Acta Scientific Pharmaceutical Sciences (ISSN: 2581-5423) Volume 5 Issue 6 June 2021 Review Article A Comprehensive Review of Flemingia strobilifera (LAM.) Devlekar Shital1*, Khale Anubha2 and Rawal Jignyasha3 Received: April 19, 2021 1Pacific Academy of Higher Education and Research University, Udaipur, India Published: 2Dean, Faculty of Sciences and Technology, SNDT Women’s University, Mumbai, Devlekar Shital., India May 25, 2021 et al. 3Pacific Academy of Higher Education and Research University, Udaipur, India © All rights are reserved by *Corresponding Author: Devlekar Shital, PhD scholar, Pacific Academy of Higher Education and Research University, Udaipur, India. Abstract Flemingia strobilifera Flemingia strobilifera - The traditional systems of medicine plays a significant role in our health care system for the betterment of manhood. - (Lam.) is used as herb in Ayurvedic medicine since ancient time. (Palas) belongs to the family Fa Flemingia strobilifera baceae, grown wildly in many parts of India. The plant is used highly by the countryside and ethnic people in curing various disor of Flemingia strobilifera ders. has an effective natural origin that has a tremendous future for research. The novelty and applicability are hidden. Such things can be removed through modern research. The present article describes various traditional and medicinal utility of the plant and an attempt was made to gather information about the chemical composition of the plantKeywords: or its speciesFlemingia and/or strobilifera its constituents. ; Traditional Uses; Medicinal Uses; Phytochemistry Introduction Morphology Flemingia strobilifera - - - (L.) W.t. Aiton, family Leguminosaea (Fa It is an erect shrub, 5 - 10 ft high, with slight terete branches - baceae) (Figure 1), is also known as ‘Wild Hop’, in Marathi: Kan silky towards their tips. Leaves 3 - 4 inch long, oblong or ovate-lan futi; commonly known as Kusrunt in Hindi; Kanphuti or Bundar ceolate, acute, rounded at the base; lateral nerves 8 - 10 pairs; pe [1]. in Marathi; Nallabaddu, Kannad in Telugu; Kumalu, kumbilteri in tioles half inch; stipules lanceolate, scarious. Racemes terminal, 3 Malayalam; Makhioti in Assam; Simbusak in Bihar - 6 inch long, the slender zigzag rachis rusty-pubescent; bracts 1 - - inch long, shortly stalked, deeply cordate, usually cuspidate at the It grows almost throughout India, Andaman and Nicobar Islan apex. Calyx-teeth lanceolate, pilose, exceeding the tube. Corolla yel ds, ascending to an altitude of 4,500 ft. In Himalayas from Simla . The root of Flemingia strobilifera - - lowish or greenish-white. Pod about half inch, oblong, turgid, finely and Kumaon, mounting to 8000 ft. to Assam, Khasla, Chittagong, - downy, 2-seeded [3] is cylindri Siam, Malacca and Ceylon. Dehradun and Siwalik range, Bundelk cal or slightly tortuous. Root is earthy brownish in color its surface [1]. The hand, from Sind, Rajasthan and Bengal to South India and in Maha was fissured, rootlets and with presence of lenticels. Seeds are two, rashtra region [2] shiny and black. Flowering and fruiting time is Jan to March [4] [5]. flowers recemes, white or pinkish, covered by large folded bracts Ahmad, Hasan and Mahmood reviewed that this is one of the antiurolithic plants from Fabaceae family. Citation: Devlekar Shital., et al. “A Comprehensive Review of Flemingia strobilifera (LAM.)". Acta Scientific Pharmaceutical Sciences 5.6 (2021): 105-110. A Comprehensive Review of Flemingia strobilifera (LAM.) 106 Figure 4: Flemingia strobilifera fresh roots in natural habitat and after drying. Figure 1: Flemingia strobilifera Traditional uses natural habitat. • Flower: Flemingia strobilifera The flower of is traditionally [6]. used as an antitubercular and used to stuff into pillows to • induceLeaves: sleeping The leaves at night of Flemingia in hyperactive strobilifera children [7]. In the Philippines is traditionally used in Java as vermifuge for children a decoction/infusion of the leaves and flowers is prescribed by “curanderose” against tuberculosis [8]. Arabians use it in cosmetics, as anthelmintic and as a remedy for coughs [10] et al. and cold [3,9]. In Malaysia, fever is contained by bathing the patient with a decoction of the leaves . Pizon., reviewed that Subanen Tribe used leaves for treatment to [11]. reduce internal inflammation, Mayoma, cancer and cough Figure 2: Flemingia strobilifera • Stem: - flower in natural habitat. The stem bark is traditionally used to treat inflamma [12]. tory diseases. In Nepals the juice of the bark is given in the • doseRoot: of four teaspoons twice dailyF. strobilifera It is reported that roots of are used by Flemingia strobilifera Santals in epilepsy, insomnia, hysteria and to relieve pain . The Assamese take a small portion of [7-14]. In