SPECIFICATION SHEET Rev 110621MAB-S0006 Mouse Anti-HFRS Virus, Hanta strain Monoclonal Antibody Mouse, Monoclonal (HFRS Virus, Hanta strain) Cat. No. DMAB3487 Lot. No. (See product label) PRODUCT INFORMATION BACKGROUND Introduction: Hantaviruses (family Bunyaviridae, genus Han- Product Overview: Monoclonal Antibody to Hemorrhagic tavirus) are rodent-borne, zoonotic (acquired from animals), fever with renal syndrome (HFRS) Virus, Hanta Strain enveloped RNA viruses, and include the causative agents of Specificity: Specific for HFRS Virus. Strain: Hanta haemorrhagic fever with renal syndrome (HFRS). The viruses Immunogen: Inactivated virus particles that cause HFRS include Hanta, Dobrava, Seoul, and Puu- Clone: C963M mala. Dobrova and Hanta viruses cause a more severe HFRS Isotype: IgG1 with fever, haemorrhage, and renal failure, and a mortality rate Host animal: Mouse. Hybridization of Sp2/0 myeloma cells of up to 15%. The mildest form of HFRS is caused by Puu- with spleen cells from BALB/c mice. mala virus. Source: Ascites Keywords: Hemorrhagic fever with renal syndrome Virus; Format: Purified, Liquid HFRS virus, Hanta strain; HFRS virus; Hemorrhagic fever with Applications: Suitable for use in ELISA. Each laboratory renal syndrome Virus, Hanta strain; Hantaviruses; Bunyaviri- should determine an optimum working titer for use in its par- dae; Hantavirus; Hemorrhagic fever with renal syndrome Vi- ticular application. Other applications have not been tested rus; HFRS Virus Dobrava, Puumala, Hanta and Seoul Strains; but use in such assays should not necessarily be excluded. HFRS; Andes virus; Amur virus; Azagny virus; Bayou virus; Purification: >95% pure (SDS-PAGE). Protein G Black Creek Canal virus; Cano Delgadito virus; Calabazo vi- chromatography rus; Catacamas virus; Choclo virus; Dobrava-Belgrade virus; Affinity Constant: Not determined El Moro Canyon virus; Hantaan virus; Imjin virus; Isla Vista virus; Khabarovsk virus; Laguna Negra virus; Limestone Can- REFERENCES yon virus; Monongahela virus; Muleshoe virus; Muju virus; New York virus; Oran virus; Playa de Oro virus; Prospect Hill 1. Sawatsky et al. (2008). "Hendra and Nipah Virus". Animal virus; Puumala virus; Rio Mamore virus; Rio Segundo virus; Viruses: Molecular Biology. Caister Academic Press. ISBN Saaremaa virus; Seoul virus; Sin Nombre virus; Soochong 978-1-904455-22-6. virus; Thailand virus; Thottapalayam virus; Topografov virus; 2. Centers for Disease Control and Prevention (CDC) (30 Tula virus April 1999). "Update: outbreak of Nipah virus—Malaysia and Singapore, 1999". MMWR Morb Mortal Wkly Rep 48 (16): 335–7. PMID 10366143. PACKAGING 3. Reynes JM, Counor D, Ong S, et al. (2005). "Nipah virus in Lyle's flying foxes, Cambodia". Emerging Infect. Dis. 11 Concentration: Lot specific (7): 1042–7. PMID 16022778. Buffer: PBS, pH 7.4 Preservative: 0.1% Sodium azide Storage: Store at 2-8°C. Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 – 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains. Creative Diagnostics. All rights reserved. 45-16 Ramsey Road Shirley, NY 11967, USA Tel: 631-624-4882 ·Fax:631-614-7828 E-mail: [email protected] www.creative-diagnostics.com .