About Data Sciences International Start Studies Quickly with Help from Ponemah Analysis Modules DSI Scientific Services ™ Trusted by researchers worldwide to discover Ponemah Analysis Modules new insights into their research applications. DSI can help you streamline your studies by providing expertise you can trust. With our services, we can help Confidence you meet your software validation GLP requirements, DSI is a pioneering biomedical research company focused on preclinical Obtain accurate, consistent results via validated achieve greater implanted telemetry success and systems physiology and pharmacology. The recognized global leader in algorithms developed from scientific and peer- summarize data for confidence in your results. physiologic monitoring, DSI offers telemetry, instrumentation, software reviewed journals and services that facilitate accelerated, well-informed drug therapy and Verify analysis accuracy with real-time visual feedback Data Services development decisions. O perate with full compliance within GLP environments with the Ponemah Data Security Option (DSO) DSI will assist you with creating high quality, useable DSI serves many industries including: Pharmaceuticals, Academia, Speed reports that summarize your experimental data. The reduction in time spent on data analysis and reporting Contract Research Organizations, Biological and Chemical defense, the Efficiently refine results by re-analyzing data processes will provide you with more time to evaluate Medical Device Industry, Government and Biotechnology companies. We segments or manually editing mark placement the experimental results and plan your next logical offer solutions that are tailored specifically to meet the unique research Automatically detect noise and eliminate it from results experiment. needs of our customers. On-demand switching between time-based averages Analysis expertise include hemodynamics, seizure or beat-to-beat data, which automatically export to detection, sleep scoring and ECG evaluation Microsoft Excel® or Access® Comprehensive, useable results Customized report package Versatility Easily configure modules to analyze various signal Validation Services types from any species Instantly switch between time-based average or Our experienced team offers a customized program beat-to-beat data to help save time and reduce costs associated with Solutions for all applications, including implantable software systems validation. telemetry, jacketed telemetry and traditional hardwired solutions Customized Validation Solutions Package (VSP) with test scripts Industry experienced GLP validation specialists Contact us today for your free services consultation at Headquarters and North American Sales: European Sales: Asia Pacific Sales: [email protected] 1-800-262-9687 (U.S.) Tel: 31-13-5479356 Tel: 86-21-50793177 1-651-481-7400 (International) [email protected] [email protected] [email protected] datasci.com Better Data. Better Science. Better Data. Better Science. Copyright© 2014 Data Sciences International About Data Sciences International Start Studies Quickly with Help from Ponemah Analysis Modules DSI Scientific Services ™ Trusted by researchers worldwide to discover Ponemah Analysis Modules new insights into their research applications. DSI can help you streamline your studies by providing expertise you can trust. With our services, we can help Confidence you meet your software validation GLP requirements, DSI is a pioneering biomedical research company focused on preclinical Obtain accurate, consistent results via validated achieve greater implanted telemetry success and systems physiology and pharmacology. The recognized global leader in algorithms developed from scientific and peer- summarize data for confidence in your results. physiologic monitoring, DSI offers telemetry, instrumentation, software reviewed journals and services that facilitate accelerated, well-informed drug therapy and Verify analysis accuracy with real-time visual feedback Data Services development decisions. O perate with full compliance within GLP environments with the Ponemah Data Security Option (DSO) DSI will assist you with creating high quality, useable DSI serves many industries including: Pharmaceuticals, Academia, Speed reports that summarize your experimental data. The reduction in time spent on data analysis and reporting Contract Research Organizations, Biological and Chemical defense, the Efficiently refine results by re-analyzing data processes will provide you with more time to evaluate Medical Device Industry, Government and Biotechnology companies. We segments or manually editing mark placement the experimental results and plan your next logical offer solutions that are