Supplemental Table 2 Genes down-regulated (<0.5) in Stat3∆/∆ compared with Stat3flox/flox Probe ID Gene Symbol Gene Description Entrez gene ID 1460599_at Ermp1 endoplasmic reticulum metallopeptidase 1 226090 1460463_at H60c histocompatibility 60c 670558 1460431_at Gcnt1 glucosaminyl (N-acetyl) transferase 1, core 2 14537 1459979_x_at Zfp68 zinc finger protein 68 24135 1459747_at --- --- --- 1459608_at --- --- --- 1459168_at --- --- --- 1458718_at --- --- --- 1458618_at --- --- --- 1458466_at Ctsa cathepsin A 19025 1458345_s_at Colec11 collectin sub-family member 11 71693 1458046_at --- --- --- 1457769_at H60a histocompatibility 60a 15101 1457680_a_at Tmem69 transmembrane protein 69 230657 1457644_s_at Cxcl1 chemokine (C-X-C motif) ligand 1 14825 1457639_at Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H 108664 1457260_at 5730409E04Rik RIKEN cDNA 5730409E04Rik gene 230757 1457070_at --- --- --- 1456893_at --- --- --- 1456823_at Gm70 predicted gene 70 210762 1456671_at Tbrg3 transforming growth factor beta regulated gene 3 21378 1456211_at Nlrp10 NLR family, pyrin domain containing 10 244202 1455881_at Ier5l immediate early response 5-like 72500 1455576_at Rinl Ras and Rab interactor-like 320435 1455304_at Unc13c unc-13 homolog C (C. elegans) 208898 1455241_at BC037703 cDNA sequence BC037703 242125 1454866_s_at Clic6 chloride intracellular channel 6 209195 1453906_at Med13l mediator complex subunit 13-like 76199 1453522_at 6530401N04Rik RIKEN cDNA 6530401N04 gene 328092 1453354_at Gm11602 predicted gene 11602 100380944 1453234_at 1300002K09Rik RIKEN cDNA 1300002K09 gene 74152 1453144_at Pisd-ps3 phosphatidylserine decarboxylase, pseudogene 3 66776 1447831_s_at Mtmr7 myotubularin related protein 7 54384 1447655_x_at Sox6 SRY-box containing gene 6 20679 1447584_s_at Myct1 myc target 1 68632 1447343_at Nrp2 neuropilin 2 18187 1447299_at --- --- --- 1447284_at Trem1 triggering receptor expressed on myeloid cells 1 58217 1447260_at Gm10499 /// Gm8909 predicted gene 10499 /// predicted gene 8909 667977 /// 69717 1447223_at --- --- --- 1447116_at --- --- --- 1447075_at LOC100503847 hypothetical LOC100503847 100503847 1446337_at Htt huntingtin 15194 1446323_at Atf7ip activating transcription factor 7 interacting protein 54343 1445824_at Zfp458 zinc finger protein 458 238690 1445605_s_at Fam135a family with sequence similarity 135, member A 68187 1445188_at --- --- --- 1445101_at --- --- --- 1444900_at D18Ertd289e DNA segment, Chr 18, ERATO Doi 289, expressed 52490 1444790_at Hsbp1l1 heat shock factor binding protein 1-like 1 66255 1444740_at Lass3 LAG1 homolog, ceramide synthase 3 545975 1444620_at --- --- --- 1444619_x_at Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional 16913 peptidase 7) 1444487_at Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) 79235 1443913_at --- --- --- 1443584_at 1110028C15Rik RIKEN cDNA 1110028C15 gene 68691 1443480_at --- --- --- 1443430_at --- --- --- 1442979_at --- --- --- 1442273_at Ccdc158 coiled-coil domain containing 158 320696 1441975_at Acpp acid phosphatase, prostate 56318 1441971_at --- --- --- 1441941_x_at Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 20724 1441876_x_at Zfp93 zinc finger protein 93 22755 1441855_x_at Cxcl1 chemokine (C-X-C motif) ligand 1 14825 1441438_at Gpc6 glypican 6 23888 1441417_at Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 16430 1441202_at --- --- --- 1440589_at --- --- --- 1440440_at --- --- --- 1440339_at Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 18605 1440336_at C130013H08Rik RIKEN cDNA C130013H08 gene 100327264 1440307_at Gtf3c2 general transcription factor IIIC, polypeptide 2, beta 71752 1440264_at --- --- --- 1440228_at Ranbp6 RAN binding protein 6 240614 1440052_at --- --- --- 1439878_at Ivl involucrin 16447 1439703_at Cd200r1 CD200 receptor 1 57781 1439695_a_at Kif20b kinesin family member 20B 240641 1439620_at Car13 carbonic anhydrase 13 71934 1439562_at F730047E07Rik RIKEN cDNA F730047E07 gene 212377 1439019_at Fras1 Fraser syndrome 1 homolog (human) 231470 1438987_at Fam71d family with sequence similarity 71, member D 70897 1438701_at Bicd1 bicaudal D homolog 1 (Drosophila) 12121 1438515_at Zfp207 zinc finger protein 207 22680 1438426_at Shisa4 shisa homolog 4 (Xenopus laevis) 77552 1437989_at Pde8b phosphodiesterase 8B 218461 1437842_at Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 403178 1437789_at Birc6 baculoviral IAP repeat-containing 6 12211 1437673_at Wnt5a wingless-related MMTV integration site 5A 22418 1437580_s_at Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 18005 1437264_at BC051142 cDNA sequence BC051142 407788 1436852_at E130308A19Rik RIKEN cDNA E130308A19 gene 