WO 2010/048705 Al

WO 2010/048705 Al

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date 6 May 2010 (06.05.2010) WO 2010/048705 Al (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 36/54 (2006.01) A23L 1/30 (2006.01) kind of national protection available): AE, AG, AL, AM, A23C 9/152 (2006.01) A61K 36/258 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, A23G 1/48 (2006.01) A61P 3/10 (2006.01) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, A23L 1/236 (2006.01) A23L 1/221 (2006.01) DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, Number (21) International Application p KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, PCT/CA2009/001528 M E M ( M K M N M Z N A N ( (22) International Filing Date: NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, 23 October 2009 (23 10 2009) SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (25) Filing Language: English (84) Designated States (unless otherwise indicated, for every (26) Publication Language: English kind of regional protection available): ARlPO (BW, GH, (30) Priority Data: G M ' K E ' L S ' ' M Z ' N A ' S D ' S L ' S Z ' T Z ' U G ' Z M ' 2,642,1 84 28 October 2008 (28.10.2008) CA ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, TJ, 2 667 831 29 May 2009 (29 05 2009) CA ™)> European (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (71) Applicant (for all designated States except US): ALLE- MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, GIANCE EQUITY CORPORATION [CA/CA]; 79 Old TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Forest Hill Road, Toronto, Ontario M5P 2R6 (CA). ML, MR, NE, SN, TD, TG). (72) Inventors; and Declarations under Rule 4.17: (75) Inventors/Applicants (for US only): SOLOMON, David ,. , . , , , , , [CA/CA]; 299 Rimrock Road, Toronto, Ontario M3J 3J9 a S t0 ant s entitlement to apply for and be granted (CA). GOMEZ, Hector, J . [US/US]; 5105 Rue Ven- a patent (Rule 4.1 7(H)) dome, Lutz, Florida 33535 (US). — ofinventorship (Rule 4.1 7(iv)) (74) Agent: HUGHES, Ivor, M.; Heenan Blaikie LLP, Bay Published: Adelaide Centre, Suite 2900, P.O. Box 2900, 333 Bay _ h international search report (Art 21(3)) Street, Toronto, Ontario M5H 2T4 (CA). (54) Title: COMPOSITION FOR THE MAINTENANCE OF BLOOD SUGAR LEVELS COMPRISING CINNAMON AND GINSENG (57) Abstract: A composition is disclosed which comprises cinnamon or cinnamon extract such as cinnamon aqueous extract TC 112 and panax ginseng or extract from panax ginseng standardized to 1.5 to 7% ginsenosides and may comprise an artificial sweetener. The composition is embodied in the form of a pill or food product with 120 mg of cinnamon aqueous extract and 120 mg of ginseng standardized to 1 5 to 7% ginsenosides. The composition is used as a daily dosage for improvement of cognitive function, prevention or treatment of Alzheimer's disease, maintenance or lowering of blood-sugar levels, prevention of arterial dis ease or the improvement of cognitive function in diabetics. TITLE OF INVENTION Composition foi the maintenance of blood sugai le\els compiising cinnamon and ginseng FIELD OF INVENTION The present application relates generally to nutritional and medicinal supplements. More particularly, the present invention relates to a composition containing effective amounts of cinnamon for example ginseng extract and cinnamon for example cinnamon extract or their equivalents of polyphenols found in cinnamon and ginosenosides found in ginseng BACKGROUND OF INVENTION Those who have diabetes generally have difficulty in maintaining proper blood sugar levels. Many foods and products are made available to the general public and provide general nutritional health but often are not directed to persons afflicted with diabetes and other glucose/sugar intolerances Diabetics may also be prone to other conditions such as coronary artery diseases, dementia, and Alzheimer's disease which may affect memory, cognitive function, and mental health. The use of ginseng or ginseng extract has been documented as a supplement for use with diabetic patents. However, the use of ginseng in such applications generally requires a relatively large dosage, for example at least 200 mg of standardized ginseng extract. It would be advantageous to provide a composition which address at least some of the above-noted difficulties. SUMMARY OF INVENTION The present application generally provides a composition comprising ginseng having polyphenols in an effective amount preferably a cinnamon extract and ginseng having an effective amount of genosides preferably a ginseng extract. Thus, the composition may comprise a mixture of polyphenols found in cinnamon and ginsenosides found in ginseng, each in effective amounts. In another aspect, the present application provides for a use of such a