Efficient Professional Protein and Antibody Platforms BDH1 Antibody Basic information: Catalog No.: UMA60427 Source: Mouse Size: 50ul/100ul Clonality: Monoclonal Concentration: 1mg/ml Isotype: Mouse IgG1 Purification: Protein A affinity purified Useful Information: WB:1:500-1:1000 Applications: IHC:1:50-1:200 Reactivity: Human, Mouse Specificity: This antibody recognizes BDH1 protein. Immunogen: Recombinant protein BDH1 (3-hydroxybutyrate dehydrogenase, type 1), also known as BDH or SDR9C1, is a 343 amino acid protein that localizes to the mitochondrial ma- trix and belongs to the short-chain dehydrogenases/reductases (SDR) family. Existing as a homotetramer, BDH1 functions to catalyze the NAD+-dependent interconversion of (R)-3-hydroxybutanoate and acetoace- Description: tate, a reaction that is allosterically activated by phosphatidylcholine. As both (R)-3-hydroxybutanoate and acetoacetate are two major ketone bodies produced during fatty acid catabolism, BDH1 plays an important role in the metabolic degradation of fatty acids. The gene encoding BDH1 maps to hu- man chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Uniprot: Q02338(Human) Q80XN0(Mouse) BiowMW: 45 kDa Buffer: 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. Storage: Store at 4°C short term and -20°C long term. Avoid freeze-thaw cycles. Note: For research use only, not for use in diagnostic procedure. Data: Western blot analysis of BDH1 on HepG2 and NIH/3T3 cell lysate using anti-BDH1 antibody at 1/1,000 dilution. Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] Efficient Professional Protein and Antibody Platforms Immunohistochemical analysis of paraf- fin-embedded human prostate tissue using an- ti-BDH1 antibody. Counter stained with hematox- ylin. Immunohistochemical analysis of paraf- fin-embedded human colorectal cancer tissue using anti-BDH1 antibody. Counter stained with hematoxylin. Immunohistochemical analysis of paraf- fin-embedded human liver cancer tissue using anti-BDH1 antibody. Counter stained with hema- toxylin. Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] .