2008 EUR O TRANSPLANT INTER N A TIO N AL FOUN D A TION A n n u a l R e p o r t 2 0 0 8 63082 om 2005 29-06-2006 13:40 Pagina 1 2008 Edited by Arie Oosterlee and Axel Rahmel Eurotransplant Aims Eurotransplant mission statement Mission Service organization for transplant candidates through the collaborating transplant programs within the organization. Goals • To achieve an optimal use of available donor organs and tissues • To secure a transparent and objective selection system, based upon medical and ethical criteria • To assess the importance of factors which have the greatest influence on waiting list mortality and transplant results • To support donor procurement to increase the supply of donor organs and tissues • To further improve the results of transplantation through scientific research and to publish and present these results • Promotion, support and coordination of organ donation and transplantation in the broadest sense of terms CIP-GEGEVENS KONINKLIJKE BIBLIOTHEEK, DEN HAAG Annual Report/Eurotransplant International Foundation.–Leiden: Eurotransplant Foundation. -III., graf., tab. Published annually Annual report 2008 / ed. by Arie Oosterlee and Axel Rahmel ISBN-13: 978-90-71658-28-0 Keyword: Eurotransplant Foundation; annual reports. 2 Table of contents - Board of Eurotransplant International Foundation 5 - TRANSPLANT PROGRAMS AND THEIR DELEGATES IN 2008 6 - Renal programs 6 - Heart programs 7 - Lung programs 8 - Liver programs 9 - Pancreas (islet) programs 10 - Tissue typing laboratories 11 - Foreword 13 1. Report of the Board and the central office of 14 Stichting Eurotransplant International Foundation 1.1 General 14 1.2 Policy 17 1.3 Quality Assurance & Safety 19 1.4 Advisory Committees 20 1.5 Recommendations approved 23 2. Eurotransplant: donation, waiting lists and transplants 26 - Introduction 26 Table 2.1 Number of deceased organ donors used for a transplant, by country of origin, from 2004 to 2008 26 Table 2.2(i) Number of deceased organ donors used for a transplant, by organ, from 2004 to 2008 27 Table 2.2(ii) Number of deceased organ donors used for a transplant, by organ and donor country, in 2008 27 Table 2.3(i) Demographic data on deceased organ donors, used for a transplant, from 2004 to 2008 27 Table 2.3(ii) Demographic data on deceased organ donors, used for a transplant, in 2008 28 Table 2.4a(i) Number of donors, used in a transplant, by type of donor, from 2004 to 2008 28 Table 2.4a(ii) Number of donors, used in a transplant, by type and country of origin of donor, in 2008 28 Table 2.4b(i) Number of deceased donors, used in a transplant, by type of donor, from 2004 to 2008 28 Table 2.4b(ii) Number of deceased donors, used in a transplant, by type and country of origin of donor, in 2008 29 Table 2.4c(i) Non-heart beating donors from 2004 to 2008 29 Table 2.4c(ii) Non-heart beating donors in 2008 29 Table 2.4d(i) Transplants from NHB donors from 2004 to 2008 29 Table 2.4d(ii) Transplants from NHB donors in 2008 30 Table 2.5(i) Active Eurotransplant waiting list, by organ, as per December 31, from 2004 to 2008 30 Table 2.5(ii) Active Eurotransplant waiting list, by organ, as per December 31, 2008 31 Table 2.6(i) Registration events on the Eurotransplant waiting list, by organ from 2004 to 2008 31 Table 2.6(ii) Registration events on the Eurotransplant waiting list, by organ and country, in 2008 32 Table 2.7(i) Number of transplanted organs, by organ, by donor type, from 2004 to 2008 32 Table 2.7(ii) Number of transplanted organs, by organ, by donor type, by country of transplant, in 2008 32 Table 2.8(i) Transplants from 2004 to 2008 33 Table 2.8(ii) Transplants in 2008, by transplant country 34 Table 2.9(i) Mortality on the Eurotransplant waiting list, by date of death, from 2004 to 2008 34 Table 2.9(ii) Mortality on the Eurotransplant waiting list in 2008 34 3. Kidney: donation, waiting lists and transplants 35 Table 3.1(i) Deceased donors / kidneys in Eurotransplant, from 2004 to 2008 35 Table 3.1(ii) Deceased donors / kidneys in Eurotransplant in 2008 35 Table 3.2(i) Active kidney transplant waiting list, as per December 31, from 2004 to 2008 - characteristics 35 Table 3.2(ii) Active kidney transplant waiting list, as per December 31 , 2008 - characteristics 36 Table 3.3(i) Active kidney only transplant waiting list, as per December 31, from 2004 to 2008 - characteristics 36 Table 3.3(ii) Active kidney only transplant waiting list, as per December 31, 2008 - characteristics 36 Table 3.4(i) Kidney transplants - characteristics from 2004 to 2008 37 Table 3.4(ii) Kidney transplants - characteristics - 2008 38 Table 3.5(i) Living donor kidney transplants - kidney only - 2004 to 2008 39 Table 3.5(ii) Living donor kidney transplants - kidney only - 2008 40 Figure 3.1 Dynamics of the Eurotransplant kidney transplant waiting list and transplants between 1969 and 2008 40 4. Thoracic