Cochrane Library Cochrane Database of Systematic Reviews Psychological therapies for the management of chronic and recurrent pain in children and adolescents (Review) Fisher E, Law E, Dudeney J, Palermo TM, Stewart G, Eccleston C Fisher E, Law E, Dudeney J, Palermo TM, Stewart G, Eccleston C. Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database of Systematic Reviews 2018, Issue 9. Art. No.: CD003968. DOI: 10.1002/14651858.CD003968.pub5. www.cochranelibrary.com Psychological therapies for the management of chronic and recurrent pain in children and adolescents (Review) Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Cochrane Trusted evidence. Informed decisions. Library Better health. Cochrane Database of Systematic Reviews T A B L E O F C O N T E N T S HEADER......................................................................................................................................................................................................... 1 ABSTRACT..................................................................................................................................................................................................... 1 PLAIN LANGUAGE SUMMARY....................................................................................................................................................................... 2 SUMMARY OF FINDINGS.............................................................................................................................................................................. 4 BACKGROUND.............................................................................................................................................................................................. 8 OBJECTIVES.................................................................................................................................................................................................. 9 METHODS..................................................................................................................................................................................................... 9 RESULTS........................................................................................................................................................................................................ 12 Figure 1.................................................................................................................................................................................................. 13 Figure 2.................................................................................................................................................................................................. 15 Figure 3.................................................................................................................................................................................................. 16 Figure 4.................................................................................................................................................................................................. 21 Figure 5.................................................................................................................................................................................................. 23 DISCUSSION.................................................................................................................................................................................................. 25 AUTHORS' CONCLUSIONS........................................................................................................................................................................... 27 ACKNOWLEDGEMENTS................................................................................................................................................................................ 28 REFERENCES................................................................................................................................................................................................ 29 CHARACTERISTICS OF STUDIES.................................................................................................................................................................. 34 DATA AND ANALYSES.................................................................................................................................................................................... 89 Analysis 1.1. Comparison 1 Treatment versus control (headache) post-treatment, Outcome 1 Pain.............................................. 90 Analysis 1.2. Comparison 1 Treatment versus control (headache) post-treatment, Outcome 2 Disability...................................... 91 Analysis 1.3. Comparison 1 Treatment versus control (headache) post-treatment, Outcome 3 Depression................................... 91 Analysis 1.4. Comparison 1 Treatment versus control (headache) post-treatment, Outcome 4 Anxiety......................................... 92 Analysis 2.1. Comparison 2 Treatment versus control (headache) follow-up, Outcome 1 Pain....................................................... 93 Analysis 2.2. Comparison 2 Treatment versus control (headache) follow-up, Outcome 2 Disability............................................... 93 Analysis 2.3. Comparison 2 Treatment versus control (headache) follow-up, Outcome 3 Depression............................................ 94 Analysis 2.4. Comparison 2 Treatment versus control (headache) follow-up, Outcome 4 Anxiety.................................................. 94 Analysis 3.1. Comparison 3 Treatment versus control (mixed pain) post-treatment, Outcome 1 Pain............................................ 95 Analysis 3.2. Comparison 3 Treatment versus control (mixed pain) post-treatment, Outcome 2 Disability.................................... 96 Analysis 3.3. Comparison 3 Treatment versus control (mixed pain) post-treatment, Outcome 3 Depression................................. 97 Analysis 3.4. Comparison 3 Treatment versus control (mixed pain) post-treatment, Outcome 4 Anxiety....................................... 97 Analysis 4.1. Comparison 4 Treatment versus control (mixed pain) follow-up, Outcome 1 Pain..................................................... 99 Analysis 4.2. Comparison 4 Treatment versus control (mixed pain) follow-up, Outcome 2 Disability............................................. 99 Analysis 4.3. Comparison 4 Treatment versus control (mixed pain) follow-up, Outcome 3 Depression.......................................... 100 Analysis 4.4. Comparison 4 Treatment versus control (mixed pain) follow-up, Outcome 4 Anxiety................................................ 100 ADDITIONAL TABLES.................................................................................................................................................................................... 101 APPENDICES................................................................................................................................................................................................. 105 WHAT'S NEW................................................................................................................................................................................................. 108 HISTORY........................................................................................................................................................................................................ 109 CONTRIBUTIONS OF AUTHORS................................................................................................................................................................... 109 DECLARATIONS OF INTEREST..................................................................................................................................................................... 110 SOURCES OF SUPPORT............................................................................................................................................................................... 110 DIFFERENCES BETWEEN PROTOCOL AND REVIEW.................................................................................................................................... 110 INDEX TERMS............................................................................................................................................................................................... 110 Psychological therapies for the management of chronic and recurrent pain in children and adolescents (Review) i Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Cochrane Trusted evidence. Informed decisions. Library Better health. Cochrane Database of Systematic Reviews [Intervention Review] Psychological therapies for the management of chronic and recurrent pain in children and adolescents Emma Fisher1, Emily Law2, Joanne Dudeney3, Tonya M Palermo2, Gavin Stewart4, Christopher Eccleston5 1Cochrane Pain, Palliative and Supportive Care Group, Pain Research Unit, Churchill Hospital, Oxford, UK. 2Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington, USA. 3Center for Child Health, Behavior, and Development, Seattle Children's