IAEA HUMAN HEALTH SERIES No. 26 SERIES No. IAEA HUMAN HEALTH Proper cancer management requires highly accurate imaging for characterizing, staging, restaging, assessing response to therapy, prognosticating and detecting recurrence of disease. The ability to provide, in a single imaging session, detailed anatomical and metabolic/functional information has established positron emission tomography/computed tomography (PET/CT) as an indispensable imaging procedure in the management of many types of cancer. The reliability of the images acquired on a PET/CT scanner depends on the quality of the imaging technique. This publication addresses this important aspect of PET/CT imaging, namely, how to perform an 18F-fl uorodeoxyglucose (FDG) PET/CT scan in an adult patient with cancer. It provides a comprehensive overview that can be used both by new PET/CT centres in the process of starting up and by established imaging centres for updating older protocols. IAEA HUMAN HEALTH SERIES IAEA HUMAN HEALTH SERIES Standard Operating Procedures for PET/CT: A Practical Approach for Use in Adult Oncology A Practical Approach for PET/CT: Operating Procedures Standard No. 26 Standard Operating Procedures for PET/CT: A Practical Approach for Use in Adult Oncology INTERNATIONAL ATOMIC ENERGY AGENCY VIENNA ISBN 978–92–0–143710–5 ISSN 2075–3772 RELATED PUBLICATIONS IAEA HUMAN HEALTH SERIES PUBLICATIONS APPROPRIATE USE OF FDG-PET FOR THE MANAGEMENT OF CANCER PATIENTS The mandate of the IAEA human health programme originates from Article II of IAEA Human Health Series No. 9 its Statute, which states that the “Agency shall seek to accelerate and enlarge the STI/PUB/1438 (85 pp.; 2010) contribution of atomic energy to peace, health and prosperity throughout the world”. ISBN 978–92–0–101610–2 Price: €39.00 The main objective of the human health programme is to enhance the capabilities of IAEA Member States in addressing issues related to the prevention, diagnosis and PLANNING A CLINICAL PET CENTRE treatment of health problems through the development and application of nuclear IAEA Human Health Series No. 11 techniques, within a framework of quality assurance. STI/PUB/1457 (146 pp.; 2010) Publications in the IAEA Human Health Series provide information in the areas ISBN 978-92-0-104610-9 Price: €42.00 of: radiation medicine, including diagnostic radiology, diagnostic and therapeutic nuclear medicine, and radiation therapy; dosimetry and medical radiation physics; and stable QUALITY ASSURANCE FOR PET AND PET/CT SYSTEMS isotope techniques and other nuclear applications in nutrition. The publications have a IAEA Human Health Series No. 1 broad readership and are aimed at medical practitioners, researchers and other STI/PUB/1393 (145 pp; 2009) professionals. International experts assist the IAEA Secretariat in drafting and reviewing ISBN 978-92-0-103609-4 Price: €32.00 these publications. Some of the publications in this series may also be endorsed or co- sponsored by international organizations and professional societies active in the relevant STRATEGIES FOR CLINICAL IMPLEMENTATION AND QUALITY fields. MANAGEMENT OF PET TRACERS There are two categories of