Game # Week Weekday Date Away Home Conference Location Notes 301 1 Thursday 9/2/2021 Ohio State Minnesota Big Ten TCF Bank Stadium, Minneapolis, MN 101 1 Friday 9/3/2021 North Carolina Virginia Tech ACC Lane Stadium/Worsham Field, Blacksburg, VA 102 1 Saturday 9/4/2021 Georgia Clemson ACC Bank of America Stadium, Charlotte, NC Neutral Site 302 1 Saturday 9/4/2021 Indiana Iowa Big Ten Kinnick Stadium, Iowa City, IA 201 1 Saturday 9/4/2021 Stanford Kansas State Big 12 AT&T Stadium, Arlington, TX Neutral Site 303 1 Saturday 9/4/2021 West Virginia Maryland Big Ten Capital One Field at Maryland Stadium, College Park, MD 103 1 Saturday 9/4/2021 Alabama Miami ACC Mercedes-Benz Stadium, Atlanta, GA Neutral Site 304 1 Saturday 9/4/2021 Michgan State Northwestern Big Ten Ryan Field, Evanston, IL 305 1 Saturday 9/4/2021 Oregon State Purdue Big Ten Ross-Ade Stadium, West Lafayette, IN 306 1 Saturday 9/4/2021 Penn State Wisconsin Big Ten Camp Randall Stadium, Madison, WI 104 1 Sunday 9/5/2021 Notre Dame Florida State ACC Doak Campbell Stadium, Tallahassee, FL 105 1 Monday 9/6/2021 Ole Miss Louisville ACC Mercedes-Benz Stadium, Atlanta, GA Neutral Site 401 2 Saturday 9/11/2021 Texas Arkansas SEC Razorback Stadium, Fayetteville, AR 202 2 Saturday 9/11/2021 Iowa Iowa State Big 12 MidAmerican Energy Field at Jack Trice Stadium, Ames, IA 402 2 Saturday 9/11/2021 Missouri Kentucky SEC Kroger Field, Lexington, KY 403 2 Saturday 9/11/2021 NC State Mississippi State SEC Davis Wade Stadium at Scott Field, Starkville, MS 307 2 Saturday 9/11/2021 Oregon Ohio State Big Ten Ohio Stadium, Columbus, OH 203 2 Saturday 9/11/2021 California TCU Big 12 Amon G. Carter Stadium, Fort Worth, TX 404 2 Saturday 9/11/2021 Pittsburgh Tennessee SEC Neyland Stadium, Knoxville, TN 106 2 Saturday 9/18/2021 Rutgers Syracuse ACC Carrier Dome, Syracuse, NY 107 2 Saturday 9/18/2021 Illinois Virginia ACC David A. Harrison III Field at Scott Stadium, Charlottesville, VA 108 3 Saturday 9/18/2021 Georgia Tech Clemson ACC Memorial Stadium , Clemson, SC 109 3 Saturday 9/18/2021 Northwestern Duke ACC Wallace Wade Stadium, Durham, NC 405 3 Saturday 9/18/2021 Alabama Florida SEC Ben Hill Griffin Stadium, Gainesville, FL 406 3 Saturday 9/18/2021 South Carolina Georgia SEC Sanford Stadium, Athens, GA 308 3 Saturday 9/18/2021 Maryland Illinois Big Ten Memorial Stadium , Champaign, IL 204 3 Saturday 9/18/2021 Baylor Kansas Big 12 David Booth Kansas Memorial Stadium, Lawrence, KS 110 3 Saturday 9/18/2021 Michigan State Miami ACC Hard Rock Stadium, Miami Gardens, FL 111 3 Saturday 9/18/2021 Virginia North Carolina ACC Kenan Stadium, Chapel Hill, NC 113 3 Saturday 9/18/2021 Purdue Notre Dame ACC Notre Dame Stadium, Notre Dame, IN 205 3 Saturday 9/18/2021 Nebraska Oklahoma Big 12 Memorial Stadium , Norman, OK 310 3 Saturday 9/18/2021 Auburn Penn State Big Ten Beaver Stadium, University Park, PA 407 3 Saturday 9/18/2021 Stanford Vanderbilt SEC Vanderbilt Stadium, Nashville, TN 112 3 Saturday 9/18/2021 Florida State Wake Forest ACC Truist Field, Winston-Salem, NC 206 3 Saturday 9/18/2021 Virginia Tech West Virginia Big 12 Mountaineer Field at Milan Puskar Stadium, Morgantown, WV 114 4 Friday 9/24/2021 Wake Forest Virginia ACC David A. Harrison III Field at Scott Stadium, Charlottesville, VA 408 4 Saturday 9/25/2021 Texas A&M Arkansas SEC AT&T Stadium, Arlington, TX