Cleveland Clinic Laboratories 2013 New Molecular CPT Codes 2013 Test Name Order Code Billing Code CPT Codes 2012 CPT Codes ACADM PCR, Complete, Tier 2 ACADM 88175 81404 83891, 83894x10, 83898x10, 83904x20 ACTA2 Gene Sequencing ACTA2 88528 81403 83898x9, 83904x9, 83891 ADmark ApoE Genotype (Symptomatic) APOALZ 82397 81401 83892, 83894, 83898, 81401, 83891 ADmark PS-1 Analysis, Symptomatic PS1SY 83019 81405 83904x10, 83909x10, 83898x10, 83891 Alpha Globin (HBA1 and HBA2) Sequencing HBA12 88847 81257 New test in 2013 Alpha Thalassemia Gene Deletion ATHAL 84123 81257 83891, 83900, 83901x8, 83894 Alpha-1-Antitrypsin Quantitation and Phenotyping PHA1A 84187 81332 82103, 82104 Angelman UBE3A Sequencing UBE3A 88200 81331 83898x8, 83904x10, 83909x10 APO E Genotype APOEG 79374 81401 83891, 81401, 83898, 83896x2 ARX Sequence Analysis ARXSEQ 87860 81404 83890, 83898x5, 83894, 83904x6 Autoimmune Polyglandular Syndrome Evaluation AIRE 83293 81479 83909x14, 83891, 83898x14, 83904x14 Autosomal Dom Ataxia Evaluation AUTOAT 82179 81401, 83909x88, 83898x88, 83904x77, 81479x13 83891 Barth Syndrome, Carrier BARCAR 82536 81406 83891, 83898, 83904x2 Barth Syndrome, Initial Patient BARINI 82535 81406 83891, 83898, 83904x9 Bartonella PCR, Tissue TBART 87924 87471 83898x4, 83890, 83894 B-Cell Clonality Using BIOMED-2 PCR Primers BCBMD 87904 81261, 83891, 83900, 83909x5, 83898x3, 83901x2, 81264 83912, 81261, 81264 BCL 2 mbr (PCR) BCL2 81099 81401 81401, 83890, 83898, 83894, 83912 BCR/ABL Kinase Domain Mutation Analysis KINASE 84529 81403 83891, 83898, 83902, 83904x4, 83912, 81403, 83909x2 BCR/ABL Kinase Domain RT-PCR KDPCR 87994 81479 83891, 83902, 83898, 83912 BCR/ABL p190 RT-PCR, Qualitative 190BCR 87709 81207 83891, 83902, 83896x4, 83912, 83898x4, 81207 BCRABL p210 RTPCR Quantitative BCRPCR 82737 81206 81206, 83891, 83902, 83898x4, 83896x4, 83912 Beta Globin (HBB) Gene Sequencing BGHBB 88848 81401 New test in 2013 BRAF V600E Blood, Bone Marrow BRAFBM 88453 81210 81210, 83891, 83907, 83900, 83901, 83909 BRAF V600E Sequencing BRAF 87800 81210, 88381, 83894, 83904x2, 83912, 81210, 83891, 88381 83898, 83909x2 Cadasil Evaluation Complete CADASL 82122 81406 83891, 83898x23, 83904x23, 83909x23 Calpain 3 DNA Sequencing CALP3 83055 81406 83909x22, 83891x22, 83898x22, 83904x22 Canavan Disease Mutation, Fluid CANV2 83013 81200 83900, 83891, 83894, 83901, 83893x4, 83896x4 Canavan Disease Mutation, Whole Blood CANVAN 83014 81200 83896x4, 83893x4, 83894, 83900, 83901, 83891 Carnitine Palmitoyl Transferase II Deficiency CPT2 88144 81404 83891, 83898x5, 83904x3, 83894x3 CDKL5-Related Atypical Rett Syndrome CDKL5 87776 81406 83898x10, 83904x10, 83909x10 CEBPA Mutation Analysis CEBPA 87639 81403 83891, 83898x4, 83901, 83909x3, 83892x4, 83900, 83904x4 Chromosomal Microarray OS (oligo-based) CRMCMA 88500 81228, 83891, 88386x6, 88291 88291 1 2013 New Molecular CPT Codes (cont.) 2013 Test Name Order Code Billing Code CPT Codes 2012 CPT Codes CMT Evaluation Partial CMTEVL 82114 81325 83901x42, 83898x68, 83891, 83900, 83904x68, 83909x70, 83914x46 CMT Evaluation, Complete CMTCOM 82413 81325 83898x143, 83900, 83901x42, 83909x145, 83914x46, 83904x143, 83891 CMV Genotype CMVGEN 84053 87910 