publications in this series: STI/PUB/1344 (197 pp.; 2009) ISBN 978-92-0-107008-1 Price: €44.00 IAEA HUMAN HEALTH SERIES Publications in this category present analyses or provide information of an A GUIDE TO CLINICAL PET IN ONCOLOGY: IMPROVING CLINICAL advisory nature, for example guidelines, codes and standards of practice, and quality MANAGEMENT OF CANCER PATIENTS assurance manuals. Monographs and high level educational material, such as graduate IAEA TECDOC Series No. 1605 texts, are also published in this series. IAEA-TECDOC-1605 (61 pp; 2008) ISBN 978-92-0-110608-7 Price: €15.00 IAEA HUMAN HEALTH REPORTS Human Health Reports complement information published in the IAEA Human THE ROLE OF PET/CT IN RADIATION TREATMENT PLANNING FOR Health Series in areas of radiation medicine, dosimetry and medical radiation physics, CANCER PATIENT TREATMENT and nutrition. These publications include reports of technical meetings, the results of IAEA TECDOC Series No. 1603 IAEA coordinated research projects, interim reports on IAEA projects, and educational IAEA TECDOC-1603 (43 pp; 2008) material compiled for IAEA training courses dealing with human health related subjects. ISBN 978-92-0-110408-3 Price: €15.00 In some cases, these reports may provide supporting material relating to publications issued in the IAEA Human Health Series. CYCLOTRON PRODUCED RADIONUCLIDES: GUIDANCE ON FACILITY DESIGN AND PRODUCTION OF [18F]FLUORODEOXYGLUCOSE (FDG) All of these publications can be downloaded cost free from the IAEA web site: IAEA Radioisotopes and Radiopharmaceuticals Series No. 3 http://www.iaea.org/Publications/index.html STI/PUB/1515 (153 pp; 2012) Further information is available from: ISBN 978-92-0-117310-2 Price: €55.00 Marketing and Sales Unit International Atomic Energy Agency RADIATION PROTECTION IN NEWER MEDICAL IMAGING TECHNIQUES: Vienna International Centre PET/CT PO Box 100 Safety Reports Series No. 58 1400 Vienna, Austria STI/PUB/1343 (41 pp; 2008) ISBN 978-92-0-106808-8 Price: €28.00 Readers are invited to provide their impressions on these publications. Information may be provided via the IAEA web site, by mail at the address given above, or by email to: [email protected]. www.iaea.org/books STANDARD OPERATING PROCEDURES FOR PET/CT: A PRACTICAL APPROACH FOR USE IN ADULT ONCOLOGY The following States are Members of the International Atomic Energy Agency: AFGHANISTAN GUATEMALA PANAMA ALBANIA HAITI PAPUA NEW GUINEA ALGERIA HOLY SEE PARAGUAY ANGOLA HONDURAS PERU ARGENTINA HUNGARY PHILIPPINES ARMENIA ICELAND POLAND AUSTRALIA INDIA PORTUGAL AUSTRIA INDONESIA AZERBAIJAN IRAN, ISLAMIC REPUBLIC OF QATAR BAHRAIN IRAQ REPUBLIC OF MOLDOVA BANGLADESH IRELAND ROMANIA BELARUS ISRAEL RUSSIAN FEDERATION BELGIUM ITALY RWANDA BELIZE JAMAICA SAUDI ARABIA BENIN JAPAN SENEGAL BOLIVIA JORDAN SERBIA BOSNIA AND HERZEGOVINA KAZAKHSTAN SEYCHELLES BOTSWANA KENYA SIERRA LEONE BRAZIL KOREA, REPUBLIC OF BULGARIA KUWAIT SINGAPORE BURKINA FASO KYRGYZSTAN SLOVAKIA BURUNDI LAO PEOPLE’S DEmOCRATIC SLOVENIA CAMBODIA REPUBLIC SOUTH AFRICA CAMEROON LATVIA SPAIN CANADA LEBANON SRI LANKA CENTRAL AFRICAN LESOTHO SUDAN REPUBLIC LIBERIA SWAZILAND CHAD LIBYA SWEDEN CHILE LIECHTENSTEIN