21 bus time schedule & line map 21 Newcastle upon Tyne - Chester-le-Street View In Website Mode The 21 bus line (Newcastle upon Tyne - Chester-le-Street) has 6 routes. For regular weekdays, their operation hours are: (1) Brandon: 6:10 AM - 5:42 PM (2) Chester-Le-Street: 6:25 AM - 11:46 PM (3) Chester-Le-Street: 11:27 PM (4) Durham: 5:15 AM - 11:46 PM (5) Durham: 7:05 PM (6) Newcastle upon Tyne: 4:37 AM - 11:44 PM Use the Moovit App to ƒnd the closest 21 bus station near you and ƒnd out when is the next 21 bus arriving.