Burma the roots of are used the root of Flemingia strobilifera to treat epilepsy [8] in order to induce sleep and it is said, in case of severe pain heavy sleep is brought [15] - on according to the amount of root taken, without ill effects - . In India, root paste applied externally to body swell Figure 3: Flemingia strobilifera ings. In Nepal, Root juice (fresh roots crushed in cup of wa [16] et bracts (fresh and dried) in ter) is taken for treating diarrhea and dysentery. In Trinidad al natural habitat. and Tobago, it is used for kidney problems . Pizon., . reviewed that Subanen Tribe used roots for treatment of Citation: Devlekar Shital., et al. “A Comprehensive Review of Flemingia strobilifera (LAM.)". Acta Scientific Pharmaceutical Sciences 5.6 (2021): 105-110. A Comprehensive Review of Flemingia strobilifera (LAM.) 107 [11]. - [27]. - cough, diabetes, cancer and tuberculosis Root decoc tanol and dichloromethane extract of root [34]. Mahato and ract of leaves . • tionTuber: is given in menstrualet al irregularities Chaudhari evaluated antibacterial activity of methanolic ext . • Stems: - Tikdar., . profiles that tuber paste taken orally to [35] cure from dysentery [18] Taqueer and Itankar evaluated anti-inflammatory ac Medicinal uses extracts [19]. tivity of aerial of plant using methanolic and hydro alcoholic [11]. Phytochemistry Medicinal plants certainly have countless importance to human health• Flowers: in the treatment of variety of diseases - - Taqueer and Itankar evaluated anti-inflammatory Gahlot, Lal and Jha studied extracts of ethanolic extracts of root holic extracts [19]. activity of aerial of plant using methanolic and hydro alco for phytochemical screening for presence of total phenolics con • Seeds: tent which possess Antioxidant activity [36]. Nemkul, Bajaracharya - oral contraceptive [20]. and Shrestha studied extracts of Hexane and aqueous methanolic Shreedevi and Patel mentioned the use of seed as an [26] et al. - • Leaves: - extracts of root which shows the presence of polyphenols and ter [21] et al. penoids with Antimicrobial activity . Jeong., evaluated ph Anil, Dora, Gahlot and Tripathi studied anthelmin Fle- Flemingia strobilifera leaves are ytoestrogen for estrogenic effect [37]. Shailajan and Mascarenhas tic activity of methanolic extract of leaves . Madan., mingia tuberosa - [1] evaluated Kaempferol from ethanolic extracts of aerial parts mentioned that decoction of ferol et al in vitro - with roots showing maximum content of Kaemp used as a health tonic by rubbing it on the body . Pizon., [22] et al. [38]. Madan, Gullaiya, Singh and Kumar performed review of . studied antioxidant activity of 80% hydromet - previous chemical studies which showed that flavonoids, flavonoid hanolic and aqueous extract of leaves . Quevedo., [1] - rol level et al. glycosides, chalcones, epoxychromenes and pterocarpans are main studied effect of ethanolic extract of leaf on blood choleste constituents found in Strobilifera species . Pizon, Nuneza, Myle [23]. Anil Kumar., studied Hepatoprotective ne and Senarath studies aqueous and hydromethanolic extracts of of the leaves [22] effect of Chloroform extract of leaf on paracetamol induced leaf for total phenolics content and studied Antioxidant property hepatotoxicity [24]. Ramachandran, Clement and Maxwell of leaves [25] - . Hua, Zhai, and Zhongdong performed review on studied cytotoxic effect of petroleum and chloroform extract different classes of compounds present in genus Flemingia Roxb . Taqueer and Itankar evaluated anti-inflamma alcoholic extracts [19]. which states the presence of main groups: flavones, triterpenes tory activity of aerial of plant using methanolic and hydro accompanied with sterols and anthraquinones [39]. Pizon antin, • Roots in vitro extract of leaf of Flemingia strobilifera Nuneza, Uy and Senaratha studied aqueous and 80% methanolic - : Nemkul, Bajracharya and Shrestha reported for determination of total [26] - antimicrobial activity of roots using Hexane and 70% Met phenolic content; where aqueous extract shows high phenolic [22]. Ma- hanol extract using GC-MS technique . Soe, Thein and Oo content in comparison of hydromethanolic extract; however, hyd extract [27] - evaluated wound healing property using 70% ethanolic root romethanolic extract exhibited high antioxidant activity . Thakur., et al. Flemingia strobilifera . Kavita G, Vijay KL, Shivesh J studied anticon hajon B, Remadevi R, Sunil Kumar KN, Ravishankar B performed [29]. Anil vulsant activity of ethanol extract of root [28] preliminary analysis of root of which showed studied anxiolytic effect of aqueous extract of root presence of carbohydrate, cumarins, flavonoids, phenols, quinine, extract of root . Chen., et al - kumar KV studied anti ulcerogenic property