2EPORT Table of Contents Boards . 5 Group Leaders - Core Sector . 6 Research Groups - Outer Circle . 8 Concept and Structure of the IZN . 13 IZN Budget and grant giving bodies . 19 Collaborations of IZN Members . 20 Research Profiles - Core Sector . 25 Hilmar Bading . 26 Roland Brandt . 28 Francesca Ciccolini . 30 Uwe Ernsberger . 32 Hans-Hermann Gerdes . 34 Siegfried Mense . 36 Hannah Monyer . 38 Andrei Rozov . 40 Horst Simon . 42 Jacqueline Trotter . 44 Kerry L. Tucker . 46 Klaus Unsicker . 48 William Wisden . 50 Research Profiles - Outer Circle . 53 Bernd W. Böttiger . 54 Andreas Draguhn . 55 Herta Flor . 56 Rainer Friedrich . 57 Harald Hutter . 58 Marika Kiessling . 59 Joachim Kirsch . 60 Ulrich Misgeld . 61 Stefan Offermanns . 62 G. Elisabeth Pollerberg . 63 Klaus Sartor . 64 Johannes Schröder . 65 Markus Schwaninger . 66 Peter H. Seeburg . 67 Jeremy C. Smith . 68 Rainer Spanagel . 69 Brigitte Wildemann . 70 Joachim Wittbrodt . 71 Central Facilities . 74 IZN Teaching Program . 76 Publications of IZN members, 2001-2002 . 87 Symposia and Seminars . 95 Guest Scientists 2001-2002 . 110 Diploma and Doctoral Theses . 111 Boards Boards Board of Directors Hilmar Bading, Professor Dr. Hannah Monyer, Professor Dr. Klaus Unsicker, Professor Dr. (acting director) Scientific Advisory Board Prof. Dr. Adriano Aguzzi, Zürich Prof. Yehezkel Ben-Ari, M.D, Ph.D., Marseille Prof. Dr. Anders Björklund, Lund Dr. Magdalena Götz, München Prof. Nathaniel Heintz, Ph.D., New York Prof. Dr. Arthur Konnerth, München Prof. Mark Mattson, M.D., Ph.D., Baltimore Prof. Dr. Hans-Christian Pape, Magdeburg Prof. Mart Saarma, Ph.D., Helsinki Prof. Stephen G. Waxman, M.D., Ph.D., New Haven 5 Group Leaders - Core Sector Group Leaders - Core Sector Hilmar Bading, Professor Dr. Uwe Ernsberger, Privatdozent Dr. Development of nerve cells and generation of Neuronal calcium signaling neuronal diversity A +49-(0)6221-548218 A +49-(0)6221-548344 E +49-(0)6221-546700 E +49-(0)6221-545604 K [email protected] K [email protected] Roland Brandt, Professor Dr. (until 11/02) Hans-Hermann Gerdes, Privatdozent Dr. Cytoskeletal mechanisms during neuronal devel- Membrane traffic in neuronal cell systems opment and degeneration A +49-(0)541-969 2338 A +49-(0)6221-548317 E +49-(0)541-969 2354 E +49-(0)6221-546700 K [email protected] K [email protected] Roberto Bruzzone, Ph.D., INSERM guest group Dieter Langosch, Privatdozent Dr. (until 07/01) Assembly and function of membrane-embedded Cell communication by gap junction coupling protein domains A +49-(0)6221-562417 A +49-(0)8161-713500 E +49-(0)6221-561397 E +49-(0)-8161-714404 K [email protected] K [email protected] Francesca Ciccolini, Ph.D. Siegfried Mense, Professor Dr. Peripheral and spinal mechanisms of muscle pain; Neural stem cell development and role of calcium neurotransmitters involved in the neuromodula- signaling in neural precursor differentiation tion of the reflex bladder A +49-(0)6221-548696 A +49-(0)6221-544193 E +49-(0)6221-546700 E +49-(0)6221-546071 K [email protected] K [email protected] 6 Group Leaders - Core Sector Hannah Monyer, Professor Dr. Jacqueline Trotter, Ph.D. (until 03/03) Molecular cell biology of neuron-glia interaction Neuronal synchrony and plasticity and myelination A +49-(0)6221-562400 A +49-(0)6131-3922879 E +49-(0)6221-561397 E +49-(0)6131-3923840 K [email protected] K [email protected] Anne Regnier-Vigouroux (until 12/00) Kerry Tucker, Ph.D. (as of 07/03) Control of peripheral nerve outgrowth in embry- Immune competence of astrocytes and microglia onic mouse development A +49-(0)6221 42 46 13 A +41-(0)61-697 5019 E +49-(0)6221 42 49 62 E +41-(0)61-697 3976 K [email protected] K [email protected] Andrei Rozov, Dr. Klaus Unsicker, Professor Dr. TGF-ßs, FGFs and neurotrophins in neural deve- Mechanisms of short lasting synaptic plasticity lopment and functions A +49-(0)6221-562419 A +49-(0)6221-548227 E +49-(0)6221-541397 E +49-(0)6221-545604 K [email protected] K [email protected] Horst Simon, Ph.D. William Wisden, Ph.D. Development of midbrain dopaminergic neurons Inhibitory ion channels A +49-(0)6221-548342 A +49-(0)6221- 562403, -2411 E +49-(0)6221-545605 E +49-(0)6221-561397 K [email protected] K [email protected] 7 Research Groups - Outer Circle Research Groups - Outer Circle Department of Physiology and Pathophysiology Andreas Draguhn ZMBH Inhibitory synapses and network oscillations Konrad Beyreuther Alzheimer’s disease: etiology, physiological Wolfgang Kuschinsky and pathophysiological functions of APP and Proteomics and stroke presenilins Ulrich Misgeld Tobias Hartmann Plasticity of GABAA receptor mediated inhibi- Cellular regulation mechanisms of protein tion degradation and protein transport in Alz- heimer’s and Parkinson disease Horst Seller Autonomic control of cardiovascular functions Joachim Herz Lipids and their receptors in neurodegene- Department of Pharmacology.