Top 200 Pharmaceuticals by Retail Sales in 2020 M. Haziq Qureshi - The Njarðarson Group The University of Arizona 1 Humira 2 Keytruda 3 Eliquis 4 Revlimid 5 Imbruvica 6 Stelara 7 Eylea 8 Opdivo 9 Xarelto 10 Dupixent 11 Biktarvy 12 Enbrel 13 Avastin 14 Prevnar 13 15 Insulin Glargine 16 Ocrevus 17 Trulicity 18 Ibrance 19 Remicade 20 Prolia (Adalimumab) (Pembrolizumab) (Apixaban) (Lenalidomide) (Ibrutinib) (Ustekinumab) (Aflibercept) (Nivolumab) (Rivaroxaban) (Dupilumab) (Bictegravir, Emtricitabine (Etanercept) (Bevacizumab) (Pneumococcal 7-Valent (Insulin Glargine) (Ocrelizumab) (Dulaglutide) (Palbociclib) (Infliximab) (Denosumab) & Tenofovir Alafenamide) Conjugate) $20.947 Billion $14.38 Billion $14.117 Billion $12.106 Billion $9.442 Billion $7.972 Billion $7.938 Billion $7.899 Billion $7.806 Billion $7.501 Billion $7.259 Billion $6.828 Billion $6.503 Billion $5.85 Billion $5.666 Billion $5.665 Billion $5.404 Billion $5.392 Billion $5.163 Billion $5.138 Billion Immunology Oncology Cardiovascular Diseases Oncology Oncology Immunology Ophthalmology Oncology Cardiovascular Diseases Dermatology Infectious Diseases Immunology Oncology Vaccine Diabetes CNS & Anesthesia Diabetes Oncology Immunology Musculoskeletal 21 Xtandi 22 Rituxan 23 Herceptin 24 Tagrisso 25 Perjeta 26 Darzalex 27 Jardiance 28 Soliris 29mmInfluenza Vaccines 30 Cosentyx 31 Victoza 32 Gardasil 33 Trikafta 34 Tecfidera 35 Entyvio 36 Ozempic 37 Invega Sustenna 38 Lucentis 39 Simponi 40 Xolair (Enzalutamide) (Rituximab) (Trastuzumab) (Osimertinib) (Pertuzumab) (Daratumumab) (Empagliflozin) (Eculizumab) (Influenza Vaccine) (Secukinumab) (Liraglutide) (HPV Quadrivalent Vaccine) (Elexacaftor, Tezacaftor & Ivacaftor) (Dimethyl Fumarate) (Vedolizumab) (Semaglutide) (Paliperidone Palmitate) (Ranibizumab) (Golimumab) (Omalizumab) $5.1 Billion $4.987 Billion $4.725 Billion $4.328 Billion $4.326 Billion $4.19 Billion $4.108 Billion $4.064 Billion $4.006 Billion $3.995 Billion $3.961 Billion $3.939 Billion $3.864 Billion $3.841 Billion $3.823 Billion $3.755 Billion $3.653 Billion $3.542 Billion $3.467 Billion $3.372 Billion Oncology Oncology Oncology Oncology Oncology Oncology Diabetes Blood Disorders Vaccine Immunology Diabetes Vaccine Genetic Disorders CNS & Anesthesia Gastrointestinal Disorders Diabetes CNS & Anesthesia Ophthalmology Immunology Immunology 41 Orencia 42 Genvoya 43 Januvia 44 Triumeq 45 Actemra 46 Pomalyst 47 Tecentriq 48 Immunoglobulin 49 Gilenya 50 Insulin Aspart 51 Veklury 52 Symbicort 53 Advate 54 Insulin Lispro 55 Neulasta 56 Vyvanse 57 DTaP-IPV-Hib vaccine 58 Lynparza 59 Entresto 60 Aubagio (Abatacept) (Elvitegravir, Cobicistat, Emtricitabine (Sitagliptin) (Abacavir, Dolutegravir (Tocilizumab) (Pomalidomide) (Atezolizumab) (Immunoglobulin) (Fingolimod) (Insulin Aspart) (Remdesivir) (Budesonide & Formoterol) (Antihemophilic Factor (Insulin Lispro) (Pegfilgrastim) (Lisdexamfetamine) (DTaP-IPV-Hib vaccine) (Olaparib) (Sacubitril & Valsartan) (Teriflunomide) & Tenofovir Alafenamide) & Lamivudine) (Recombinant)) $3.36 Billion $3.338 Billion $3.306 Billion $3.197 Billion $3.184 Billion $3.07 Billion $3.051 Billion $3.05 Billion $3.043 Billion $2.979 Billion $2.811 Billion $2.721 