11TH ANNUAL BEHAVIOR, BIOLOGY, and CHEMISTRY: Translational Research in Addiction San Antonio, Texas | Omni Colonnade | 2-3 March 2019 BBC Publications BBC 2011 Stockton Jr SD and Devi LA (2012) Functional relevance of μ–δ opioid receptor heteromerization: A Role in novel signaling and implications for the treatment of addiction disorders: From a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence 121, 167-72. PMC3288266 Traynor J (2012) μ-Opioid receptors and regulators of G protein signaling (RGS) proteins: From a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence 121, 173-80. PMC3288798 Lamb K, Tidgewell K, Simpson DS, Bohn LM and Prisinzano TE (2012) Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: New concepts in mu opioid receptor pharmacology: From a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence 121, 181-88. PMC3288203 Whistler JL (2012) Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: From a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence 121, 189-204. PMC4224378 BBC 2012 Zorrilla EP, Heilig M, de Wit H and Shaham Y (2013) Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism. Drug and Alcohol Dependence 128, 175-86. PMC3596012 BBC 2013 De Biasi M, McLaughlin I, Perez EE, Crooks PA, Dwoskin LP, Bardo MT, Pentel PR and Hatsukami D (2014) Scientific overview: 2013 BBC plenary symposium on tobacco addiction. Drug and Alcohol Dependence 141, 107-17. PMC4227301 BBC 2014 Reith ME, Blough BE, Hong WC, Jones KT, Schmitt KC, Baumann MH, Partilla JS, Rothman RB and Katz JL (2015) Behavioral, biological and chemical perspectives on atypical agents targeting the dopamine transporter. Drug and Alcohol Dependence 147, 1-19. PMC4297708 BBC 2015 Grandy DK, Miller GM and Li JX (2016) “TAARgeting addiction”– The Alamo bears witness to another revolution. Drug and Alcohol Dependence. 159, 9-16. PMC4724540 BBC 2016 Bachtell RK, Jones JD, Heinzerling KG, Beardsley PM, Comer SD (2017) Glial and neuroinflammatory targets for treating substance use disorders. Drug and Alcohol Dependence 180, 156-70. PMC5790191 2019 Behavior, Biology, and Chemistry: Translational Research in Addiction Oral Communications Acknowledgements Sponsors National Institute on Drug Abuse University of Texas at El Paso University of Texas Health Science Center at San Antonio Office of the President Department of Pharmacology Office of the Vice President for Research Department of Physiology Office of the Dean, Graduate School of Biomedical Sciences Department of Psychiatry Office of the Dean, School of Nursing Center for Biomedical Neuroscience San Antonio Life Sciences Institute Robert A Welch Distinguished University Chair Endowment Addiction Research, Treatment & Training (ARTT) Center of Excellence FUNDING FOR THIS CONFERENCE WAS MADE POSSIBLE (IN PART) BY R13DA029347 FROM THE NATIONAL INSTITUTE ON DRUG ABUSE. THE VIEWS EXPRESSED IN WRITTEN CONFERENCE MATERIALS OR PUBLICATIONS AND BY SPEAKERS AND MODERATORS DO NOT NECESSARILY REFLECT THE OFFICIAL POLICIES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES; NOR DOES MENTION BY TRADE NAMES, COMMERCIAL PRACTICES, OR ORGANIZATIONS IMPLY ENDORSEMENT BY THE U.S. GOVERNMENT. Additional Donations From: Mohammad Ansari Laura Erwin Ashleigh Matthews James Cook Bill Fantegrossi Katharine Nelson Andrew Coop Kevin