ANNUAL REPORT 2015 Organization Index 1. DIRECTOR’S PRESENTATION .......................................................3 2. ORGANIZATION ...............................................................................5 Organisational structure . 6 Directory of groups and institutions . 8 Budget . 10 Personnel . 10 Significant activities . 11 Scientific production . 14 3. SCIENTIFIC PROGRAMMES ..................................................... 19 Bioengineering & Medical Imaging . 20 Biomaterials & Advanced Therapies . 21 Nanomedicine . 22 4. TRANSVERSAL PROGRAMMES ............................................... 23 Industrial Transfer Programme . 24 Translational Research Programme . 25 Training and Qualification Programme . 25 Dissemination Programme . 27 Internationalization Programme . 27 5. PLATFORMS ........................................ 29 Mixed platforms of the CIBER-BBN/ ICTS NANBIOSIS . 30 6. GROUPS ......................................................................................... 31 Scientific Director’s Presentation I am addressing you as the Scientific Director of the along with the Hospital Nacional de Parapléjicos CIBER-BBN for the first time to give a short review of and the start of the second edition of collaborative the work done in 2015. projects in respiratory pathologies along with the Fundación SEPAR and CIBERES. The collaborative The number of publications with CIBER- BBN affili- projects in oncology with the Fundación ECO and ation, which had been rising over the last few years, with IMIBIC went on in 2015. dropped in 2015, possibly due to the reduction in re- sources through the economic situation. We can in- Other results from last year were the coordination deed affirm nevertheless that we keep up high quali- by CIBER-BBN of one of the interCIBER excellence ty levels in our scientific production, with over 65% of projects, intended to investigate into the relationship the articles published in journals of the first quartile between diabetes and neurodegenerative disorders, and 30% in the first decile, these ratios improving in the granting of the European project DRIVE to de- respect of previous years. velop cell treatments and materials for diabetes and getting the Internationalisation Platform under way In 2015 we took the assessment given by the IS- along with CIBERES and CIBERER. CIII, through an external panel of assessors, on the work done in the four-year period from 2011-2014. The ICTS NANBIOSIS has started up, after signing This was a highly demanding test which meant ex- the agreements required by the Ministry, and has tra work and added effort for the groups. We are started to develop its strategic plan, getting under pleased with the result and take due note of the rec- way its own web page, which acts as the access ommendations suggesting the need to improve in portal for the infrastructure. Additional financing the transfer and translation indicators. from MINECO has also been obtained in the call for Excellence Networks. The most noteworthy cooperation work in our field continues to be our intramural projects. The 49 pro- No group has had to leave CIBER-BBN as a result jects from the 2014-2015 period went on through- of the previous year’s assessment, and furthermore, out 2015, all focussing on some specific pathology. a new group joined in 2015, after the selection pro- cess in a competitive call launched by the ISCIII. Four new projects have been got under way in coop- eration with companies, in which these defray 50% I would lastly like to thank all those of you who form of the cost of the project. This initiative represents a part of the CIBER-BBN for your ongoing daily efforts, major thrust forward to take the results of research making such a decisive contribution to the consoli- into the industrial setting. These transfer initiatives dation of our centre’s scientific excellence. have been complemented with the onset of an ac- With best regards, tion implying cooperation with consultancy compa- nies to promote the search for outside investments. Ramón Martínez Máñez In the field of cooperation with the clinic, I would like Scientific Director to stress the thematic forum arranged in May 2015 CIBER-BBN I Annual report 2015 I 3 2 Organization 2 Organization Organization Organisational structure The CIBER-BBN is one of the eight thematic areas The External Scientific Committee is a body for forming the Centro de Investigación Biomédica scientific support and advice, made up of relevant en Red (CIBER), a Spanish research consortium personalities in the field of health sciences in the field of biomedical research with great standing out for their professional or scientific scientific potential, under the Instituto de Salud careers in line with the objectives