DH 248 General and Oral Pathology Spring 2014 Meeting Times: Tuesday & Thursday 10:00 - 11:50 a.m. CASA Mortuary Science Room 70 Credits: 4 credit hours Faculty: Sherri Lukes, RDH, MS, Associate Professor, Room 129 Office: 453-7289 Cell: 521-3392 E-mail: [email protected] Office Hours: Monday 1:00 p.m. - 4:00 p.m. Tuesday 1:00-4:00 Other office hours by appointment COURSE DESCRIPTION: This course has been designed to integrate oral pathology and general pathology. Students will study principles of general pathology with emphasis on the relationships to oral diseases. Pathologic physiology is included such as tissue regeneration, the inflammatory process, immunology and wound healing. Clinical appearance, etiology, location and treatment options of general system diseases is presented, along with the oral manifestations. Special attention will be placed on common pathological conditions of the oral cavity and early recognition of these conditions. DH Competencies addressed in the course: PC.1 Systematically collect analyze, and record data on the general, oral, and psychosocial health status of a variety of patients/clients using methods consistent with medico-legal principles. PC.2 Use critical decision making skills to reach conclusions about the patient’s/client’s dental hygiene needs based on all available assessment data. PC.3 Collaborate with the patient / client, and/or other health professionals, to formulate a com- prehensive dental hygiene care plan that is patient / client-centered and based on current scientific evidence. PC.4 Provide specialized treatment that includes preventive and therapeutic services designed to achieve and maintain oral health. Assist in achieving oral health goals formulated in collaboration with the patient / client. PC.5 Evaluate the effectiveness of the implemented clinical, preventive, and educational services and modify as needed. HP.3 Refer patients/clients who may have a physiologic, psychological, and/or social problem for comprehensive patient/client evaluation. Required Textbook: DeLong, L. & Burkhart, N.W. (2013). General and Oral Pathology for the Dental Hygienist. 2nd Ed. Lippincott Williams & Wilkins, Philadelphia, PA. We WILL be using the online resources that come with the text. Some resources will be posted on D2L Recommended References/Resources: Medical dictionary either in paper or online format Oral pathology web site: http://www.usc.edu/hsc/dental/opath/ Go to the Disease Index http://www.dentalmedsoft.com/SampleCases/StartupPage.htm OPERA Plus- Oral Pathology CD available for viewing in computer lab in CASA. Langlais,R., & Miller, C. (1998). Color atlas of common oral diseases. Williams & Wilkins, Baltimore, MD. Prerequisites: DH 226, DH 233 In order to pass the course, a final grade of “C” must be achieved as a course grade. If any student needs special services, please contact the course instructor or Disability Support Services (453-5738, [email protected]). Tutoring is available for this course as a group or individually within the department. Tutors are DH juniors or seniors who received either an A or B in the course. This year’s tutors are Taylor Willer, [email protected], 636-577-2443 and Jordan Brown, [email protected], 217-213-4001. COURSE OBJECTIVES: At the completion of the course, the student will be able to: 1. Explain basic pathology terms and principles including: Definitions of key pathologic terms Description of radiographic findings Elements of a complete clinical Elements of the intra/extra oral exam Steps involved in the differential diagnosis description Steps involved in the definitive diagnosis Descriptive terms for lesions 2. Describe the integration and coordination of cell functions and response to injury as related to the following: Reversible Cell Injury Irreversible Cell Injury Atrophy Hypertrophy Hyperplasia Metaplasia Dysplasia Cell Aging Cell Death Cell Necrosis 3. Explain the inflammatory process including: 5 Cardinal Signs of Inflammation Circulatory Changes Vessel Wall Changes Mediators of Inflammation Emigration of Leukocytes Phagocytosis Cells of Inflammation Chemotaxis Granulation Tissue Purulent Exudate Wound Healing Forms of Inflammation Acute Inflammation Chronic Inflammation 4. Recall and discuss the incredible role that the immune system plays in maintaining health and overcoming disease including: Natural Immunity Acquired Immunity Lymphocytes Plasma Cells Antibody Production Hypersensitivity Reactions Transplantation Blood Transfusion Rh factor Immunodeficiency Diseases Leukocytes Autoimmune Diseases Explain the etiology, clinical features and possible treatment options of the following skin lesions and autoimmune disorder skin lesions when 5. presented on a written exam or projected on a slide: Mucous Membrane