Product datasheet [email protected] ARG58448 Package: 50 μl anti-Sp7 / Osterix antibody Store at: -20°C Summary Product Description Rabbit Polyclonal antibody recognizes Sp7 / Osterix Tested Reactivity Hu Predict Reactivity Ms, Rat, Cow, Gpig, Hrs, Rb Tested Application IHC-P Host Rabbit Clonality Polyclonal Isotype IgG Target Name Sp7 / Osterix Antigen Species Human Immunogen Synthetic peptide around the C-terminal region of Human Sp7 / Osterix. (within the following sequence: RTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSP) Conjugation Un-conjugated Alternate Names Transcription factor Sp7; OI11; osterix; OSX; OI12; Zinc finger protein osterix Application Instructions Predict Reactivity Note Predicted homology based on immunogen sequence: Cow: 100%; Guinea Pig: 93%; Horse: 93%; Mouse: 92%; Rabbit: 86%; Rat: 93% Application table Application Dilution IHC-P Assay-dependent Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Positive Control Jurkat Calculated Mw 45 kDa Properties Form Liquid Purification Affinity purified. Buffer PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. Preservative 0.09% (w/v) Sodium azide Stabilizer 2% Sucrose Concentration Batch dependent: 0.5 - 1 mg/ml www.arigobio.com 1/2 Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. Note For laboratory research only, not for drug, diagnostic or other use. Bioinformation Gene Symbol SP7 Gene Full Name Sp7 transcription factor Background This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] Function Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity). [UniProt] Images ARG58448 anti-Sp7 / Osterix antibody IHC-P image Immunohistochemistry: Paraffin-embedded Human intestine stained with ARG58448 anti-Sp7 / Osterix antibody. www.arigobio.com 2/2 Powered by TCPDF (www.tcpdf.org).