organs: donation, waiting lists and transplants 41 Table 4.1(i) Deceased donors / hearts in Eurotransplant from 2004 to 2008 41 Table 4.1(ii) Deceased donors / hearts in Eurotransplant in 2008 41 Table 4.2(i) Deceased donors / lungs in Eurotransplant from 2004 to 2008 41 Table 4.2(ii) Deceased donors / lungs in Eurotransplant in 2008 42 Table 4.3(i) Active heart transplant waiting list, as per December 31, from 2004 to 2008 - characteristics 42 3 Table 4.3(ii) Active heart transplant waiting list as per December 31, 2008 - characteristics 42 Table 4.4(i) Active heart only transplant waiting list as per December 31, from 2004 to 2008 - characteristics 42 Table 4.4(ii) Active heart only transplant waiting list as per December 31, 2008 - characteristics 43 Table 4.5(i) Active heart + lung transplant waiting list as per December 31, from 2004 to 2008 - characteristics 44 Table 4.5(ii) Active heart + lung transplant waiting list, as per December 31, 2008 - characteristics 44 Table 4.6(i) Active heart + lung transplant waiting list as per December 31, from 2004 to 2008 - characteristics 44 Table 4.6(ii) Active heart + lung transplant waiting list as per December 31, 2008 - characteristics 44 Table 4.7(i) Active lung transplant waiting list as per December 31, from 2004 to 2008 - characteristics 45 Table 4.7(ii) Active lung transplant waiting list as per December 31, 2008 - characteristics 45 Table 4.8(i) Active lung only transplant waiting list, as per December 31, from 2004 to 2008 - characteristics 45 Table 4.8(ii) Active lung only transplant waiting list, as per December 31, 2008 - characteristics 46 Table 4.9(i) Heart transplants from 2004 to 2008 - characteristics 46 Table 4.9(ii) Heart transplants 2008 - characteristics 47 Table 4.10(i) Heart + lung transplants from 2004 to 2008 - characteristics 48 Table 4.10(ii) Heart + lung transplants 2008 - characteristics 48 Table 4.11(i) Lung transplants from 2004 to 2008 - characteristics 49 Table 4.11(ii) Lung transplants 2008 - characteristics 50 Figure 4.1 Dynamics of the Eurotransplant heart waiting list and transplants between 1991 and 2008 50 Figure 4.2 Dynamics of the Eurotransplant heart + lung waiting list and heart + lung transplants and 50 Eurotransplant lung waiting list and lung transplants between 1991 and 2008 5. Liver and intestine: donation, waiting lists and tranplants 51 Table 5.1(i) Deceased donor livers in Eurotransplant from 2004 to 2008 51 Table 5.1(ii) Deceased donor livers in Eurotransplant in 2008 51 Table 5.2(i) Active liver transplant waiting list, as per December 31, from 2004 to 2008 - characteristics 52 Table 5.2(ii) Active liver transplant waiting list, as per December 31, 2008 - characteristics 52 Table 5.3(i) Active liver only transplant waiting list as per December 31, from 2004 to 2008 - characteristics 52 Table 5.3(ii) Active liver only transplant waiting list as per December 31, 2008 - characteristics 53 Table 5.4(i) Liver transplants from 2004 to 2008 - characteristics 54 Table 5.4(ii) Liver transplants 2008 - characteristics 54 Table 5.5(i) Living donor liver transplants - liver only - from 2004 to 2008 55 Table 5.5(ii) Living donor liver transplants - liver only - 2008 56 Figure 5.1 Dynamics of the Eurotransplant liver waiting list and liver transplants between 1991 and 2008 56 - Intestine transplants 2008 57 Table 5.6 Number of intestinal transplants performed in 2008 57 6. Pancreas and islets: donation, waiting lists and transplants 58 Table 6.1(i) Deceased donors / pancreas in Eurotransplant from 2004 to 2008 58 Table 6.1(ii) Deceased donors / pancreas in Eurotransplant in 2008 58 Table 6.2(i) Active pancreas transplant waiting list as per December 31, from 2004 to 2008 - characteristics 58 Table 6.2(ii) Active pancreas transplant waiting list as per December 31 , 2008 - characteristics 59 Table 6.3a(i) Active pancreas only transplant waiting list as per December 31, from 2004 to 2008 - characteristics 59 Table 6.3a(ii) Active pancreas only transplant waiting list as per December 31, 2008 - characteristics 59 Table 6.3b(i) Active kidney + pancreas transplant waiting list as per December 31, from 2004 to 2008 - characteristics 60 Table 6.3b(ii) Active kidney + pancreas transplant waiting list as per December 31, 2008 - characteristics 60 Table 6.4a(i) Pancreas transplants from 2004 to 2008 - characteristics 61 Table 6.4a(ii) Pancreas transplants 2008 - characteristics 62 Table 6.4b(i) Number of pancreas islet transplants from 2004 to 2008 62 Table 6.4b(ii) Number of pancreas islet transplants in 2008 62 Table 6.4c(i) Pancreas transplants from 2004 to 2008 - characteristics 62 Table 6.4c(ii) Pancreas transplants 2008 - characteristics 63 Figure 6.1 Dynamics of the Eurotransplant pancreas+kidney and islet+kidney waiting list, pancreas+kidney, islet+kidney, 63 pancreas and islet-only transplants between 1991 and 2008 7.