history, hydrology, climate, the biota 7 Many chapters contain new data, or new in this field. of the basin, the effects of human interventions analyses of existing data (including global distribu- and the value of water as a natural resource tion maps of the most important species) Features 7 This book is a new edition to the 1976 The Nile 7 Explains key biological and ecological concepts 7 Presents recent advances in the field of reactive monograph by Rzo’ska for non-specialist readers 7 Explores how char- oxygen species (ROS) in plants highlighting new acteristics of population growth, water balance and data and concepts From the contents physiology of dust mites have contributed to their Part I Origin. Part II Major Nilotic Environ- importance as allergenic organisms Fields of interest ments. Part III Climates And Hydrology. Part Plant Physiology; Plant Biochemistry; Plant IV Limnology And Biological Diversity. Part V Fields of interest Sciences Human Use. Life Sciences, general; Plant Sciences Target groups Fields of interest