Billion $2.652 Billion $2.626 Billion $2.585 Billion $2.559 Billion $2.547 Billion $2.501 Billion $2.497 Billion $2.474 Billion Immunology Infectious Diseases Diabetes Infectious Diseases Immunology Oncology Oncology Immunology CNS & Anesthesia Diabetes Infectious Diseases Respiratory Disorders Blood Disorders Diabetes Blood Disorders CNS & Anesthesia Vaccine Oncology Cardiovascular Diseases CNS & Anesthesia 61 Zytiga 62 Ofev 63 Hemlibra 64 Sprycel 65 Xeljanz 66 Spinraza 67 Alimta 68 Cimzia 69 Nexium 70 Otezla 71 Prezcobix 72 Farxiga 73 Spiriva 74 Advair 75 Tivicay 76 Imfinzi 77 Latuda 78 Janumet 79 Breo Ellipta 80 Tasigna (Abiraterone Acetate) (Nintedanib) (Emicizumab) (Dasatinib) (Tofacitinib) (Nusinersen) (Pemetrexed) (Certolizumab pegol) (Esomeprazole) (Apremilast) (Darunavir & Cobicistat) (Dapagliflozin) (Tiotropium bromide) (Salmeterol) (Dolutegravir) (Durvalumab) (Lurasidone) (Metformin & Sitagliptin) (Fluticasone Furoate & Vilanterol) (Nilotinib) $2.47 Billion $2.448 Billion $2.44 Billion $2.438 Billion $2.437 Billion $2.339 Billion $2.33 Billion $2.265 Billion $2.209 Billion $2.195 Billion $2.184 Billion $2.157 Billion $2.136 Billion $2.128 Billion $2.117 Billion $2.042 Billion $2.019 Billion $1.971 Billion $1.97 Billion $1.958 Billion Oncology Respiratory Disorders Blood Disorders Oncology Immunology Genetic Disorders Oncology Infectious Diseases Gastrointestinal Disorders Dermatology Infectious Diseases Diabetes Respiratory Disorders Respiratory Disorders Infectious Diseases Oncology CNS & Anesthesia Diabetes Respiratory Disorders Oncology 81 Tysabri 82 Kadcyla 83 Aranesp 84 Vimpat 85 Avonex 86 MMR Vaccines 87 Lenvima 88 Descovy 89 Leuprorelin 90 Mavyret 91 Jentadueto 92 Abilify Maintena 93 Taltz 94 Pradaxa 95 Xyrem 96 Promacta 97 Prograf 98 Yervoy 99 Odefsey 100 Opsumit (Natalizumab) (Trastuzumab Emtansine) (Darbepoetin Alfa) (Lacosamide) (Interferon Beta-1a) (Measles, Mumps, Rubella (Lenvatinib) (Emtricitabine & (Leuprorelin) (Glecaprevir & Pibrentasvir) (Linagliptin & Metformin) (Aripiprazole) (Ixekizumab) (Dabigatran Etexilate) (Sodium Oxybate) (Eltrombopag) (Tacrolimus) (Ipilimumab) (Emtricitabine, Rilpivirine (Macitentan) & Varicella Vaccine) Tenofovir Alafenamide) & Tenofovir Alafenamide) $1.946 Billion $1.944 Billion $1.906 Billion $1.883 Billion $1.878 Billion $1.878 Billion $1.863 Billion $1.861 Billion $1.834 Billion $1.83 Billion $1.801 Billion $1.798 Billion $1.789 Billion $1.777 Billion $1.742 Billion $1.738 Billion $1.695 Billion $1.682 Billion $1.672 Billion $1.639 Billion CNS & Anesthesia Oncology Blood Disorders CNS & Anesthesia CNS & Anesthesia Vaccine Oncology Infectious Diseases Oncology Infectious Diseases Diabetes CNS & Anesthesia Immunology Blood Disorders CNS & Anesthesia Oncology Immunology Oncology Infectious Diseases Cardiovascular Diseases 101 Lovenox 102 Epclusa 103 Samsca 104 Brilinta 105 Skyrizi 106 Rotavirus Vaccines 107 NovoMix 108 Tafinlar 109 Abraxane 110 Afinitor 111 Myrbetriq 112 Xifaxan 113mmActivase/TNKase 114mInsulin Degludec 115 Crestor 116 Truvada 117 Human Insulins 118 Sandostatin 119 DTaP Vaccines 120 Rexulti (Enoxaparin Sodium) (Sofosbuvir & Velpatasvir) (Tolvaptan) (Ticagrelor) (Risankizumab) (Rotavirus