Volume 3 Naumber 1 March 2016 ISSN 2071-2324 BANGLADESH Jounrnal of HEPATOLOGY Official Journal of ASSOCIATION FOR THE STUDY OF LIVER Association for the Study of Liver Diseases Bangladesh DISEASES BANGLADESH (National Association of Hepatologists of Bangladesh) Bangladesh Journal of Hepatology Bangladesh Journal of Hepatology Official Journal of Association for the Study of Liver Diseases Bangladesh (National body of Hepatologists of Bangladesh) Correspondence Room # 506, 4th floor Block # D Bangabandhu Sheikh Mujib Medical University Shahbag, Dhaka-1000 Email: [email protected], [email protected] Vol. 3 No. 1 01 Bangladesh Journal of Hepatology Bangladesh Journal of Hepatology Editorial Board Editor in Chief Professor Salimur Rahman Associate Editor Dr. Ayub Al Mamun Dr. Chitto Ranjan Debnath Dr. Faroque Ahmed Dr. K. M. J. Zaki Dr. Mamun-Al-Mahtab Dr. Md. Jasmshed Alam Khan Assistant Editor Dr. Harun Or Rashid Dr. Md. Fazal Karim Dr. Md. Izazul Haque Dr. Muhammad Mahbub Hossain Editorial Board Dr. Abu Saleh Md. Sadequl Islam Dr. Abul Barkat Muhammad Adnan Dr. Ahmed Lutful Moben Dr. Amalendu Bhattacharyya Dr. Arun Jyoti Tarafder Dr. Forhad Hossain Md. Shahed Dr. Golam Mashud Dr. Kutub Uddin Mollick Dr. Md. Abdur Rahim Dr. Md. Ashraful Alam Dr. Md. Dalil Uddin Dr. Md. Jahangir Alam Sarker Dr. Md. Zia Hayder Bosunia Dr. Mohammad Faiz Ahmad Khondaker Dr. Provat Kumar Podder Dr. Shamsul Kabir Dr. Sheikh Mohammad Noor-E-Alam Dr. Syed Abul Foez 02 Vol. 3 No. 1 Bangladesh Journal of Hepatology Volume 3 Number 1 Content Editorial Page Bangladesh Journal of Hepatology: Blown in the winds of heterogeneity and plurality 05 Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab Original Articles Causes of jaundice in clinical practice: An observation at Brahmanbaria 07 Forhad Hossain Mohammad Shahed, Mamun Al Mahtab, Mohammad Fakhrul Islam Khaled, Mohammad Abul Fayaz, Ashiqur Rahman Khan Prevalence of Hepatitis B and Hepatitis C in Rural Population of Bangladesh 10 Mohammad Izazul Hoque, Mohammad Belalul Islam, Mostafa Kamal Azad Socio-demographic profile of non alcoholic fatty liver disease of 100 patients attended SBMCH Barisal 15 Golam Mashud, Jamsed Alom, Swapon Kumar Sarkar, Anwar Hossain, Amolendu Bhattacharia, Al Mamun Hossain Upper gastrointestinal endoscopic findings in adults at Comilla Medical College & Hospital, Bangladesh 20 Mohammad Forhad Abedin, Mohammad Asaduzzaman Lashkar, Mohammad Shah Jamal, Mohammad Belalul Islam, Mohammad Izazul Haque, Mohammad Abdur Rob Sarkar Review Articles Hepatic hydrothorax: Challenge for Hepatologist 25 Syed Abul Foez, Mohammad Abdur Rahim, Sheikh Mohammad Noor-E-Alam, Mohammad Ashraful Alam, AKM Shoab, Swapan Kumar Singha, Joy Vargese, Chandan Kumar, Mamun-Al-Mahtab, Salimur Rahman, Ziaur Rahman Chowdhury Brief Review Current strategies in the management of hepatocellular carcinoma 31 Premashish Kar Case Reports A case of occult hepatitis B virus infection and hepatocellular carcinoma from Bangladesh 34 Ponkaj Kumar Naha, Mamun-Al-Mahtab, Sarkar Mohammad Shahadat Hossain, Rokshana Begum, Abul Hayet Manik, Debraj Malakar, Partho Pratic Roy, Ayub Al Mamun, Salimur Rahman Vol. 3 No. 1 03 Bangladesh Journal of Hepatology Abstracts of LIVERCON 2016 Association of portal vein tumor thrombus in hepatitis B related hepatocellular carcinoma 36 Abu Saleh Mohammad Sadequl Islam, Mamun Al Mahtab, Ayub Al Mamun, Sheikh Mohammad Fazle Akbar, Mohammad Kamal Hossain, Zia Hayder Bosunia, Salimur Rahman Metabolic syndrome is a good predictor for diagnosing non-alcoholic steatohepatitis. 37 Sheikh Mohammad Noor-E-Alam, Ahmed Lutful Moben, Zia Hayder Basunia, Amalendu Bhattacharyya, Abdur Rahim, Syed Abul Foez, Mohammad Shahed Ashraf, Faiz Ahmad Khandoker, Md. Jahangir Alam Sarker, Abu Saleh Mohammad Sadequl Islam, Mohammad Forhad Abedin, Utpal Das Gupta, Mohammad Jahangir Kabir, Mamun-Al-Mahtab, Salimur Rahman Upper gastrointestinal endoscopic findings in adults at Comilla Medical College & Hospital, Bangladesh 38 Mohammad Forhad Abedin, Mohammad Asaduzzaman Lashkar, Mohammad Shah Jamal, Mohammad Belalul Islam, Mohammad Izazul Haque, Mohammad Abdur Rob Sarkar Causes of jaundice in clinical practice: An observation at Brahmanbaria 39 Forhad Hossain Mohammad Shahed, Mamun Al Mahtab, Mohammad Fakhrul Islam Khaled, Mohammad Abul Fayaz, Ashiqur Rahman Khan Non favorable genotype is predominant at IL28B rs12979860 polymorphism in hepatitis B related hepatocellular carcinoma 40 Abu Saleh Mohammad Sadequl Islam, Mamun Al Mahtab, Ayub Al Mamun, Sheikh Mohammad Fazle Akbar, Mohammad Eunus Ali, Zia Hayder Bosunia, Salimur Rahman Life Sketch of Professor Baruch Samuel Blumberg 41 Email from Professor Baruch Samuel Blumberg 43 Brief Introduction of Dr. Nagaraja Rao Padaki: Blumberg