230259 1436706_at Mmgt1 membrane magnesium transporter 1 236792 1436590_at Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B 244416 1436538_at Ankrd37 ankyrin repeat domain 37 654824 1436251_at Pde1c phosphodiesterase 1C 18575 1436118_at Vangl2 vang-like 2 (van gogh, Drosophila) 93840 1435836_at Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 228026 1435752_s_at Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 20928 1435472_at Kremen1 kringle containing transmembrane protein 1 84035 1435307_at Ankrd34b ankyrin repeat domain 34B 218440 1435264_at Emilin2 elastin microfibril interfacer 2 246707 1435236_at Tceanc transcription elongation factor A (SII) N-terminal and central domain containing 245695 1435190_at Chl1 cell adhesion molecule with homology to L1CAM 12661 1435075_at Tmem106b transmembrane protein 106B 71900 1435069_at BC064078 cDNA sequence BC064078 408064 1435065_x_at Vav2 vav 2 oncogene 22325 1434855_at Amdhd2 amidohydrolase domain containing 2 245847 1434749_at BC067068 cDNA sequence BC067068 216292 1434725_at Gramd1c GRAM domain containing 1C 207798 1434711_at BC030867 cDNA sequence BC030867 217216 1434539_at Lrrn3 leucine rich repeat protein 3, neuronal 16981 1433615_at Tmem117 transmembrane protein 117 320709 1432906_at --- --- --- 1432391_at Ccdc21 coiled-coil domain containing 21 70012 1432088_at Veph1 ventricular zone expressed PH domain homolog 1 (zebrafish) 72789 1431754_at 4930578N16Rik RIKEN cDNA 4930578N16 gene 75051 1431269_at Prdx4 peroxiredoxin 4 53381 1431220_at 2810416G20Rik RIKEN cDNA 2810416G20 gene 100040353 1431131_s_at A630007B06Rik RIKEN cDNA A630007B06 gene 213993 1430995_at Tmx3 thioredoxin-related transmembrane protein 3 67988 1430257_at Card11 caspase recruitment domain family, member 11 108723 1429277_at --- --- --- 1429197_s_at Rabgap1l RAB GTPase activating protein 1-like 29809 1429123_at Rab27a RAB27A, member RAS oncogene family 11891 1429098_s_at Nhej1 nonhomologous end-joining factor 1 75570 1429021_at Epha4 Eph receptor A4 13838 1428692_at Hddc3 HD domain containing 3 68695 1428304_at Esco2 establishment of cohesion 1 homolog 2 (S. cerevisiae) 71988 1460521_a_at Obfc2a oligonucleotide/oligosaccharide-binding fold containing 2A 109019 1460438_at Lysmd1 LysM, putative peptidoglycan-binding, domain containing 1 217779 1460427_a_at Adam28 a disintegrin and metallopeptidase domain 28 13522 1460423_x_at Gm5571 /// Igk-V1 predicted gene 5571 /// immunoglobulin kappa chain variable 1 (V1) 16081 /// 434025 1460364_at Gtf2ird1 general transcription factor II I repeat domain-containing 1 57080 1460329_at B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 56386 1460247_a_at Skp2 S-phase kinase-associated protein 2 (p45) 27401 1460197_a_at Steap4 STEAP family member 4 117167 1459902_at 2700007P21Rik RIKEN cDNA 2700007P21 gene 212772 1456174_x_at Ndrg1 N-myc downstream regulated gene 1 17988 1456169_at Tstd1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 226654 1455898_x_at Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 20527 1455892_x_at --- --- --- 1455475_at 3110057O12Rik RIKEN cDNA 3110057O12 gene 269423 1455466_at Gpr133 G protein-coupled receptor 133 243277 1455435_s_at Chdh choline dehydrogenase 218865 1455053_a_at Dcun1d1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 114893 1454849_x_at Clu clusterin 12759 1453748_a_at Kif23 kinesin family member 23 71819 1453596_at Id2 inhibitor of DNA binding 2 15902 1453427_at Csnk2a1 casein kinase 2, alpha 1 polypeptide 12995 1453360_a_at Tex9 testis expressed gene 9 21778 1453278_a_at Clip4 CAP-GLY domain containing linker protein family, member 4 78785 1452801_at Pigk phosphatidylinositol glycan anchor biosynthesis, class K 329777 1452614_at Bcl2l15 BCLl2-like 15 229672 1452593_a_at Tceb1 transcription elongation factor B (SIII), polypeptide 1 67923 1452557_a_at --- --- --- 1452463_x_at Gm10883 predicted gene 10883 384419 1452426_x_at --- --- --- 1452417_x_at Gm10883 /// Gm1420 /// predicted gene 10883 /// predicted gene 1420 /// predicted gene 7202 /// 110759 /// 16071 /// 16114 /// 384419 /// Gm7202 /// Igk-C /// Igk-J1 immunoglobulin kappa chain, constant region /// immunoglobulin kappa chain, 546213 /// 637227 /// Igk-V28 joining region, 1 /// immunoglobulin kappa chain variable 28 (V28) 1452415_at Actn1 actinin, alpha 1 109711 1452391_at Cxadr coxsackie virus and adenovirus receptor 13052 1452314_at Kif11 kinesin family member 11 16551 1452297_at Ccnt2 cyclin T2 72949 1452277_at Arsg arylsulfatase G 74008 1452114_s_at Igfbp5 insulin-like growth factor binding protein 5 16011 1452072_at Myct1 myc target 1 68632 1451671_at Gorasp1 golgi reassembly stacking protein 1 74498 1451538_at