tailored specifically to meet the unique research Automatically detect noise and eliminate it from results experiment. needs of our customers. On-demand switching between time-based averages Analysis expertise include hemodynamics, seizure or beat-to-beat data, which automatically export to detection, sleep scoring and ECG evaluation Microsoft Excel® or Access® Comprehensive, useable results Customized report package Versatility Easily configure modules to analyze various signal Validation Services types from any species Instantly switch between time-based average or Our experienced team offers a customized program beat-to-beat data to help save time and reduce costs associated with Solutions for all applications, including implantable software systems validation. telemetry, jacketed telemetry and traditional hardwired solutions Customized Validation Solutions Package (VSP) with test scripts Industry experienced GLP validation specialists Contact us today for your free services consultation at Headquarters and North American Sales: European Sales: Asia Pacific Sales: [email protected] 1-800-262-9687 (U.S.) Tel: 31-13-5479356 Tel: 86-21-50793177 1-651-481-7400 (International) [email protected] [email protected] [email protected] datasci.com Better Data. Better Science. Better Data. Better Science. Copyright© 2014 Data Sciences International Ponemah High Performance Analysis Modules ECG Pattern Recognition Option (ECG PRO) Multi-Lead Electrocardiogram (ECG) Systemic Blood Flow (SBF) Pulmonary Compliance & Resistance (PCR/PCRP) Greatly reduce processing time using ECG PRO’s Save time by only attempting to match unmatched Multiple templates can be used in a dataset and Analyzes ECG signals to provide single and Analyzes systemic blood flow from the circulatory Analyzes pulmonary signals from either a template-based analysis as it allows the selection cycles or within specific regions templates can be added to a template library multi-lead calculations. system and eliminates drift resulting from certain types plethysmographic chamber or a pneumotachometer, of a template cardiac cycle for precise comparison Automatically adjust the ECG waveform’s cycle for use in other studies of flow meters. along with a pressure, in anesthetized or conscious • P, Q, S and T Wave Degree of Match using ECG PRO • Heart Rate to other cycles in the dataset. marks based on the template(s) Accelerates the process of locating potential • R-R Interval • QT Interval • ST Interval • P-R Interval • QR Interval • Mean • Flow Maximum • Flow Minimum • Cardiac Output animal models. arrhythmic beats • QRS Width • P Width • R, P and T Wave Heights • T Height Negative • Stroke Volume • +dQ • Iso Flow • Total Peripheral Resistance • Peak Inspiratory Flow • Peak Expiratory Flow • Tidal Volume • QR Amplitude • Variable ST Elevation • Q Alpha T Negative • Non Pulsatile Mean • Minute Volume • Respiration Rate • Inspiratory Time • Expiratory • Multiple Corrected QT Calculations • QT Dispersion • +dV/dt Max Time • Total Time • Apnea Time • Resistance • Compliance • T Area • P, T, QT and R Count • Bad, Good and Total Waves • T Peak PV Loop • Conductance • Multiple Resistances at Specified Points • Average • T Peak Interval • Noise • Timing, Channel and Dispersion Permits the display and analysis of LVP cycles Compliance • Average Resistance • Pressures at Start of Inspiration/ Information Across Multiple Leads plotted against cardiac volume cycles. Expiration • Flow and Pressure at Isovolumetric Points • Penh • Relaxation Time • Work and Power of Breathing Calculations • Tidal Blood Pressure (BP) Characterization of End Systolic Pressure Volume Relationship, Volume (Expiration) • Accumulated Volume • Inspiratory/Expiratory Analyzes arterial and venous pressures. End Diastolic Pressure Volume Relationship and Pre-Recruitable Flow 50% Stroke Work • Systolic • Diastolic • Mean • Pulse Height • Heart Rate • Time to Diaphragmatic EMG (dEMG) Peak • Ejection Time • +dP/dt •-dP/dt • %Recovery • Non Pulsatile Raw Electrical Mean Mean • Q-A Interval • Pulse Transit Time • Pulse Wave Velocity Analyzes diaphragmatic EMG signals to provide • Inter-Beat Interval • Count Analyzes any type of input signal that has no specific respiratory endpoints. analysis module. This module comes with the Ponemah Mouse over cycle match. Can get visual information for each application. • Respiration Rate • Tidal Volume* • Minute Ventilation* cycle (how well it matched and to what template) by mousing Blood Pressure Respiratory (BPR) • Inspiration Time • Expiration Time • Total Time over the complex. Derive respiration values from the cardiac cycle when • Mean • Maximum • Minimum • Period • Beats per Minute *Tidal Volume and Minute Ventilation