Kudos to NIH Technology Transfer Efforts Prepared by Office of Technology Transfer | Office of Intramural Research National Institutes of Health U.S. Department of Health & Human Services April 2016 Table of Contents 2016 Federal Laboratory Consortium | National Award | Excellence in Technology Transfer Discovery to Commercialization: New Immunotherapy for Rare Childhood Cancer, Neuroblastoma ........ 1 Development of First Immunotherapy to Treat Chordoma ......................................................................... 2 2015 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer First FDA Approval: Combination Therapy for Rare Childhood Cancer, Neuroblastoma ............................. 3 Novel Therapeutics to Treat Niemann-Pick C Disease and Other Lysosomal Disorders .............................. 4 Development of First Immunotherapy to Treat Chordoma, a Rare Bone Cancer ........................................ 6 Federal Laboratory Consortium | Mid-Atlantic Region Award | STEM Award NIH International Technology Transfer Mentoring Program........................................................................ 7 National Institutes of Health | Inventors on NIH, CDC, and FDA Patents Issued in FY 2015 Congratulations to Inventors on NIH Patents Issued in FY 2015.................................................................. 9 Congratulations to Inventors on CDC Patents Issued in FY 2015 ............................................................... 14 Congratulations to Inventors on FDA Patents Issued in FY 2015 ............................................................... 15 2014 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer The Breast Cancer Startup Challenge ........................................................................................................ 16 A Low-Cost Tissue Microarrayer Instrument to Support Improved Cancer Diagnoses .............................. 18 Interleukin-2 Receptor Gamma Deficient Mice, Widely Used Research Tools .......................................... 19 Deep Transcranial Magnetic Stimulation Coil and Therapy System ........................................................... 20 Federal Laboratory Consortium | Mid-Atlantic Region Award | Educational Institution and Federal Laboratory Partnership Discovery to Market .................................................................................................................................. 22 Licensing Executives Society | Industry-University-Government Interface Sector | ”Deals of Distinction Award™” Low-Cost Meningitis Vaccine for Sub-Saharan Africa ................................................................................ 24 National Institutes of Health | Inventors on NIH, CDC, and FDA Patents Issued in FY 2014 Congratulations to Inventors on NIH Patents Issued in FY 2014................................................................ 25 Congratulations to Inventors on CDC and FDA Patents Issued in FY 2014 ................................................. 31 2013 National Institutes of Health | Inventors on NIH Patents Issued in FY 2013 Congratulations to Inventors on NIH Patents Issued in FY 2013................................................................ 33 i Table of Contents 2013 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer Diffusion Tensor Magnetic Resonance Imaging ......................................................................................... 37 Drugs to Treat Malaria Targeting the Plasmodial Surface Anion Channel ................................................. 38 New Low-cost Meningitis Vaccine for Sub-Saharan Africa ........................................................................ 39 Federal Laboratory Consortium | National Award | Excellence in Technology Transfer Glybera®: First Gene Therapy Recommended for Approval in the West ................................................... 40 Novel Therapeutic for Tuberculosis – SQ109 ............................................................................................. 41 Sound Attenuation Canopy ........................................................................................................................ 42 2012 National Institutes of Health | Inventors on NIH Patents Issued in FY 2012 Congratulations to Inventors on NIH Patents Issued in FY 2012................................................................ 43 Licensing Executives Society | Industry-University-Government Interface Sector | ”Deals of Distinction Award™” Facilitating Access to HIV Treatment in Developing Countries .................................................................. 48 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer Sound Attenuation Canopy ........................................................................................................................ 49 Treatment of Niemann-Pick Disease Type-C with 2-hydroxypropyl-β-cyclodextrin .................................. 50 AAV Technology: Delivery Vehicle of Choice for Gene Therapy ................................................................. 52 Federal Laboratory Consortium | Mid-Atlantic Region Award | Outstanding Technology Transfer Professional Richard Rodriguez, Director, Division of Technology Development and Transfer, NIH Office of Technology Transfer ...................................................................................................................................................... 53 Federal Laboratory Consortium | Mid-Atlantic Region Award | Representative of the Year Dr. Thomas Stackhouse, Associate Director, Technology Transfer Center, National Cancer Institute ........ 54 Federal Laboratory Consortium | Mid-Atlantic Region Award | State and Local Economic Development Chief Science Officer Development Training Certificate Program (“CSO Boot Camp”) Team.................... 55 Federal Laboratory Consortium | National Award | Excellence in Technology Transfer An Interactive Software Package for the Analysis of Microarray Data ...................................................... 57 Development of Eribulin, a Potent Anti-Cancer Agent from a Marine Sponge ......................................... 59 Use of Therapeutic Antibodies as a Novel Treatment for Multiple Sclerosis ............................................. 60 Vibro-Tactile Stimulation Device and Method for Swallowing Disorders .................................................. 62 2011 National Institutes of Health | Inventors on NIH Patents Issued in FY 2011 Congratulations to Inventors on NIH Patents Issued in FY 2011................................................................ 64 ii Table of Contents 2011 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer Use of Therapeutic Antibodies as a Novel Treatment for Multiple Sclerosis ............................................. 68 Federal Laboratory Consortium | Mid-Atlantic Region Award | Outstanding Technology Transfer Professional Laurie Arrants, Director, Technology Transfer Office, National Institute of Neurological Disorders and Stroke ........................................................................................................................................................ 70 Federal Laboratory Consortium | Mid-Atlantic Region Award | State and Local Development National Cancer Institute ........................................................................................................................... 71 Federal Laboratory Consortium | Mid-Atlantic Region Award | Technology Transfer Professional Rookie of the Year Dr. Samuel Bish, Licensing and Patenting Manager, NIH Office of Technology Transfer ............................ 72 Federal Laboratory Consortium | National Award | Excellence in Technology Transfer A Lifesaving Diagnostic Test for Cancer Patients ........................................................................................ 73 Federal Laboratory Consortium | National Award | STEM Award 2010 STEM Postdoc Conference Committee ............................................................................................. 74 2010 Federal Laboratory Consortium | Mid-Atlantic Region Award | Excellence in Technology Transfer A Life-Saving Diagnostic Test for Cancer Patients ...................................................................................... 75 High-Speed Counter Current Chromatography ......................................................................................... 76 Identification and Development of Agents to Treat Glioblastoma and Other Tumors Over-expressing Nuclear Receptor CoRepressor .................................................................................................................. 77 Novel Protein-Like Therapeutics for Treatment of Cancer ........................................................................ 78 Therapeutic Antibodies for the Treatment of Cancer ................................................................................ 79 Therapeutic Immunotoxins for the Treatment of T Cell Malignancies ...................................................... 80 Federal Laboratory Consortium | National Award | Excellence in Technology Transfer Cell Line Bank for Cancer Research ........................................................................................................... 81 Innovative Techniques and Reagents for Improved