The Journal of PHARMACOLOGY And Experimental Therapeutics A Publication of the American Society for Pharmacology and Experimental Therapeutics September 2018 Vol. 366, No. 3 Contents MINIREVIEWS Neuroprotective Effects of Nicotine on Hippocampal Long-Term Potentiation in Brain Disorders 498 Karim A. Alkadhi Downloaded from Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders 519 Richard M. Kostrzewa, Karolina Wydra, Malgorzata Filip, Cynthia A. Crawford, Sanders A. McDougall, Russell W. Brown, Dasiel O. Borroto-Escuela, Kjell Fuxe, and Raul R. Gainetdinov CARDIOVASCULAR S Calcitriol Accelerates Vascular Calcification Irrespective of Vitamin K Status in a Rat Model of Chronic Kidney Disease 433 jpet.aspetjournals.org with Hyperphosphatemia and Secondary Hyperparathyroidism Kristin M. McCabe, Jason G. Zelt, Martin Kaufmann, Kimberly Laverty, Emilie Ward, Henry Barron, Glenville Jones, Michael A. Adams, and Rachel M. Holden S Contributions of Nrf2 to Puerarin Prevention of Cardiac Hypertrophy and its Metabolic Enzymes Expression in Rats 458 Gan-Jian Zhao, Ning Hou, Shao-Ai Cai, Xia-Wen Liu, Ai-Qun Li, Chuan-Fang Cheng, Yin Huang, Li-Rong Li, Yun-Pei Mai, Shi-Ming Liu, Cai-Wen Ou, Zhen-Yu Xiong, Xiao-Hui Chen, Min-Sheng Chen, and Cheng-Feng Luo at ASPET Journals on September 25, 2021 CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY S Antagonizing SET Augments the Effects of Radiation Therapy in Hepatocellular Carcinoma through Reactivation of 410 PP2A-Mediated Akt Downregulation Chao-Yuan Huang, Man-Hsin Hung, Chi-Ting Shih, Feng-Shu Hsieh, Chiung-Wen Kuo, Ming-Hsien Tsai, Shih-Shin Chang, Yung-Jen Hsiao, Li-Ju Chen, Tzu-I. Chao, and Kuen-Feng Chen Efavirenz and Lopinavir Levels in HIV-Infected Women and Their Nursing Infants, in Mali 479 Aboubacar Alassane Oumar, Kadiatou Bagayoko-Maiga, Aliou Bahachimi, Mamoudou Maiga, Marie-Christine Cere, Zoumana Diarra, Etienne Chatelut, Mariam Sylla, Robert Leo Murphy, Sounkalo Dao, and Peggy Gandia DRUG DISCOVERY AND TRANSLATIONAL MEDICINE In Vitro and In Vivo Characterization of Novel Stable Peptidic Ghrelin Analogs: Beneficial Effects in the Settings of 422 Lipopolysaccharide-Induced Anorexia in Mice Martina Holubová, Miroslava Blechová, Anna Kákonová, Jaroslav Kunes, Blanka Zelezná, and Lenka Maletínská METABOLISM, TRANSPORT, AND PHARMACOGENOMICS S A Specific Probe Substrate for Evaluation of CYP4A11 Activity in Human Tissue Microsomes and a Highly Selective 446 CYP4A11 Inhibitor: Luciferin-4A and Epalrestat Satoshi Yamaori, Noriyuki Araki, Mio Shionoiri, Kurumi Ikehata, Shinobu Kamijo, Shigeru Ohmori, and Kazuhito Watanabe NEUROPHARMACOLOGY Honokiol Ameliorates Amyloidosis and Neuroinflammation and Improves Cognitive Impairment in Alzheimer’s Disease 470 Transgenic Mice Dongmei Wang, Xiaohui Dong, and Chenying Wang NYX-2925 Is a Novel N-Methyl-D-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat 485 Models of Neuropathic Pain Nayereh Ghoreishi-Haack, Jessica M. Priebe, Jacqueline D. Aguado, Elizabeth M. Colechio, Jeffrey S. Burgdorf, M. Scott Bowers, Cassia N. Cearley, M. Amin Khan, and Joseph R. Moskal S Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role 509 of Sphingosine-1-Phosphate Receptor Adaptation Laura J. Sim-Selley, Jenny L. Wilkerson, James J. Burston, Kurt F. Hauser, Virginia McLane, Sandra P. Welch, Aron H. Lichtman, and Dana E. Selley S Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects 527 Weimin C. Hong, Michael J. Wasko, Derek S. Wilkinson, Takato Hiranita, Libin Li, Shuichiro Hayashi, David B. Snell, Jeffry D. Madura, Christopher K. Surratt, and Jonathan L. Katz Downloaded from jpet.aspetjournals.org at ASPET Journals on September 25, 2021 S Supplemental material is available at jpet.aspetjournals.org. About the cover: Molecular dynamics (MD) of inhibitor-DAT complexes. See the article by Hong et al. (dx.doi.org/10.1124/jpet.118.250498)..