83891x15, 83890, 83909x10, 83898x5, 83904x10 COL1A1/COL1A2 DNA Sequencing COLA12 84273 81408x2 83891, 83904x62, 83898x40, 83898 COL3A1 Gene Sequencing (Blood) COL3 88543 81406 83898x25, 83904x32, 83891, 81406 Complete HNPP Evaluation HNPP 82120 81324, 83891, 83904x4, 83894x4, 83901x31, 83909x5, 81325 83914x33, 83900 Connexin 26 CON26 81933 81252 83909x3, 83891, 83904x3, 83898x3 Constitutional Whole Genome SNP Microarray WGSNP 88472 81229, 88386x4, 83891, 83892x2, 83894x3 88230 Cystic Fibrosis (ACOG) Panel CFSCRN 82502 81220 83900, 83901x30, 83912, 83914x32, 81220, 83891, 83909 Cyto P450 2C19 Genotype 2C19PL 88307 81225 83891, 83900, 83901x4, 81225, 83914x18, 83912 Cyto P450 2C19 Genotype for Clopidogrel Therapy 2C19CL 88362 81225 83891, 83900, 83901, 83914x6, 83912, 81225 Cyto P450 2D6 Genotype 2D6 87628 81226 83901x2, 83900, 81226, 83891, 83914x30, 83912 Diagnostic CF Test CFDNA 80939 81220 83891, 83901x22, 83914x97, 83900 Diagnostic CFTR Intron 8 CFTR 80937 81224 83891, 83894, 83893x3, 83898, 83896x3 DM1 DNA Test DM1DNA 82403 81401 83891, 83909, 83898 DM2 DNA Test DM2DNA 82402 81479 83891, 83909, 83898 DPD 5FU GenotypR 5FU 84203 81400 83891, 83914, 83898, 83909, 83892x3 DRPLA DNA Test DRPLA 82268 81401 83890, 83898, 83909 Duchenne/Becker Muscular Dystrophy DNA Carrier Test DBMDXS 83006 81161 83900, 83901x93, 83909x2, 83914x95, 83891 (females only) Duchenne/Becker Muscular Dystrophy DNA Del Test DBMDYS 82119 81161 83901x93, 83909x2, 83914x95, 83891, 83900 (males only) Dystonia DNA Test DYSTON 83018 81400 83909, 83891, 83898 Early Onset Obesity Evaluation OBESTY 83295 81479 83909x3, 83891, 83898x3, 83904x3 EGFR Mutation Analysis EGFR 83969 81235, 83907, 83891, 83896x29, 83898x4, 83914x29, 88381 88381, 83900, 83901x23 EGFR Mutation Analysis, Cell Pellet EGFRCP 88871 81235 New test in 2013 EGFR Mutation Analysis, Tissue EGFRTI 88877 81235, New test in 2013 88381 Endocrine Hypertension (HSD11B2) Evaluation HSD1B2 83329 81479 83909, 83891, 83898x6, 83904x6 EPM1 DNA EPMDNA 82118 81401 83891, 83892, 83894, 83896, 83897 Exercise Intolerance Mutation Profile XCISE 84411 81406, 83891, 83893x2, 83894, 83892x2, 83896x2, 81404, 83898 81479 Factor V Leiden FVLEID 79827 81241 81241, 83891, 83898, 83896x2, 83903, 83912 Factor XIII V34L DNA XIIIVL 83871 81400 83890, 83898, 83896x2 FALS Disease DNA Test FALS 82343 81403 83909x5, 83891, 83898x5, 83904x5 Familial Hypocalciuric Hypercalcemia Evaluation FHHE 83294 81479 83891, 83898x11, 83904x11 Familial Mediterranean Fever, Complete FAMMED 82936 81479 83891x7, 83898x10, 83894x7, 83904x9, 83892x4 FAP Mutation Screen FAPSCR 82499 81201, 83905x4, 83914x26, 81405, 83909x31, 81405 83906x4, 83894x8, 83898x5, 83891, 83900, 83892x4, 83901x10 2 2013 New Molecular CPT Codes (cont.) 2013 Test Name Order Code Billing Code CPT Codes 2012 CPT Codes FAP, Known Mutation FAPKNO 82498 81202 83909x2, 83891, 83894, 83898, 83892 FBN1 Gene Deletion/Duplication Analysis FBN1DD 88573 81479 83890, 83892x2, 83894, 83896x4 FBN1 Gene Sequencing Analysis FBN1 88568 81408 83890, 83898x58, 83894x58, 83904x63, 81407 Fragile X Syndrome DNA Analysis FRAGIL 82365 81243 83893, 83900, 83892x3, 83894, 83909, 83891, 83896, 83897 Friedreich’s Ataxia DNA