Patentamt Europaisches ||| || 1 1| || || || ||| || || ||| || ||| || (19) J European Patent Office Office europeen des brevets (11) EP 0 702 548 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publicationation and mention (51) |nt. CI.6: A61 K 7/48 of the grant of the patent: 14.10.1998 Bulletin 1998/42 (86) International application number: PCT/EP94/01847 (21) Application number: 94920907.6 (87) International publication number: (22) Date of filing: 04.06.1994 WO 94/28868 (22.12.1994 Gazette 1994/28) (54) SKIN CARE COMPOSITION CONTAINING EMULSIFIED PETROLEUM JELLY HAUTPFLEGEZUSAMMENSETZUNG MIT EMULSIONIERTEM PETROLEUM COMPOSITION DE SOIN POUR LA PEAU CONTENANT DU PETROLATUM (84) Designated Contracting States: (72) Inventor: ZIEGLER, Philip Dale CH DE ES FR GB IT LI NL SE Oxford, CT 06478 (US) (30) Priority: 09.06.1993 US 74184 (74) Representative: Evans, Jacqueline Gail Victoria et al (43) Date of publication of application: Unilever pic 27.03.1996 Bulletin 1996/13 Patent Division Colworth House (73) Proprietors: Sharnbrook • UNILEVER PLC Bedford MK44 1 LQ (GB) London EC4P 4BQ (GB) Designated Contracting States: (56) References cited: GB EP-A-0103 910 WO-A-90/01323 • UNILEVER N.V. DE-A- 2 603 803 US-A- 4 760 096 3013 AL Rotterdam (NL) Designated Contracting States: • DATABASE WPI Week 8327, Derwent CH DE ES FR IT LI NL SE Publications Ltd., London, GB; AN 83-702267 & JP,A,58 088 304 (POLA KASEI) 26 May 1983 CO CO 10 CM o Note: Within nine months from the publication of the mention of the grant of the European patent, give r»- any person may notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in o a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. Q_ 99(1) European Patent Convention). LU Printed by Xerox (UK) Business Services 2.16.3/3.4 EP 0 702 548 B1 Description FIELD OF THE INVENTION 5 The invention concerns a cosmetic composition in emulsion form. BACKGROUND TO THE INVENTION Petroleum jelly, commercially available under the Vaseline® brand, has long been recognised as therapeutically 10 effective against dry skin. A major negative limiting use of petroleum jelly is the greasiness of this material. Petroleum jelly operates as a barrier but does not penetrate into the skin. Transfer of this material onto clothing, therefore, readily occurs. By contrast, water-based formulations, although often less effective, do not transfer to clothing and exhibit better feel properties. Not surprisingly, water-based cosmetic compositions such as aqueous lotions and creams have gar- nered the main share of the market. 15 An approach to providing the benefits of petroleum jelly while neutralising its greasy feel has been the preparation of aqueous petroleum jelly emulsions. Emulsif iers have been utilised to provide compatibility between aqueous and oil phases. Attempts at emulsif ication have not always been successful. Even when successful, the resultant product often fails to exhibit the skin protective properties of petroleum jelly. New and improved emulsifying systems would be highly desirable. 20 Illustrative of the art is US 4,760,096 (Sakai et al) which discloses a skin moisturising preparation that includes a phosphatide, at least one C10-C30 carboxylic acid sterol ester and at least one C6-C12 alkanoic triglyceride in a derma- tologically acceptable carrier. WO 90/01 323 (Bernstein) describes a composition for preventing dry skin based on a lipid concentrate combining three naturally-occurring lipid groups found in the stratum corneum. These groups include fatty acids, sterols (e.g. cholesterol) and sterol esters, and phospholipids and glycolipids (e.g. lecithin and ceramides). US 25 4,855,090 (Wallach) approaches the problem through the use of liposome technology. A nonaqueous lipophilic phase is combined with an aqueous phase under high shear mixing conditions to form the liposomes. Among the components included in the lipophilic phase are cholesterol and polyoxyethylene fatty ether surfactant while the aqueous phase con- tains phosphatides such as lecithin. EP 103 910 discloses skin conditioning compositions comprising an emulsion of petrolatum, water, an unsaturated 30 monoglyceride emulsif ier and a skin conditioning agent, preferably glycerine. A wide variety of other ingredients may be present, e.g. lecithin. DE 26 03 803 discloses that the stability of cosmetic emulsions can be improved by using a mix- ture of a fat keton and vegetable sterin as emulsifier for preparing water-in-oil emulsions. In this area of technology, further improvements are desirable with respect to skin conditioning and product stability. Accordingly, it is an object of the present invention to provide a cosmetic composition for skin which exhibits 35 improved moisturisation and provides greater protection against dry skin condition. It is a further object of the present invention to provide a cosmetic composition for skin which has improved storage stability. These and other objects of the present invention will become more readily apparent from the detailed description and examples which follow. 