SWITZERLAND CHINA LITHUANIA COLOMBIA LUXEMBOURG SYRIAN ARAB REPUBLIC CONGO MADAGASCAR TAJIKISTAN COSTA RICA MALAWI THAILAND CÔTE D’IVOIRE MALAYSIA THE FORMER YUGOSLAV CROATIA MALI REPUBLIC OF MACEDONIA CUBA MALTA TOGO CYPRUS MARSHALL ISLANDS TRINIDAD AND TOBAGO CZECH REPUBLIC MAURITANIA TUNISIA MAURITIUS DEMOCRATIC REPUBLIC TURKEY OF THE CONGO MEXICO UGANDA DENMARK MONACO DOMINICA MONGOLIA UKRAINE DOMINICAN REPUBLIC MONTENEGRO UNITED ARAB EMIRATES ECUADOR MOROCCO UNITED KINGDOM OF EGYPT MOZAMBIQUE GREAT BRITAIN AND EL SALVADOR MYANMAR NORTHERN IRELAND ERITREA NAMIBIA UNITED REPUBLIC ESTONIA NEPAL OF TANZANIA ETHIOPIA NETHERLANDS UNITED STATES OF AMERICA FIJI NEW ZEALAND URUGUAY FINLAND NICARAGUA UZBEKISTAN FRANCE NIGER GABON NIGERIA VENEZUELA GEORGIA NORWAY VIETNAM GERMANY OMAN YEMEN GHANA PAKISTAN ZAMBIA GREECE PALAU ZIMBABWE The Agency’s Statute was approved on 23 October 1956 by the Conference on the Statute of the IAEA held at United Nations Headquarters, New York; it entered into force on 29 July 1957. The Headquarters of the Agency are situated in Vienna. Its principal objective is “to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world’’. The following States are Members of the International Atomic Energy Agency: IAEA HUMAN Health SERIES No. 26 AFGHANISTAN GUATEMALA PANAMA ALBANIA HAITI PAPUA NEW GUINEA ALGERIA HOLY SEE PARAGUAY ANGOLA HONDURAS PERU ARGENTINA HUNGARY PHILIPPINES ARMENIA ICELAND POLAND AUSTRALIA INDIA PORTUGAL AUSTRIA INDONESIA AZERBAIJAN IRAN, ISLAMIC REPUBLIC OF QATAR BAHRAIN IRAQ REPUBLIC OF MOLDOVA BANGLADESH IRELAND ROMANIA BELARUS ISRAEL RUSSIAN FEDERATION BELGIUM ITALY RWANDA BELIZE JAMAICA SAUDI ARABIA BENIN JAPAN SENEGAL STANDARD OPERATING BOLIVIA JORDAN SERBIA BOSNIA AND HERZEGOVINA KAZAKHSTAN SEYCHELLES BOTSWANA KENYA SIERRA LEONE BRAZIL KOREA, REPUBLIC OF PROCEDURES FOR PET/CT: BULGARIA KUWAIT SINGAPORE BURKINA FASO KYRGYZSTAN SLOVAKIA BURUNDI LAO PEOPLE’S DEmOCRATIC SLOVENIA A PRACTICAL APPROACH FOR CAMBODIA REPUBLIC SOUTH AFRICA CAMEROON LATVIA SPAIN USE IN ADULT ONCOLOGY CANADA LEBANON SRI LANKA CENTRAL AFRICAN LESOTHO SUDAN REPUBLIC LIBERIA SWAZILAND CHAD LIBYA SWEDEN CHILE LIECHTENSTEIN SWITZERLAND CHINA LITHUANIA COLOMBIA LUXEMBOURG SYRIAN ARAB REPUBLIC CONGO MADAGASCAR TAJIKISTAN COSTA RICA MALAWI THAILAND CÔTE D’IVOIRE MALAYSIA THE FORMER YUGOSLAV CROATIA MALI REPUBLIC OF MACEDONIA CUBA MALTA TOGO CYPRUS MARSHALL ISLANDS TRINIDAD AND TOBAGO CZECH REPUBLIC MAURITANIA TUNISIA MAURITIUS DEMOCRATIC REPUBLIC TURKEY OF THE CONGO MEXICO UGANDA DENMARK MONACO DOMINICA MONGOLIA UKRAINE DOMINICAN REPUBLIC MONTENEGRO UNITED ARAB EMIRATES ECUADOR MOROCCO UNITED KINGDOM OF EGYPT MOZAMBIQUE GREAT BRITAIN AND EL SALVADOR MYANMAR NORTHERN IRELAND ERITREA NAMIBIA UNITED REPUBLIC ESTONIA NEPAL OF TANZANIA ETHIOPIA NETHERLANDS UNITED STATES OF AMERICA FIJI NEW ZEALAND URUGUAY FINLAND NICARAGUA UZBEKISTAN FRANCE NIGER GABON NIGERIA VENEZUELA GEORGIA NORWAY VIETNAM GERMANY OMAN YEMEN GHANA PAKISTAN ZAMBIA GREECE PALAU ZIMBABWE The Agency’s Statute was approved on 23 October 1956 by the Conference on the Statute of the IAEA held at United Nations Headquarters, New York; it entered into force on