Pemphigoid Lichen Planus Lichenoid Drug Reactions Erythema Multiforme Pemphigus Vulgaris Progressive Systemic Sclerosis Contact Stomatitis Lupus Erythematosus Cheilitis Glandularis Cheilitis Granulomatosa Angioedema Basal and cell carcinoma Squamous cell carcinoma Sarcoidosis Psoriasis Eczema Actinic keratosis Seborrheic Keratoses Ephelides Actinic cheilitis Urticaria Warts Nevi Angular cheilitis Describe the clinical features and significance of the following genetic and developmental diseases when presented on a written exam or 6. projected on a slide: Fetal Alcohol Syndrome Trisomy 21 Osteogenesis Imperfecta Klinefelter’s Syndrome Marfan Syndrome Cleft lip/palate Hypercholesterolemia Gingival fibromatosis Treacher Collins Syndrome Papillon-Lefevre syndrome Ehler’s Danlos Syndrome Ectodermal dysplasia Cleidocranial dysplasia Turner’s Syndrome Explain the etiology, clinical features and possible treatment options of the following abnormalities of the teeth when presented on a written 7. exam or projected on a slide: Attrition Abrasion Internal Resorption Fracture Avulsion Anodontia External Resorption Ankylosis Impacted Teeth Erosion Macrodontia Taurodontism Cleidocranial Dysplasia Disturbances in Eruption Supernumerary Roots Dentin Dysplasia Dilaceration Conscresence Microdontia Supernumerary Cusps Amelogenesis Imperfecta Supernumerary Teeth Fusion Hypercementosis Eruption Sequestrum Gemination Dentinogenesis Imperfecta Dens Invaginatus Cervical Enamel Projections Abfraction Regional odontodysplasia Ectodermal dysplasia Porphyria Rickets (hypophosphatemia) Cleidocranial dysplasia Pulpitis Fluorosis Hemolytic Anemia External resorption Tetracycline staining Gardner Syndrome Internal resorption Hypoplasia Pulp stones Indicate the etiology, location, clinical features and significance, and possible treatment of the following endocrine disorders when presented on 8. a written exam or projected on a slide: Addison’s Disease(adrenal disorders) Gigantism Acromegaly Dwarfism Hyperthyroidism Graves’ Disease Hypothyroidism Cretinism Myxedema Goiter Thyroid Neoplasms Diabetes Cushing’s Syndrome Identify the cause, physiologic characteristics and manifestations, clinical significance, symptoms and possible treatment of the following 9. cardiovascular conditions when presented on a written exam: Congenital Heart Diseases Tetralogy of Fallot Septal Defects Pulmonary Stenosis Mitral Valve Prolapse Atherosclerosis Myocardial Infarction Ischemia Angina Pectoris Hypertension Cor Pulmonale Congestive Heart Failure Cyanosis Patent Ductus Arteriosis Heart Murmurs Mitral Stenosis Aortic Stenosis Hypercholesterolemia Subacute Bacterial Endocarditis Tachycardia Atherosclerosis Ventricular Fibrillation Bradycardia Rheumatic Heart Disease 10. Discuss the epidemiology and possible causes of neoplasia/cancer. Neoplastic growth Diagosis-Tumor grading/staging Squamous Cell Carcinoma Breast Cancer Prostate Cancer Lung Cancer Melanoma Benign/malignant growth Basal Cell Carcinoma Oral Metastatic Cancer Explain the etiology, clinical features and possible treatment options of the white oral lesions when presented on a written exam or projected on 11. a slide: Fordyce granules Parulis Frictional keratosis Smoker’s Melanosis Keratoacanthoma Linea alba Geographic tongue Leukoedema Leukoplakia Hyperkeratosis Hairy tongue Hairy leukoplakia Cheek chewing(morsicatio buccarum) Lichen planus Nocotine Stomatitis Proliferative Verrucous Leukoplakia White sponge nevus Oral Submucous Fibrosis Carcinoma In Situ Candidiasis Squamous Cell Carcinoma Chemical/thermal burns Acanthosis Explain the etiology, clinical features and possible treatment options of the following oral ulcers and ulcer like lesions when presented on a 12. written exam or projected on a slide: Traumatic Ulcers Necrotizing sialometaplasia Syphilis Gonorrha Actinomycosis Necrotizing Ulcerative gingivitis Deep fungal infections Aphthous ulcers Behcet syndrome Reiter syndrome Erythema multiforme Hypersensitivity reactions Lupus erythematosus Crohn disease Squamous cell carcinoma Explain the etiology, clinical features and possible treatment options of the following oral lesions that have a vesicular appearance when 13. presented on a written exam or projected on a slide: Herpes Simplex Virus infections Varicella-Zoster Virus infections Epstein-Barr Virus Cytomegalovirus Herpangina Hand, Foot, and Mouth Disease Acute Lymphonodular Pharyngitis Rubella Measles Pemphigus Vulgaris Epidermolysis bullosa Mucous membrane pemphigoid Explain the etiology, clinical features and possible treatment options of the following oral lesions in shades of red and purple when presented on 14. a written exam or projected on a slide: Pyogenic granuloma Hypersensitivity reactions Kapsosi sarcoma Peripheral giant cell