Freeman Savanah Saldana Christopher Cunningham Brenda Gannon Bryan Sears Martin Leigh 1 2019 Behavior, Biology, and Chemistry: Translational Research in Addiction Local Organizing Oral CommunicationsProgram Travel Awards Committee Committee Committee Charles P France (Chair) Gregory T Collins (Chair) Brett C Ginsburg (Chair) William P Clarke Wouter Koek Eddie Castaneda Gregory T Collins T Celeste Napier Christopher W Cunningham Rheaclare Fraser-Spears Janet L Neisewander David N Kearns Brett C Ginsburg Katherine M Serafine Thomas M Keck Wouter Koek Thomas E Prisinzano Therese A Kosten Richard J Lamb David R Maguire Katherine M Serafine Cindal C Dominguez Session Chairs Alessandro Bonifazi Richard J Lamb E Andrew Townsend William P Clarke David Matuskey Katherine M Serafine Gregory T Collins Samantha J McClenahan James H Woods Stephen J Kohut T Celeste Napier Poster Judges Caroline Bass Michael Gatch T Celeste Napier Kelly Berg Emily Jutkiewicz Katherine Serafine Carlos Bolanos-Guzman Brian Kangas Ellen Walker Andrew Coop Stephen Kohut Victoria Taylor Christopher Cunningham Therese Kosten Jenny Wilkerson Bill Fantegrossi Lance McMahon Kevin Freeman Ian Mendez Oral Presentation Judges Lisa Baker Comfort Boateng Marisa Lopez-Cruzan Linda Perrotti Thomas Keck David Maguire Administrative and Technical Support Fermin C Barrera Christopher Cruz Cindal C Dominguez Melanie L Herrera 2 2019 Behavior, Biology, and Chemistry: Translational Research in Addiction Maharaj Ticku MemorialOral Communications Travel Fellowship for New Investigators Jun-Xu Li (2012) Kevin B Freeman (2013) Christopher W Cunningham (2014) Brian D Kangas (2015) Clinton E Canal (2016) Thomas M Keck (2017) Comfort A Boateng (2018) Stephen J Kohut (2019) Travel Awardees Mohammad Ansari Francisco Flores Ramirez Sasin Payakachat Lauren Armbruster Hunter Franks Lauren Russell Francisco Battiti Daniel Gabriel Savanah Saldaña Nina Beltran Kayla Galindo Francisco Sarabia Michael Berquist Israel Garcia Samantha Scott Jennifer Betts Priscilla Giner Bryan Sears Alessandro Bonifazi Nzia Hall Paloma Serna Eric Bow Ramsey Hanna Omar Sial Michael Bremmer Ethan Hardin Justin Strickland Megan Brenner William Hyatt Andrew Townsend Sonvia Brown Chad Johnson Christopher Tschumi Trent Bullock Saurabh Kokane Kyle Urquhart Gwendolyn Burgess Martin Leigh Annika Vannan Veronica Campbell Michael Leonard Anna Vongphrachanh Andrea Casiraghi Jianfeng Liu Catheryn Wilson Samuel Castillo Arantxa Martinez Lisa Wooldridge Pierpaolo Cordone Ashleigh Matthews Ruyan Wu Andrea Dimet Samantha McClenahan Austin Zamarripa Madeline Elsey Justin McGraw Julio Zuarth Gonzalez Laura Erwin Katharine Nelson Janelle Fetko Samuel Obeng 3 2019 Behavior, Biology, and Chemistry: Translational Research in Addiction Oral Communications OralProgram Communications Overview FRIDAY 1 MARCH 2019 1:45 PM – 3:45 PM Pathways to Careers in Science Workshop – UT Health Campus 4:00 PM – 5:00 PM San Antonio Substance Use Symposium Panel Discussion – UT Health Campus 2:00 PM – 6:00 PM Registration – Omni Colonnade 5:15 PM Bus departs from UT Health to the Omni Colonnade 6:00 PM Busses depart from Omni Colonnade to Opening Reception at La Vista Terrace on the Riverwalk 6:00 PM – 9:00 PM BBC Opening Reception, La Vista Terrace on the Riverwalk SATURDAY 2 MARCH 2019 7:00 