Orator 2016 44 List of Blumberg Orators 45 04 Vol. 3 No. 1 Bangladesh Journal of Hepatology Editorial Bangladesh Journal of Hepatology: Blown in the winds of heterogeneity and plurality Sheikh Mohammad Fazle Akbar1, Mamun Al Mahtab2 1Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan, 2Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Correspondence to Dr. Sheikh Mohammad Fazle Akbar Principal Investigator, Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan. Email <[email protected]> Transmission of knowledge, acceptance of new and about liver and allied disciplines of the world and novel ideas and discarding false but tempting concepts Asia-Pacific region with Bangladesh; thus it is acting as constitute the backbone of social and scientific media to translate all new information palatable to developments of modern-day society. This is especially Bangladeshi hepatologists and physicians of relevant in the context of liver and its pathologies as multidisciplinary positions. A journal is judged by its more than one halves of world population represent the longevity and also persistent improvement of its causality of different hepatotrophic viruses that infects qualitative inceptions. Bangladesh Journal of the liver, disrupt its microenvironments, and induce Hepatology has entered the stage of adolescence after long-term complications like the deadly term of liver crossing the steps of new born, infant and child. The cirrhosis and liver cancer. The impacts and implications future is waiting to accept it as an “ADULT” in the world of these diseases are more pronounced in developing of modern publication. countries, like Bangladesh with limited resources. The The uninterrupted publication of this journal has been primary responsibility of tackling liver and its diseases possible due enormous efforts of its leadership because in Bangladesh has been shouldered by Association for most of the journal of developing countries undergo the Study of Liver Diseases Bangladesh (ASLDB) with spontaneous apoptosis soon after their sailings. Now, it the assistance of its members and patrons. However, is the time to make qualitative improvement of the another major responsibility remains regarding the journal in global perspective. Various clinical researches means of transmitting evolving knowledges about liver and case-control studies have been accomplished in diseases to the members of ASLDB and also to other Bangladesh. Also, new and novel therapeutic allied physicians and medical service delivery approaches have been tested in Bangladesh in last one personnel. This noble responsibility has mainly been decade. ASLDB is also credited for being the sole accomplished by a publication named “Bangladesh sponsor of Single Topic Conference of The Asian Pacific Journal of Hepatology”. Association for the Study of the Liver (APASL) in 2012, Bangladesh Journal of Hepatology has dedicated its an act that has not been accomplished in most of the presence to compile the specific features of liver countries of Asia with better economical capabilities. diseases in Bangladesh. In addition, it has been acting Now, it is time for ASLDB to assess and act to induce as a bridge to connect knowledge and information qualitative improvement of their inherent heart, Vol. 3 No. 1 05 Bangladesh Journal of Hepatology Bangladesh Journal of Hepatology. Although the quality of generic drugs for HCV infection in a ensuing task is not an easy one, but ASLDB is capable scientifically-amicable manner. This will boost the of taking this challenge to move forward. medical service delivery system of Bangladesh in the At present, the hepatologists have been facing a major context of management of HCV and these approaches challenge about treatment of HCV infection as drugs may reflect the future activities of ASLDB and its journal with potent capacities are now present in market. to move forward with other such medications. However, both aspirations and confusions have been Editors with leadership capabilities, an editorial board of prevailing about these drugs. In Bangladesh, the drugs multidisciplinary specialties and an innovative vision of are cheap and concerns remain if these are efficacious the ASLDB would make it possible to place Bangladesh or not? Bangladesh Journal of Hepatology may devote Liver Journal to its proper position in the field of medical its endeavor to make critical analysis about the journal. effectivity these drugs, especially the content and 06 Vol. 3 No. 1 Bangladesh Journal of Hepatology Original Articles Causes of jaundice in clinical practice: An observation at Brahmanbaria Forhad Hossain Mohammad Shahed1, Mamun Al Mahtab2, Mohammad Fakhrul Islam Khaled1, Mohammad Abul Fayaz1, Ashiqur Rahman Khan1