Organization in Special Consultative Status with the UN Economic and Social Council www.allianceforum.org/en 2015 World Alliance Forum in San Francisco Regenerative Medicine: Let’s Talk Business! Golden Gate Club November 12 - 13, 2015 Organized by: Alliance Forum Foundation Government of Japan www.wafsf.org Table of Contents Page Greetings 3 Program 6 Speakers’ Biography 10 Sponsors & Major Supporting Organizations 27 Alliance Forum Foundation 37 2 Greetings Organization in Special Consultative Status with the UN Economic and Social Council Greetings from George Hara Chairman of the Board, Alliance Forum Foundation The Alliance Forum Foundation began holding its annual World Alliance Forum in the 1990s with a goal to nurture emerging technologies in the fields of IT and healthcare. Since then, the Forum has continued to be a catalyst for many new alliances among businesses, research institutions, governments, and local and international organizations that enable commercialization of innovative technologies. Since 2013, the Foundation has been inviting leading researchers engaged in stem cell research and development in Japan and the US to come together in San Francisco. Dr. Shinya Yamanaka, a 2012 Nobel Prize laureate in Physiology or Medicine and who discovered induced pluripotent stem cells (iPSC), has accelerated the development and translation of regenerative medicine. It became clear that this revolutionary technology would not only change our healthcare system but also impact our society in the most fundamental way. At this year's Forum “Regenerative Medicine: Let’s Talk Business!,” I look forward to seeing top researchers and business leaders from the US, Japan and other parts of the world come together to discuss current developments in clinical applications and business opportunities in regenerative medicine and share information which is vital to building social consensus towards regenerative medicine and coming Life Science Revolution. We will also hear about exciting opportunities for investors and businesses in this burgeoning field. It is my hope that as new and existing businesses achieve success, a portion of the profits will be directed back to funding further research in the spirit of public interest capitalism so that the stem cell technology may continue to make huge strides toward becoming a new engine of industrial growth for the benefit of all. I thank all the presenters who are coming together to make the 2015 World Alliance Forum in San Francisco “Regenerative Medicine: Let’s Talk Business!” a valuable and important program of shared expertise and dialogue. I also want to recognize the generosity of our sponsors who made this year's Forum possible. Ambassador George Hara Chairman of the Board, Alliance Forum Foundation Organization in Special Consultative Status with the UN ECOSOC Special Advisor to the Cabinet Office of the Prime Minister of Japan 3 Greetings from Jun Yamada Consul General of Japan in San Francisco Facing a rapidly aging population, the Government of Japan places serious focus on the field of health and science. The United States will eventually enter into the same situation. There is no doubt that our two countries need to cooperate in the closest manner to overcome this structural problem in our common future. Earlier this year, Prime Minister Abe visited San Francisco and the Bay Area. It was the first such visit in 26 years and turned out to be so productive. During his stay, PM Abe managed to visit many academic and research facilities. At the Gladstone Institutes, he made a speech and held private meetings with its leadership. He addressed a gathering of 100 young Japanese researchers from the University of California and at Stanford University he announced the “Innovation Kakehashi Project”. One of its components is to facilitate collaboration through its Biodesign program. It is my hope that such initiatives will further enhance the bridge between our two countries across the Pacific. The steadfast mission of the World Alliance Forum, “to identify cutting-edge technologies, encourage sustainable social and industrial development founded on those technologies, and promote social change for the advancement of our society”, is exactly in line with this most encouraging recent development. Please accept my heartfelt congratulations on the opening of the 2015 World Alliance Forum in San Francisco. I sincerely look forward to enlightening myself on the newest US-Japan collaborations in the field of regenerative medicine through this wonderful forum. Consul General Jun Yamada Consul General of Japan in San