AM – 5:00 PM Registration 8:00 AM – 9:05 AM Poster Session I 9:05 AM – 9:10 AM Welcome and Opening Remarks 9:10 AM – 11:30 AM Plenary Symposium: Imaging Addiction Deborah C Mash; Mapping cocaine addiction circuitry in postmortem human brain Congwu Du; Advanced optical imaging of the neurotoxic and functional consequences of cocaine self- administration in rats David Matuskey; Utilizing PET to image neurotransmitter systems in substance abuse Nelly Alia-Klein; Imaging disease and recovery in addicted individuals (Chairs: David Matuskey and Gregory T Collins) 11:30 AM – 1:15 PM Lunch 11:50 AM – 1:05 PM Panel Discussion: How scientists can be more visible and impactful in their communities T Celeste Napier Wendy Rigby David Martin Davies Will C Sansom 1:15 PM – 3:05 PM Open Oral Communications I (Chairs: T Celeste Napier and Alessandro Bonifazi ) 3:05 PM – 3:20 PM Coffee Break 3:20 PM – 5:20 PM Open Oral Communications II (Chairs: Katherine M Serafine and Samantha J McClenahan ) 5:20 PM – 5:35 PM Coffee Break 5:35 PM – 6:35 PM Special Lecture: Stephen M Husbands; The orvinols and close analogs: from opioid maintenance to relapse prevention (Chair: James H Woods) 6:35 PM – 7:35 PM Poster Session and Cocktail Hour 7:35 PM – 9:25 PM Dinner After Dinner Speaker: Alan Frazer; Making it in modern science (Chair: William P Clarke) Hospitality and entertainment SUNDAY 3 MARCH 2019 7:45 AM Travel Awardee Group Photo 8:00 AM – 9:05 AM Poster Session II 9:10 AM – 11:10 AM Open Oral Communications III (Chairs: Stephen J Kohut and E Andrew Townsend ) 11:10 AM – 11:25 AM Coffee Break 11:25 AM – 12:25 PM Special Lecture: Sharon L Walsh; The opioid crisis: leveraging science to change hearts and minds (Chair: Richard J Lamb) 12:25 PM Presentation of travel awards and awards for oral and poster presentations 12:30 PM – 1:30 PM Adjournment and Lunch Maharaj Ticku Memorial Travel Fellowship for New Investigators Travel Awardee 4 2019 Behavior, Biology, and Chemistry: Translational Research in Addiction Oral Communications Oral CommunicationsProgram Details Friday 1 March 2019 1:45 PM – 3:45 PM Pathways to Careers in Science Workshop – UT Health Campus 4:00 PM – 5:00 PM San Antonio Substance Use Symposium Panel Discussion – UT Health Campus Harm reduction strategies and other cutting-edge approaches for substance use disorders Opening Reception La Vista Terrace on the Riverwalk 6:00 PM Busses depart from Omni Colonnade 6:30 PM - 9:00 PM Welcome Reception – La Vista Terrace on the Riverwalk 8:30 PM – 9:00 PM Buses depart for Omni Colonnade Enjoy the Alamo and beautiful San Antonio Riverwalk. Buses will depart from Omni Colonnade at 6:00 PM to La Vista Terrace for dinner and drinks. Buses will return to Omni Colonnade 8:30 PM - 9:00 PM. A badge is required to board the bus and for dinner. Additional tickets can be purchased in advance or at the registration desk for $50.00. Saturday 2 March 2019 Poster Session I 8:00 AM - 9:05 AM La Joya Welcome and Opening Remarks 9:05 AM - 9:10 AM Ballroom Plenary Symposium 9:10 AM – 11:30 AM Imaging Addiction (Chairs: David Matuskey, and Gregory T Collins) Drug addiction is a chronic disorder characterized by compulsive drug use that is thought to arise from, and induce, dysregulation in brain circuits important for reward, motivation, and memory.