Neutral Site 207 4 Saturday 9/25/2021 Iowa State Baylor Big 12 McLane Stadium, Waco, TX 115 4 Saturday 9/25/2021 Missouri Boston College ACC Alumni Stadium , Chestnut Hill, MA 116 4 Sunday 9/25/2021 Kansas Duke ACC Wallace Wade Stadium, Durham, NC 409 4 Saturday 9/25/2021 Tennessee Florida SEC Ben Hill Griffin Stadium, Gainesville, FL 117 4 Monday 9/25/2021 Louisville Florida State ACC Doak Campbell Stadium, Tallahassee, FL 118 4 Tuesday 9/25/2021 North Carolina Georgia Tech ACC Mercedes-Benz Stadium, Atlanta, GA 311 4 Saturday 9/25/2021 Rutgers Michigan Big Ten Michigan Stadium, Ann Arbor, MI 312 4 Saturday 9/25/2021 Nebraska Michigan State Big Ten Spartan Stadium, East Lansing, MI 410 4 Saturday 9/25/2021 LSU Mississippi State SEC Davis Wade Stadium at Scott Field, Starkville, MS 119 4 Thursday 9/25/2021 Clemson NC State ACC Carter-Finley Stadium, Raleigh, NC 208 4 Saturday 9/25/2021 West Virginia Oklahoma Big 12 Memorial Stadium , Norman, OK 209 4 Saturday 9/25/2021 Kansas State Oklahoma State Big 12 Boone Pickens Stadium, Stillwater, OK 313 4 Saturday 9/25/2021 Illinois Purdue Big Ten Ross-Ade Stadium, West Lafayette, IN 411 4 Saturday 9/25/2021 Kentucky South Carolina SEC Williams-Brice Stadium, Columbia, SC 210 4 Saturday 9/25/2021 Texas Tech Texas Big 12 DKR-Texas Memorial Stadium, Austin, TX 412 4 Saturday 9/25/2021 Georgia Vanderbilt SEC Vanderbilt Stadium, Nashville, TN 314 4 Saturday 9/25/2021 Notre Dame Wisconsin Big Ten Soldier Field, Chicago, IL 120 5 Thursday 9/30/2021 Virginia Miami ACC Hard Rock Stadium, Miami Gardens, FL 413 5 Saturday 10/2/2021 Ole Miss Alabama SEC Bryant-Denny Stadium, Tuscaloosa, AL 121 5 Saturday 10/2/2021 Boston College Clemson ACC Memorial Stadium , Clemson, SC 122 5 Saturday 10/2/2021 Syracuse Florida State ACC Doak Campbell Stadium, Tallahassee, FL 414 5 Saturday 10/2/2021 Arkansas Georgia SEC Sanford Stadium, Athens, GA 123 5 Saturday 10/2/2021 Pittsburgh Georgia Tech ACC Bobby Dodd Stadium, Atlanta, GA 211 5 Saturday 10/2/2021 Kansas Iowa State Big 12 MidAmerican Energy Field at Jack Trice Stadium, Ames, IA 212 5 Saturday 10/2/2021 Oklahoma Kansas State Big 12 Bill Snyder Family Stadium, Manhattan, KS 415 5 Saturday 10/2/2021 Florida Kentucky SEC Kroger Field, Lexington, KY 416 5 Saturday 10/2/2021 Auburn LSU SEC Tiger Stadium , Baton Rouge, LA 315 5 Saturday 10/2/2021 Iowa Maryland Big Ten Capital One Field at Maryland Stadium, College Park, MD 417 5 Saturday 10/2/2021 Tennessee Missouri SEC Memorial Stadium/Faurot Field, Columbia, MO 316 5 Saturday 10/2/2021 Northwestern Nebraska Big Ten Memorial Stadium , Lincoln, NE 124 5 Saturday 10/2/2021 Duke North Carolina ACC Kenan Stadium, Chapel Hill, NC 213 5 Saturday 10/2/2021 Baylor Oklahoma State Big 12 Boone Pickens Stadium, Stillwater, OK 317 5 Saturday 10/2/2021 Indiana Penn State Big Ten Beaver Stadium, University Park, PA 318 5 Saturday 10/2/2021 Minnesota Purdue Big Ten Ross-Ade Stadium, West Lafayette, IN 319 5 Saturday 10/2/2021 Ohio State Rutgers Big Ten SHI Stadium, Piscataway, NJ 214 5 Saturday 10/2/2021 Texas TCU Big 12 Amon G. Carter Stadium, Fort Worth, TX 418 5 Saturday 10/2/2021 Mississippi State Texas A&M SEC Kyle Field, College Station, TX 125 5 Saturday 10/2/2021 Louisville Wake Forest ACC Truist Field, Winston-Salem, NC 215 5 Saturday 10/2/2021 Texas Tech West Virginia