40 DISCLOSURE OF THE INVENTION Accordingly the invention provides a cosmetic composition comprising: 45 (i) from 5 to 80% by weight of water; (ii) from 0.5 to 30% by weight of petroleum jelly; (iii) from 0.01 to 10% by weight of sterol; (iv) from 0.001 to 5% by weight of a phosphatide; and (v) from 0.5 to 20% by weight of a Ci6-C22 alkanoic triglyceride. 50 The objects of the present invention, especially with respect to emulsion stability and skin moisturisation, are achieved with a water and oil emulsion that includes petroleum jelly, a sterol, a phosphatide and a Ci6-C22 alkanoic trig- lyceride. The emulsion will contain water in an amount from 5 to 80%, preferably from 10 to 50%, optimally between 20 and 55 40% by weight of the composition. A second essential element of the cosmetic composition according to the present invention is petroleum jelly. The amount of petroleum jelly will range from 0.5 to 30%, preferably between 3 and 20%, optimally 5 and 15% by weight of the composition. 2 EP 0 702 548 B1 A third essential element of the cosmetic composition according to the present invention is a sterol. Preferably the sterol is a 3p-sterol having a tail on the 1 7 position and having no polar groups. Illustrative of this category is cholesterol, sitosterol, stigmasterol and ergosterol. Cholesterol and soy sterol are preferred. A commercial source of soy sterol is a product known as General 122®, available from the Henkel Corporation, Ambler, PA. General 122® is a mixture of stig- 5 masterol, sitosterol and ergosterol. Cosmetic compositions according to the present invention will include the sterol in an amount from 0.01 to 10%, preferably between 0.05 and 2%, optimally between 0.05 and 1.5% by weight of the com- position. A further essential component of the cosmetic composition according to the present invention is a phosphatide. Example of suitable phosphatides are lecithin, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, 10 phosphatidyl inositol, diphosphatidyl glycerol and mixture thereof. Lysophosphoglycerides may also serve as the phos- phatide. Preferred among the foregoing list is lecithin. Amounts of the phosphatide will range from 0.001 to 5%, prefer- ably from 0.01 to 2%, optimally between 0.025 and 1% by weight of the composition. A further essential component of the cosmetic composition according to the present invention is a Ci6-C22 alkanoic triglyceride. Preferably the triglyceride will be based on a material whose major component is linoleic acid residues. 15 Sunflower seed oil is the preferred embodiment. Amounts of the triglyceride will range from 0.5 to 20%, preferably from 1 to 15%, optimally between 2 and 10% by weight of the composition. Another useful ingredient of the cosmetic composition according to the present invention is a gamma-linolenic acid. Borage seed oil (comprising 20% gamma-linolenic acid) is a desirable source for this ingredient. Amounts of the gamma-linolenic acid may conveniently range from 0.001 to 5%, preferably between 0.01 to 2% by weight of the com- 20 position. For improved lubricity, there may also be included one or more silicone oils or fluids which may be selected from a dimethyl polysiloxane, a methylphenyl polysiloxane and an alcohol-soluble silicone glycol copolymer. Preferred siloxanes include dimethyl polysiloxane (CTFA name: dimethicone), a polysiloxane end-blocked with trimethyl units and polydimethylcyclosiloxane, (CTFA name: cyclomethicone). The preferred siloxanes exhibit a viscosity from about 2 to 25 50 centistokes at 25°C. Amounts of the silicones can conveniently range from 0.5 to 60%, preferably between 1 and 30% by weight of the composition. A variety of oily emollients may be employed in the compositions of this invention. These emollients may be selected from hydrocarbon oils (e.g. mineral oils) Ci-C2o alkyl esters of fatty acids having 10 to 20 carbon atoms, Ci0- C22 fatty acids (e.g. stearic, palmitic, myristic and oleic acids), Ci0-C22 fatty alcohols (e.g. stearyl, palmityl, lauryl, myr- 30 istyl and oleyl alcohols), Ci0-C22 fatty alcohol ethers formed from ethoxylation of the alcohols with 1 -50 ethylene or pro- pylene oxide groups, C5-C50 polyhydric alcohol esters and combinations thereof. Amounts of the above listed emollients may range anywhere from 0.5 to 40% by weight of the total composition. Preferably the amounts of these emollients will range from 2 to 25%, optimally between 5 and 15% by weight. Humectants of the polyhydric alcohol-type may also be included in the compositions of this invention. The humect- 35 ant aids in increasing the effectiveness of the emollient, reduces scaling, stimulates removal of built-up scale and improves skin feel.