Recruitment Recruitment Rec Number Name of Trial Target End Date Trial Status Target met ? 20080763 Panitumumab vs Cetuximab in 09/H0402/92 Colorectal Cancer 10 05/01/2015 Closed - Follow Up Complete Y BO21004 - RO5072759 Safety and Efficacy 09-WSE04-55 Chemo Combo in untreated CLL 5 01/04/2022 Closed - In Follow Up Y Phase 3 Study-Tivozanib in Patients with 09/H0903/51 Advanced Renal Cell Carcinoma 5 05/01/2015 Closed - Follow Up Complete N LDK378-Dose Escalation/Expansion study in 10/MRA00/84 patients with ALK+ tumour 2 31/05/2016 Closed - In Follow Up Y Phase I Study of NY-ESO-1 +AS15 in 10/H0806/106 Melanoma Version 1 4 05/01/2015 Closed - Follow Up Complete N BH21260- Mircera? vs. reference ESAs in CKD 08/H0502/133 patients (SUB STUDY) 10 01/01/2016 Withdrawn N/A R-CHOP vs G-CHOP in previously untreated 11/EM/0225 patients with DLBCL 5 01/02/2018 Closed - In Follow Up N 11/NI/0147 SJM Portico 23-TF EU 12 30/11/2014 Closed - In Follow Up Y A UK Phase IIIB expanded access study of 11/SC/0499 INC424 in myelofibrosis 3 13/07/2015 Closed - Follow Up Complete Y 11/AL/0393 Synta 9090-08 20 04/12/2014 Closed - Follow Up Complete N 12/LO/0806 Aflibercept SQoP (AFLIBC06097) 5 31/12/2015 Closed - In Follow Up Y MASERATI 100 Permacol Collagen Paste 12-LO-0928 Study 10 30/04/2015 Closed - In Follow Up Y SafeHer: Safety study with subcutaneous 12/SC/0139 Trastuzumab in breast cancer 10 23/09/2016 Open N/A Safety and tolerability of ONO-4059 in 12/EM/0204 patients with NHL & CLL 7 15/07/2015 Closed - In Follow Up Y Clinical trial of an investigational medicinal 12/NW/0242 product (CTIMP) 15 07/07/2015 Closed - In Follow Up N Study of GDC-0941 for the treatment of non- 12/NE/0009 small cell lung cancer (FIGARO) 9 28/05/2015 Closed - Follow Up Complete N ROX CONTROL HTN STUDY: Protocol RH-02 12/LO/1313 Version 1.0, June 20, 2012 20 01/01/2017 Closed - In Follow Up N STARLYTE: ARD10248 in patients with diffuse 12/EM/0206 large B cell lymphoma 2 29/03/2015 Closed - In Follow Up Y Tasquinimod in patients with advanced/ 12/NE/0333 metastatic HCC,GC,OAC and RCC 10 22/04/2015 Closed - Follow Up Complete N The Effects of Serelaxin in Coronary Artery 13/ES/0088 Disease 30 31/12/2016 Open N/A EMR 100070-001: Phase I study of 13/LO/1766 MSB0010718C in solid tumors 3 31/10/2015 Suspended N 13/EM/0476 ABSORB UK Registry V1 30 17/11/2017 Open N/A ACP-196 in subjects with Relapsed or 14/SW/1062 Refractory de Novo ABC DLBCL 17 03/03/2016 Open N/A VS-6063-104 Phase 1 study in relapsed 14/LO/1996 malignant mesothelioma 14 14/12/2016 Open N/A Long-term Access Programme for Subjects 15/EM/0077 who Participated in MEA115921 4 29/05/2020 Open Y NOX-H94 in ESA-hyporesponsive anaemia in 13/LO/1714 dialysis patients V2.0 2 15/02/2016 Open N/A AZD5363 in patients with advanced or 12/LO/0803 metastatic breast cancer (BEECH) 10 31/10/2015 Open N/A FGF117360 Clinical study using drug 13/EE/0345 GSK3052230 in Subjects with Cancer 5 30/10/2031 Open N/A 1237.16 Tiotropium + Olodaterol 14/EM/0101 (PHYSACTO[TM]) in COPD 3 26/06/2015 Closed - In Follow Up N Elagolix in Endometriosis Associated Pain 14/SC/0181 Extension Study 6 31/08/2016 Open N/A 14/EE/0076 ASSURE 6 13/07/2016 Open N/A Phase 2 Study of Fostamatinib for Subjects 14/LO/0865 with IgA Nephropathy 4 28/01/2016 Open N/A Recruitment Recruitment Rec Number Name of Trial Target End Date Trial Status Target met ? Study to evaluate safety & efficacy of 14/EM/1003 Blisibimod in IgA Nephropathy 4 14/09/2019 Open N/A GO28667 - PH III, OPEN-LABEL, IN 14/EM/0034 RELAPSED/REFRACTORY PATIENTS WITH CLL 3 15/05/2019 Open N/A 049 FIT (Fostamatinib for Immune 14/EM/1060 Thrombocytopenia) Extension Study 3 09/10/2017 Open N/A 047 FIT (Fostamatinib for Immune 14/EM/1059 Thrombocytopenia) Study 3 07/09/2015 Closed - In Follow Up N Open label, phase 3 trial comparing Mylans 14/EM/1068 Glargine with Lantus 5 30/10/2016 Open N/A 14/NW/1248 Tralokinumab in severe asthma 4 22/12/2017 Open N/A 14/EE/1001 OTO-104 in Meniere's Disease 10 31/05/2016 Open N/A 13/NW/0283 Global Leaders Study V1.0 100 