composition to improve cognitive function in diabetics. In another aspect, the present application provides for a food product containing the composition In another aspect of the invention, the composition may be combined with various ingredients such as coca, chocolate, dairy food products, artificial sweeteners (good for diabetics), vitamins and supplements, for example composing thiamine of Bl, Riboflavin, calcium and Niacin. For example, according to other aspects of the invention, a package of ingredients is provided each package containing an artificial sweetener and at least one ingestible ingredient in an effective non-toxic amount which reduces the impact of blood sugar levels in the body, on the body when the contents of the package are ingested. According to another aspect of the invention, bulk mix is provided containing an artificial sweetener and at least one ingestible ingredient in an effective non-toxic amount which reduces the impact of blood sugar levels in the body, on the body when ingested. According to another aspect of the invention, a package (packet or sachet) is provided containing an artificial sweetener and at least one ingestible beneficial ingredient for reducing the impact of blood sugar levels in the body, on the human body. According to another aspect of the invention, a bulk mix is provided containing an artificial sweetener and at least one ingestible beneficial ingredient in an effective non- toxic amount for reducing the impact of the undesired effect of the ingestion of the table sugar on the human body According to another aspect of the invention, the package may be such wherein the at least one beneficial ingredient is selected from an effective amount of cinnamon (or polyphenols found therein), an effective amount of ginseng (or ginsenosides found therein) or combinations thereof. According to another aspect of the invention, the mix may be such wherein the at least one beneficial ingredient is selected from an effective amount of cinnamon (or polyphenols found therein), an effective amount of ginseng (or ginsenosides found therein) or combinations thereof. According to another aspect of the invention, a packet is provided containing an artificial sweetener and at least one ingestible ingredient in an effective non-toxic amount which reduces the impact of the blood sugar levels in the body on the body when the contents of the package are ingested wherein the at least one ingestible ingredient comprises at least two ingestible ingredients (in effective non-toxic amounts) which reduce the impact of the blood sugar levels in the body on the body when the contents of the package are ingested. According to another aspect of the invention, a mix is provided containing a first ingestible ingredient having an artificial sweetener and at least one ingestible ingredient in an effective non-toxic amount which reduces the impact of blood sugar levels in the body, on the body wherein the at least one ingestible ingredient comprises at least two ingestible ingredients (in effective non-toxic amounts) which reduce the impact of the blood sugar levels in the body, on the body when ingested. According to another aspect of the invention, a paper package is provided containing an artificial sweetener and at least one ingestible ingredient selected from an effective amount of cinnamon (or polyphenols found in cinnamon), ginseng (or gmsenosides found in ginseng, and combinations thereof, for reducing the impact of blood sugar levels in the body on the human body when all are ingested. According to another aspect of the invention, a bulk mix is provided containing an artificial sweetener and at least one ingesuble ingredient selected from an effective amount of cinnamon (or polyphenols found in cinnamon), ginseng (or gmsenosides found in ginseng, and combinations thereof, for reducing the impact of blood sugar levels in the body on the human body when all are ingested According to another aspect of the invention, a comestible product suitable for ingestion by a human is provided comprising a combination of Products A and B packaged together, Product A being an ingesuble product (other than table sugar) by the human and Product B reduces the impact of blood sugar levels in the body on the human body. According to another aspect of the invention, the product may be such wherein Product A is an artificial sweetener and Product B comprises cinnamon or ginseng or combinations thereof, each in effective non-toxic amounts. According to another aspect of the invention, the product may be such wherein when Product B is cinnamon, the amount of cinnamon present comprises an effective non-toxic amount to maintain or reduce blood sugar levels in the body.

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