CURRICULUM VITAE NAME: David Michael DeMarini LOCATION: Integrated Systems Toxicology Division (B105-03), U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA TEL 1-919-541-1510, FAX 1-919-541-0694, E-mail: [email protected] CITIZENSHIP: United States of America EDUCATION: Illinois State University, Normal, IL, B.S., Biological Sciences, 1972 M.S., Biological Sciences, 1974 Ph.D., Biological Sciences, 1980 RESEARCH EXPERIENCE 1974 - 1975 Assistant Research Microbiologist, U.S. Department of Agriculture, Northern Regional Research Center, Peoria, IL 1975 - 1979 Research Assistantship, Illinois State University, Normal, IL 1980 - 1982 Postdoctoral Investigator, Biology Division, Oak Ridge National Laboratory, Oak Ridge, TN 1983 - 1984 Research Geneticist, Oak Ridge Associated Universities, Cellular and Genetic Toxicology Branch, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 1985 - Present Genetic Toxicologist, Genetic and Cellular Toxicology Branch, Integrated Systems Toxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle, North Carolina 27711, USA TEACHING EXPERIENCE 1972 - 1974 Teaching Assistantship, Illinois State University, Normal, IL 1991 - 2000 Adjunct Associate Professor, UNC 2001 - Present Adjunct Professor, Department of Environmental Science and Engineering, School of Public Health, University of North Carolina, Chapel Hill, NC GRADUATE STUDENTS TRAINED 1. Jessie G. Levine, Ph.D., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, May, 1992. "Factors Influencing Mutation Spectra at the hisD3052 Allele of Salmonella typhimurium" 2. Carolyn F. Felton, M.S., Department of Biology, North Carolina Central University, Durham, May, 1993. "Mutation Spectra of an Organic Extract of a Chlorinated Drinking Water Sample in Salmonella typhimurium" 3. Maria S. Taylor, M.S.P.H., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, July, 1993. "Evaluation of the Additivity Assumption Using the Spiral Salmonella Mutagenicity Assay with Binary Combinations of Single Chemicals and Complex Mixtures" 4. George M. Woodall Jr., Ph.D., Department of Toxicology, North Carolina State University, Raleigh, May, 1996. "Effects of Dietary Casein Levels on the Activation and Metabolism of Promutagens by Rat Hepatic S9, Microsomes, and Cytosol" 5. Daniel T. Shaughnessy, M.S.P.H., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, December, 1999. “Mutation Spectra of the Drinking Water Mutagen 3-Chloro-4-Methyl-5-Hydroxy-2(5H)-Furanone (MCF) in Salmonella TA100 and TA104: Comparison to MX” 6. Bijit Kundu, M.S., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, August, 2001. “Mutagenicity in Salmonella of Nitrohalomethanes, a Recently Recognized Class of Disinfection By-Products: Comparison to Halomethanes” 7. Courtney Granville, M.S.P.H., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, April, 2002, “Genotoxicity of Source Water Contaminants 1,3-Dichloropropane, 2,2-Dichloropropane, and 1,1-Dichloropropene in Salmonella, the E. coli, Prophage-Induction Assay, and Human Lymphoblastoid Cells” 8. Daniel T. Shaughnessy, Ph.D., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, September, 2002, “Effects of the Antimutagens Vanillin and Cinnamaldehyde on Spontaneous Mutation in E. coli lacI strains and Salmonella TA104 and on Global Gene Expression in Human HepG2 Cells” 9. Mina Kato, Ph.D., Department of Epidemiology, University of North Carolina at Chapel Hill, anticipated for May, 2003, “Urinary Biomarkers in Charcoal Workers Exposed to Wood Smoke in Bahia State, Brazil” 10. Raju Y. Prasad, Ph.D., Department of Environmental Science and Engineering, University of North Carolina at Chapel Hill, June, 2013, “Genotoxicity of Titanium Dioxide Nanoparticles” POSTDOCTORAL INVESTIGATORS TRAINED 1. Dr. Douglas A. Bell (USA, 1988-1990), currently Head of the Environmental Genomics Group, Laboratory of Molecular Genetics, NIEHS, RTP, NC 2. Dr. Amal Abu-Shakra (Lebanon, 1990-1993), Professor, Biology Department, North Carolina Central University, Durham, NC 3. Dr. Takeshi Ohe (Japan, 1998-1999), currently Professor, Kyoto Women’s University, Kyoto, Japan 4. Dr. Defa Tian (China, 1998-2001), currently on staff at Georgetown University, Washington, DC 5. Dr. Stefano Landi (Italy, 1998-2000), currently Assistant Professor, Biology Dept., University of Pisa, Italy 6. Dr. Kunihiro Funasaka (Japan, 2002-2003), currently Chief Engineer, Osaka City Institute of Public Health, Osaka, Japan) 7. Dr. William O. Ward (USA, 2005-2007), currently Staff Scientist, NHEERL, US EPA, RTP, NC 8. Dr. Carol D. Swartz (USA, 