Vaccine) (Biphasic Insulin Aspart) (Dabrafenib & Trametinib) (Paclitaxel Protein Bound) (Everolimus) (Mirabegron) (Rifaximin) (Alteplase/Tenecteplase) (Insulin Degludec) (Rosuvastatin) (Emtricitabine & Tenofovir (Human Insulin) (Octreotide) (Diphtheria, Tetanus Acellular, (Brexpiprazole) Disoproxil Fumarate) and Pertussis Vaccine) $1.634 Billion $1.599 Billion $1.597 Billion $1.593 Billion $1.59 Billion $1.572 Billion $1.567 Billion $1.542 Billion $1.539 Billion $1.535 Billion $1.492 Billion $1.482 Billion $1.472 Billion $1.459 Billion $1.458 Billion $1.448 Billion $1.443 Billion $1.439 Billion $1.424 Billion $1.42 Billion Blood Disorders Infectious Diseases Cardiovascular Diseases Cardiovascular Diseases Immunology Vaccine Diabetes Oncology Oncology Oncology Nephrology Infectious Diseases Cardiovascular Diseases Diabetes Cardiovascular Diseases Infectious Diseases Diabetes Oncology Vaccine CNS & Anesthesia 121 Velcade 122 Somatuline 123 Nucala 124 Keppra 125 Tremfya 126 Jakavi 127 Copaxone 128 Venclexta 129 Lyrica 130 Mirena 131 Alecensa 132 Lipitor 133 Esbriet 134 Vyndamax 135mmMeningococcal Vaccines 136 Adempas 137mInsulin Isophane 138 Galvus Group 139 Bridion 140 Gleevec (Bortezomib) (Lanreotide) (Mepolizumab) (Levetiracetam) (Guselkumab) (Ruxolitinib) (Glatiramer acetate) (Venetoclax) (Pregabalin) (Levonorgestrel) (Alectinib) (Atorvastatin) (Pirfenidone) (Tafamidis) (Meningococcal Vaccine) (Riociguat) (Insulin Isophane) (Vildagliptin) (Sugammadex) (Imatinib) $1.389 Billion $1.386 Billion $1.378 Billion $1.359 Billion $1.347 Billion $1.339 Billion $1.337 Billion $1.337 Billion $1.313 Billion $1.308 Billion $1.292 Billion $1.291 Billion $1.29 Billion $1.288 Billion $1.269 Billion $1.261 Billion $1.26 Billion $1.199 Billion $1.198 Billion $1.188 Billion Oncology Oncology Respiratory Disorders CNS & Anesthesia Immunology Oncology CNS & Anesthesia Oncology CNS & Anesthesia Urology Oncology Cardiovascular Diseases Immunology Cardiovascular Diseases Vaccine Cardiovascular Diseases Diabetes Diabetes CNS & Anesthesia Oncology 141 NovoSeven 142 Myozyme 143 Insulin Detemir 144 Trelegy Ellipta 145 Kyprolis 146 Creon 147 Plavix 148 Uptravi 149 Ventolin 150 Pneumovax 23 151 Ultomiris 152 Forteo 153 Cyramza 154 Vectibix 155 Cymbalta 156 Pulmicort 157 Diovan Group 158 Benlysta 159 Ingrezza 160 Fabrazyme (Coagulation Factor VIIa (Alglucosidase Alfa) (Insulin Detemir) (Fluticasone Furoate, Vilanterol (Carfilzomib) (Pancrelipase) (Clopidogrel) (Selexipag) (Albuterol) (Pneumococcal Vaccine (Ravulizumab) (Teriparatide) (Ramucirumab) (Panitumumab) (Duloxetine) (Budesonide) (Hydrochlorothiazide & Valsartan) (Belimumab) (Valbenazine) (Agalsidase Beta) [Recombinant]) & Umeclidinium) Polyvalent) $1.172 Billion $1.147 Billion $1.143 Billion $1.135 Billion $1.13 Billion $1.114 Billion $1.108 Billion $1.093 Billion $1.088 Billion $1.086 Billion $1.077 Billion $1.046 Billion $1.033 Billion $1.032 Billion $1.019 Billion $1.01 Billion $1.003 Billion $997 Million $993 Million $988 Million Blood Disorders Rare Disorders Diabetes Respiratory Disorders Oncology Rare Disorders Cardiovascular Diseases Cardiovascular Diseases Respiratory Disorders Vaccine