Test FRIED 82524 81404 83891, 83894, 83898 FSHD DNA Test FSHDNA 82117 81404 83891, 83892x2, 83896, 83897, 83894, 83907 Gaucher Disease Mutation, Fluid GAUCH 83011 81251 83893x5, 83894x2, 83896x5, 83898, 83900 Gaucher Disease Mutation, Whole Blood GAUCHR 83012 81251 83893x5, 83894x2, 83896x5, 83898, 83900 GCH1 Gene Analysis GCH1 88170 81479 83891, 83898x5, 89894x2, 83904 GCK (CH) DNA Sequencing Test GCKCH 83323 81406 83891, 83904x9, 83909x9, 83898x9 GCK (NDM) DNA Sequencing Test GCKNDM 83328 81406 83909x9, 83891, 83898x9, 83904x9 Gene Analysis 21 Hydroxylase 21GENE 88173 81405 83892x2, 83894, 83900, 83901x2, 83909x16 GLA Gene Testing in Fabry Disease FABRY 82954 81405 83891, 83898x8, 83909x16 Glucose Transporter Deficiency SLC2A1 SLC2A1 88160 81479 83904x6, 83894x5, 83898x5, 83891 GLUD1 (CH) DNA Sequencing Test GLUD1 83324 81479 83898x14, 83909, 83891, 83904x14 Hemiplegic Migraine Evaluation HEMMIG 87713 81407, 83891, 83904x83, 83909x83, 83898x83 81479x2 Hereditary Pancreatitis HERPAN 82734 81401 83898x2, 83909x4, 83890, 83892x2, 83894x2 HFE (Hemochromatosis) HEMDNA 79903 81256 83891, 83896x2, 83900, 81256, 83912 HLA B5701 B5701 84337 81381 83900, 83894, 83901 HLA-A HLAA 82627 81380 83900, 83891, 83904x6 HLA-A, B & C HLABC 82817 81372 83891, 83896x90, 83900 HLA-A29 DNA Typing HLAA29 88634 81374 83891, 83896x30, 83900 HLA-B HLAB 82659 81380 83891, 83900, 83904x6 HLA-B27 PCR B27PCR 83080 81374 83891, 83898, 81374 HLA-DR HLADR 83639 81376 83898, 83891, 83896x15 Huntington Southern Blot reflex HUNTSB 84185 81479 83892, 83897, 83894, 83896, 83891 Huntington’s Disease HUNTDI 81571 81401 83891, 83909, 83898 Hypercholesterolemia (LDLR Evaluation) LDLR 83322 81401 83909, 83891, 83898x18, 83904x18 IgH and TCRB Southern Blot IMGENE 83069 81262, 83912, 83892x7, 83894x2, 83896x3, 83890 81341 IGH (SBH) IGHSB 83976 81262 83892, 83896, 81262, 83890, 83894, 83912 IgVH Mutation Analysis IGVH 88056 81263 83891, 83902, 83898x5, 83894 IgVH Mutation Analysis, Billing reflex IGVHSQ 88080 81479 83892, 83904, 83909 Immunoglobulin Heavy Chain Using Biomed-2 PCR Primers IGHPCR 87960 81261 83898x3, 83909x3, 83912, 81261, 83891 Immunoglobulin Kappa Chain using Biomed-2 PCR Primers IGKPCR 87954 81264 83891, 83900, 83909x2, 83912, 83901x4, 81264 Interleukin 28B Associated Variants, 2 SNPs IL28B 88185 81479 83891, 83900, 83896x4 IPF1 (MODY4) DNA Sequencing Test MODY4 83310 81404 83891, 83898x4, 83904x4, 83909x4 IPF1 (NDM) DNA Sequencing Test IPFNDM 83325 81404 83898x4, 83909x4, 83891, 83904x4 JAK2 Exon 12 and Non-V617F Mutation JAKNON 87775 81403 83891, 83902, 83909x2, 83898, 83904x2 JAK2 V617F Mutation Detection JAK2 83623 81270 83896x4, 81270, 83891, 83898x2, 83912 KCNJ11 (CH) DNA Sequencing Test KCNJCH 83357 81479 83898x4, 83909x4, 83891, 83904x4 KCNJ11 (NDM) DNA Sequencing Test KCNJ 83327 81479 83909x4, 83898x4, 83891, 83904x4 Kennedy’s Disease DNA Test KENEDY 82948 81401 83890, 83898, 83909 3 2013 New Molecular CPT Codes (cont.) 2013 Test Name Order Code Billing Code CPT Codes 2012 CPT Codes KIT Asp816Val Mutation Analysis KITMST 84159 81402 83909x2, 83898x2 KIT Gene Mutation AML KITAML 84158 81404 83891, 83903x5, 83898x5, 83892x5, 83904x10 KRAS Exon 1 Sequence Analysis