2005-2007), currently a Staff Scientist, Integrated Laboratory Systems, Durham, NC 9. Dr. Jin-Sung Ra (Korea, 2007-2008), currently a research associate, Switzerland 10. Dr. Esra Mutlu (Turkey, 2011-2013), currently research associate at UNC, Chapel Hill, NC 11. Dr. Jose Zavala (USA, 2014-present) HONORS 1. Outstanding Ph.D. Student of the Year, Phi Sigma Society, 1979 2. Outstanding Young Alumni Award, Illinois State University, 1990 2. Honorable Mention, Scientific and Technological Achievement Award (STAA), US EPA, 1994, for "Mutagenicity and Chemical Analysis of Emissions from the Open Burning of Scrap Rubber Tires" 3. Level II Award, Scientific and Technological Achievement Award (STAA), US EPA, 1997, for "Elucidating Molecular Features of the Salmonella Assay and Mutation Spectra of Complex Environmental Mixtures" 4. Alumni Achievement Award, Illinois State University, 2000. 5. Environmental Mutagen Society Education and Student Member Committee Award, 2002. 6. Level III Award, Scientific and Technological Achievement Award (STAA), US EPA, 2003, for “Demonstrating that Mutations in Tumors Reflect Exposure to Environmental Mutagens and Carcinogens” 4 7. Level I Award (highest award), Scientific and Technological Achievement Award (STAA), US EPA, 2004, for “Identifying the Ultimate Genotoxic Forms of Arsenic and the Class of Mutations They Induce.” 8. Level III Award, Scientific and Technological Achievement Award (STAA), US EPA, 2005, for Setting Standards for Conducting Multidisciplinary Environmental Effects Studies of Complex Particulate Mixtures” 9. Alumni Hall of Fame Award, Illinois State University, 2006 10. US EPA, NHEERL Goal 3 Award for “Leadership in the Environmental Research Community” 2006 11. Level II Scientific and Technological Achievement Award (STAA), US EPA, 2008, for “Review of Genotoxicity and Carcinogenicity of Drinking Water Disinfection By-products” 12. Level II Scientific and Technological Achievement Award (STAA), US EPA, 2008, for “Review of Health Effects of Swimming Pool Water” 13. U.S. EPA, Office of Research and Development (ORD) 2008 “Science Communications Award” 14. The 2011 Alexander Hollaender Award from the Environmental Mutagen Society 15. A 2011 Level III Scientific and Technological Achievement Award (STAA), US EPA for “A Review of the Salmonella Mutagenicity Assay and How it Informs the Development of 21st Century Toxicology Assays” 16. A 2011 Honorable Mention Scientific and Technological Achievement Award (STAA) for “The First Comprehensive Characterization of DBPs in Indoor Swimming Pool Water and Their Role in the Water's Mutagenicity” EDITORSHIPS AND EDITORIAL BOARDS EDITOR Mutation Research—Reviews (Editor 1998-present) EMS Newsletter (Co-Editor 1988-1991) Environmental and Molecular Mutagenesis (Book Review Editor 1989-1993) EDITORIAL BOARDS Mutation Research (1985-1997) Environmental and Molecular Mutagenesis (1984-1989; 1993-present) Mutagenesis (1992-1995; 2006-2013) Environmental Health Perspectives (1988-1993) 5 Teratogenesis Carcinogenesis and Mutagenesis (1990-1992) EMS Newsletter (1986-1988) Pan-African Environmental Mutagen Society Newsletter (1994-present) Environmental Mutagens and Carcinogens (2001-2005) Genes and Environment (2006-present) Frontiers in Cancer Epidemiology and Prevention (2011-present) PROFESSIONAL APPOINTMENTS Member, Neurospora panel, EPA Gene-Tox Data Review Committee, 1980-1982 Member Neurospora panel, EPA Aneuploidy Data Review Committee, 1984-1985 Member, Working Group of IARC Monograph Vol. 38 on the Carcinogenicity of Tobacco Smoke, International Agency for Research on Cancer, Lyon, France, 1985 Secretary and Member, Board of Directors, Genotoxicity and Environmental Mutagen Society (GEMS), 1983-1985 Vice-President, GEMS, 1987-1988 President, GEMS, 1988-1989 Councilor, Environmental Mutagen Society, 1988-1991 Chair, Working Group on Hazard Identification, Comparative Risk Assessment Associated with Exposure of Human and Nonhuman Biota to Genotoxic Agents and Ionizing Radiation, International Commission for Protection Against Environmental Mutagens and Carcinogens (ICPEMC), December 7-14, 1990 at Belleville, France; May 20-23,1991 at Harpers Ferry, WV; October 21-23, 1991 at Livermore, CA; January 11- 13, 1992 at Belleville, France Member, Working Group on Hazard Identification, Drinking Water and Health in the Year 2000 Workshop, Breckenridge, CO, July 14-17, 1991 Chair, Future Directions Committee (1992-1993), Alexander Hollaender Fund for International Programs (1993-1995), and Publications Policy Committee