01/03/2019 Open N/A Finesse vs. Pen for Bolus Insulin in T2 DM, 14/NW/0218 revision G 8 01/04/2016 Open N/A A Study of LEE011 in combination with 14/WS/0103 Fulvestrant and BYL719 or BKM120 15 03/12/2015 Open N/A PARAGON- LCZ696 vs valsartan in patients 13/LO/1328 with chronic heart failure 10 15/08/2018 Open N/A Daptomycin in paediatric patients with AHO 14/SC/1311 (infection of the bone) 1 30/12/2016 Open N/A CheckMate 238: CHECKpoint pathway and 15/SC/0054 nivoluMAb clinical Trial Evaluation 238 5 01/06/2016 Closed - In Follow Up N Daratumumab + VMP vs VMP only in newly 15/WM/0009 diagnosed multiple myeloma 3 15/11/2016 Open N/A A Phase 3 Study to Investigate the long term 15/NW/0028 safety and efficacy of ZS 10 01/12/2016 Open N/A Phase 2 Study in Mantle Cell Lymphoma ACE- 15/EM/0135 LY-004 4 15/06/2018 Open N/A A Phase 2 Veliparib plus Chemotherapy Study 14/NE/1214 in Non-Squamous NSCLC 24 01/02/2016 Open N/A 15/NW/0152 MetaPHer 5 01/11/2018 Open N/A AEGIS-I, Phase II, dose ranging study of 14/EM/0160 CSL112 in Acute MI 10 03/10/2016 Open N/A Nivolumab monotherapy in patients with 15/LO/0691 Non-Small Cell Lung Cancer 9 15/05/2021 Open N/A Moxetumomab Pasudotox in 15/LO/0288 Relapsed/Refractory Hairy Cell Leukaemia 3 06/06/2018 Open N/A MEPO PK-PD Paediatric Study in Severe 15/LO/0718 Eosinophilic Asthma 2 30/06/2016 Open N/A Phase 1b/2 Participants with Waldenstr?m 15/YH/0125 Macroglobulinemia ACE-WM-001 6 14/04/2018 Open N/A 15/LO/0545 CARAT - RTSY03 10 30/09/2018 Open N/A 14/EM/1267 LCZ696 in patients from Paradigm HF study 7 27/01/2017 Open N/A Safety and effectiveness of SAR156597 in the 15/LO/0861 treatment of IPF 4 31/08/2018 Open N/A Efficacy and safety of LX4211 added to insulin 15/NW/0319 in Type 1 Diabetes 6 31/07/2017 Open N/A Effect of Tralokinumab on airway 15/EM/0247 inflammation in asthma 2 31/10/2017 Open N/A BH21260- Mircera? vs. reference ESAs in CKD 08/H0502/132 patients 20 31/12/2019 Closed - Follow Up Complete N 09/H0605/87 TECOS 35 01/12/2014 Closed - In Follow Up Y 09/H0706/22 Aliskiren vs enalapril in chronic heart failure 5 01/01/2016 Closed - Follow Up Complete Y 09/H0406/110 LCZ696 vs enalapril in chronic heart failure 6 31/10/2015 Closed - In Follow Up Y Recruitment Recruitment Rec Number Name of Trial Target End Date Trial Status Target met ? The Effects of JNJ-28431754 on 09/H0402/101 Cardiovascular Outcomes (CANVAS Study) 18/11/2017 Closed - In Follow Up Y Neratinib after Trastuzumab in early stage 09/H0405/44 breast cancer. 10 25/04/2017 Closed - In Follow Up N An Open Label, Multicenter, randomized, phase III study to investigate the efficacy and 10/MREC00/61 safety 16 31/12/2018 Closed - In Follow Up N 10/H0808/109 EXCEL Clinical Trial 1.0 8th June 2010 25 31/12/2017 Closed - In Follow Up Y 1200.131 LUX-Head & Neck 2; Afatinib in 11/LO/0954 Squamous Cell Carcinoma 5 28/09/2015 Closed - In Follow Up N Phase III GA101 or rituximab plus chemo in 11/NW/0298 1st line indolent NHL 28/02/2022 Closed - In Follow Up Y B1871019 Phase 2 Study in Polycystic Kidney 11/AL/0327 Disease 08/12/2017 Closed - In Follow Up Y WA25204RA with CV Outcomes (Entracte 11/EM/0180 Study) 6 22/04/2016 Closed - In Follow Up N 11/WA/0309 BIAJ The IMAGINE 2 Study DRN594 6 01/03/2015 Closed - In Follow Up N 11/LO/1408 ABSORB II RANDOMIZED CONTROLLED TRIAL 10 17/05/2018 Closed - In Follow Up Y Efficacy and Safety of Lenalidomide/Dexamethasone +/- 11/EE/0291 Elotuzumab in MM 7 31/01/2018 Closed - In Follow Up N 11/SS/0054 RESPOND CRT 10 06/05/2019 Closed - In Follow Up Y Tiotropium + Olodaterol (Torracto [TM]) in 12/NW/0082 COPD 5 24/01/2015 Closed - In Follow Up Y Austri: 6-month Safety and Benefit Study of 12/SC/0035 SERETIDE in Children 4-11 years 6 19/06/2015 Closed - In Follow Up Y 12/WM/0039 InovateHF 10 31/12/2018 Open Y Saxagliptin with metformin in paediatric type 12/SC/0173 2 diabetes patients 2 02/07/2015 Closed - In Follow Up N CANTOS- CACZ885M2301 Canakinumab in 12/EM/0018 postMI patients with raised hsCRP 10 25/07/2016 Closed - In Follow Up N NCRN322 TERRAIN: MDV3100 (ASP9785) vs.