Big 12 Mountaineer Field at Milan Puskar Sta 320 5 Saturday 10/2/2021 Michigan Wisconsin Big Ten Camp Randall Stadium, Madison, WI 419 6 Saturday 10/9/2021 Georgia Auburn SEC Jordan-Hare Stadium, Auburn, AL 216 6 Saturday 10/9/2021 West Virginia Baylor Big 12 McLane Stadium, Waco, TX 126 6 Saturday 10/9/2021 Georgia Tech Duke ACC Wallace Wade Stadium, Durham, NC 420 6 Saturday 10/9/2021 Vanderbilt Florida SEC Ben Hill Griffin Stadium, Gainesville, FL 321 6 Saturday 10/9/2021 Wisconsin Illinois Big Ten Memorial Stadium , Champaign, IL 322 6 Saturday 10/9/2021 Penn State Iowa Big Ten Kinnick Stadium, Iowa City, IA 421 6 Saturday 10/9/2021 LSU Kentucky SEC Kroger Field, Lexington, KY 127 6 Saturday 10/9/2021 Virginia Louisville ACC Cardinal Stadium, Louisville, KY 323 6 Saturday 10/9/2021 Michigan Nebraska Big Ten Memorial Stadium , Lincoln, NE 128 6 Saturday 10/9/2021 Florida State North Carolina ACC Kenan Stadium, Chapel Hill, NC 324 6 Saturday 10/9/2021 Maryland Ohio State Big Ten Ohio Stadium, Columbus, OH 422 6 Saturday 10/9/2021 Arkansas Ole Miss SEC Vaught-Hemingway Stadium, Oxford, MS 325 6 Saturday 10/9/2021 Michigan State Rutgers Big Ten SHI Stadium, Piscataway, NJ 129 6 Saturday 10/9/2021 Wake Forest Syracuse ACC Carrier Dome, Syracuse, NY 423 6 Saturday 10/9/2021 South Carolina Tennessee SEC Neyland Stadium, Knoxville, TN 217 6 Saturday 10/9/2021 Oklahoma Texas Big 12 Cotton Bowl, Dallas, TX 424 6 Saturday 10/9/2021 Alabama Texas A&M SEC Kyle Field, College Station, TX 218 6 Saturday 10/9/2021 TCU Texas Tech Big 12 Jones AT&T Stadium, Lubbock, TX 130 6 Saturday 10/9/2021 Notre Dame Virginia Tech ACC Lane Stadium/Worsham Field, Blacksburg, VA 131 7 Friday 10/15/2021 Clemson Syracuse ACC Carrier Dome, Syracuse, NY 425 7 Saturday 10/16/2021 Auburn Arkansas SEC Razorback Stadium, Fayetteville, AR 219 7 Saturday 10/16/2021 BYU Baylor Big 12 McLane Stadium, Waco, TX 132 7 Saturday 10/16/2021 NC State Boston College ACC Alumni Stadium , Chestnut Hill, MA 426 7 Saturday 10/16/2021 Kentucky Georgia SEC Sanford Stadium, Athens, GA 326 7 Saturday 10/16/2021 Michigan State Indiana Big Ten Memorial Stadium , Bloomington, IN 327 7 Saturday 10/16/2021 Purdue Iowa Big Ten Kinnick Stadium, Iowa City, IA 220 7 Saturday 10/16/2021 Texas Tech Kansas Big 12 David Booth Kansas Memorial Stadium, Lawrence, KS 221 7 Saturday 10/16/2021 Iowa State Kansas State Big 12 Bill Snyder Family Stadium, Manhattan, KS 427 7 Saturday 10/16/2021 Florida LSU SEC Tiger Stadium , Baton Rouge, LA 328 7 Saturday 10/16/2021 Nebraska Minnesota Big Ten TCF Bank Stadium, Minneapolis, MN 428 7 Saturday 10/16/2021 Alabama Mississippi State SEC Davis Wade Stadium at Scott Field, Starkville, MS 429 7 Saturday 10/16/2021 Texas A&M Missouri SEC Memorial Stadium/Faurot Field, Columbia, MO 133 7 Saturday 10/16/2021 Miami North Carolina ACC Kenan Stadium, Chapel Hill, NC 329 7 Saturday 10/16/2021 Rutgers Northwestern Big Ten Ryan Field, Evanston, IL 222 7 Saturday 10/16/2021 TCU Oklahoma Big 12 Memorial Stadium , Norman, OK 430 7 Saturday 10/16/2021 Vanderbilt South Carolina SEC Williams-Brice Stadium, Columbia, SC 431 7 Saturday 10/16/2021 Ole Miss Tennessee SEC Neyland Stadium, Knoxville, TN 223 7 Saturday 10/16/2021 Oklahoma State Texas Big 12 DKR-Texas Memorial Stadium, Austin, TX 134 7 Saturday 10/16/2021 Duke Virginia ACC David A.