of the of the Carlos III (ISCIII) – Ministry of the Economy and thematic area. Competitiveness. The senior administrative bodies of the CIBER-BBN The bioengineering, biomaterials and nanomedi- are the Governing Body and the Permanent Com- cine area is made up of 44 research groups, keep- mission, common for all the CIBER research areas. ing its independence as regards scientific man- The Governing Body is made up of three agement. Its organisational structure is based on representatives of the ISCIII and by an institutional the research groups belonging to this and its ac- representative of each of the centres in the tivity revolves around the Research Programmes consortium. It is presided over by the Director of and Transversal Programmes, with a coordinator the ISCIII and meets every six months. for each Programme belonging to the Steering The Permanent Commission is an executive Committee. Scientific decisions are made by the committee made up by the ISCIII and 8 members Scientific Director, advised by said Steering Com- of the Governing Body, who can be renewed on an mittee and the External Scientific Committee. annual basis. The Steering Committee is presided over by the Both the operation and the purposes of the Scientific Director and made up of the coordinators governing, support and advisory bodies are of the programmes and Managing Director of the established in the statutes of the CIBER. CIBER. Members of the Steering Advisory Comittee of CIBER-BBN NAME POST HELD Ramón Martínez-Máñez Scientific Director José Becerra Deputy Scientific Director Jordi Aguiló Bioengineering and Medical Imaging Coordinator Julio San Román Biomaterials and Advanced Therapies Coordinator M. Pilar Marco Nanomedicine Coordinator Jaume Veciana ICTS / Platforms Coordinator Simó Schwartz Industrial Transfer Coordinator Ramon Mangues Translating Clinical Coordinator Raimon Jané Training Coordinator Jesús Santamaría Strategic Plan Coordinator Manuel Sánchez Managing Director Scientific Director Assistant: Begoña Pérez 6 I Annual report 2015 I CIBER-BBN Organization External Scientific Advisory Committee of CIBER-BBN NAME INSTITUTION Niilo Saranummi VTT Technical Research Centre, Finlandia Leif Sörnmo Biomedical Engineering Department, University of Lund, Suecia Begoña Castro Scientific Director Histocell, Spain Matthias Epple Centre for Medical Biotechnology, Universität Duisburg-Essen, Alemania Centre for Research in Medical Devices (CÚRAM) National University of Ireland - Galway, Abhay Pandit Irlanda Business development in NanoMedicine at CEA-Leti, Chair of the Executive Board of Patrick Boisseau European Technology Platform on Nanomedicine, Francia Wofgang Parak Philipps Universität Marburg, Alemania Shaare Zedek Medical Center, Oncology Institute The Hebrew University of Jerusalem, Alberto A. Gabizon Israel Joan Bigorra Director of Innovation, Hospital Clinic de Barcelona, Spain Pilar Calvo Chief of Pharmaceutical Development in PHARMAMAR, Spain Medical Advisory Board NAME POST HELD Joan Bigorra Llosas Director of Innovation at Hospital Clínic, Barcelona. Arrhythmia Division Manager of the Cardiology Department at Hospital Universitario Arcadi García Alberola Virgen de la Arrixaca, Murcia. Enrique Gómez Barrena Specialist in the area of Traumatology and Orthopaedics at Hospital Universitario La Paz. Mª José Martí Doménech Neurology Department at Hospital Clínic, Barcelona. Specialist in the Area of Ophthalmology of the Complejo Universitario Hospitalario, José M. Ruíz Moreno Albacete. Josep Tabernero Caturla Onco-haematology Coordinator at Hospital Vall d´Hebrón. Scientific Management NAME PROGRAMME Theodora Tsapikouni Bioengineering and Medical Imaging Aída Castellanos Páez Biomaterials and Advanced Therapies Johanna Katharina Scheper Nanomedicine Fernando Santos Benito Industrial Transfer Jesús M. Izco Zaratiegui Platforms (ICTS NANBIOSIS) Technical Unit See list of personnel: http://www.ciber-bbn.es/en/about-us/structure/head-office CIBER-BBN I Annual report 2015 I 7 Organization Directory of groups and institutions Group leader Institution Centre Centre Prov Universitat Autònoma de Aguiló Llobet, Jordi Centro Nacional de Microelectrónica Barcelona Barcelona Albericio Palomera, Institut de Recerca Biomedica Institut de Recerca Biomedica Barcelona Fernando (IRB Barcelona) (IRB Barcelona) Universitat Autònoma de Arús Caralto, Carles Facultad de Biociencias Barcelona Barcelona Becerra Ratia, José Universidad de Málaga Facultad de Ciencias Málaga Bellón Caneiro, Juan Universidad de Alcalá Facultad de Medicina Madrid Manuel Blanco Fernández, Agencia Estatal Consejo Superior Instituto de Química Avanzada Barcelona Jerónimo de Investigaciones Científicas de Cataluña Calonge Cano, Universidad de Valladolid Instituto de Oftalmobiología