Francisco 4 Event Summary 2015 World Alliance Forum in San Francisco Theme: Regenerative Medicine: Let’s Talk Business! Date & Time: Thursday November 12th, 2015 9:00 am – 5:30 pm (Reception: 5:30 pm – 6:30 pm) Friday November 13th, 2015 9:00 am – 4:30 pm (Reception: 4:30 pm – 5:30 pm) Location: Golden Gate Club (135 Fisher Loop, San Francisco, CA 94129) Organizers: Alliance Forum Foundation (Organization in Special Consultative Status with the UN ECOSOC) Government of Japan Platinum Astellas Pharma Inc. DEFTA PARTNERS Sponsors: Mitsui Fudosan Co., Ltd. MUFG Union Bank, N.A. ROHTO Pharmaceutical Co., Ltd. Takeda Pharmaceutical Company Ltd. Gold California Institute for Regenerative Medicine (CIRM) Chugai Pharmaceutical CO., LTD. Sponsors: Fujifilm Corporation / Cellular Dynamics International Lonza Mitsubishi Tanabe Pharma Corporation Silver Sponsors: Terumo Corporation Yorozu Law Group Bronze Sponsor: Cesca Therapeutics SanBio, Inc. Wi-Fi Sponsor: Lonza In-Kind AlphaGraphics ITO EN (North America) Inc. Sponsors: JFC International, Inc. KOBE SHU-SHIN-KAN BREWERIES, LTD. SAPPORO U.S.A., Inc. Ms. Tomoko Tsuji (IKENOBO Flower Arrangement) Major Alliance for Regenerative Medicine (ARM) BioCentury Supporting Center for iPS Cell Research and Application (CiRA), Forum for Innovative Regenerative Medicine (FIRM) Organizations: Kyoto University Gladstone Institutes Hara Research Foundation (HRF) International Society for Stem Cell Research (ISSCR) The Japanese Society for Regenerative Medicine (JSRM) Supporting Alliance Forum Executive Club Japan Bio Community (JBC) Organizations: Japan Society of Northern California Japanese Chamber of Commerce of Northern California Japanese University Network of the Bay Area (JUNBA) (JCCNC) JETRO (Japan External Trade Organization) Keizai Society Student Society for Stem Cell Research (SSSCR) US-Asia Technology Management Center at Stanford University Advisory Dr. Chihiro Akazawa, Vice Dean & Professor, Department of Biochemistry and Biophysics, Graduate School of Board: Health Care Sciences, Tokyo Medical Dental University Dr. Ken-ichi Arai, Professor Emeritus and former Dean, the Institute of Medical Science, The University of Tokyo (IMSUT), Founder & Chairman, SBI Biotech, Co., Ltd. Dr. Robert Mahley, Founder & President Emeritus, Gladstone Institutes Dr. Henry A. McKinnell, Jr., former Chairman and CEO of Pfizer, Inc. Dr. Hiromitsu Nakauchi, Professor, Stanford University and The University of Tokyo Dr. Hideyuki Okano, Dean, Keio University School of Medicine; Professor, Department of Physiology, Keio Univer- sity School of Medicine Dr. Yoshiki Sawa, Dean & Professor, Graduate School of Medicine, Osaka University Dr. Deepak Srivastava, Director, Gladstone Institutes Dr. Irving Weissman, Director, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Dr. Shinya Yamanaka, Director & Professor, Center for iPS Cell Research and Application, Kyoto University 5 Program: Thursday, November 12, 2015 <Day 1> Thursday, November 12, 2015 09:00-09:05 MC: Ms. Yoriko Kishimoto, Former Mayor, City of Palo Alto 09:05-09:10 Opening Remark Mr. Isao “Steve” Matsuura, Council Member, Alliance Forum Foundation 09:10-09:15 Welcome Remark The Hon. Jun Yamada, Consul General of Japan, Consulate General of Japan in San Francisco 09:15-09:20 Guest Remark Dr. Jonathan Thomas, Chair, Governing Board of the California Institute for Regenerative Medicine (CIRM) (Independent Citizens Oversight Committee) Session I: Regenerative Medicine Industry Update 09:20-09:30 2015 Regenerative Medicine Research Update Ms. Susan Solomon, Co-Founder & CEO, The New York Stem Cell Foundation 09:30-09:40 2015 Regenerative Medicine Industry Update (USA) Mr. Michael Werner, Executive Director, Alliance for Regenerative Medicine 09:40-09:50 2015 Regenerative Medicine Industry Update (Japan) Mr. Yuzo Toda, Representative Director & Chairman, Forum for Innovative Regenerative Medicine 09:50-10:20 Panel Discussion: 2015 Regenerative Medicine Industry Update Moderator: Dr. Jonathan Thomas, Chair, Governing Board of the CIRM (Independent Citizens Oversight Committee) Ms. Susan Solomon, Chief Executive Officer, The New York Stem Cell Foundation Mr. Yuzo Toda, Representative Director, Forum for Innovative Regenerative Medicine Mr. Michael Werner, Executive Director, Alliance for Regenerative Medicine 10:20-10:40 Coffee Break 10:40-10:45 Guest Remark Mr. Kan Suzuki, Advisor, Ministry of Education, Culture, Sports, Science and Technology 10:45-10:55 Company Presentation 1: ROHTO Pharmaceutical Co., Ltd. Dr. Katsuya Hisamichi, Executive Officer, Rohto Pharmaceutical Co., Ltd. Session II: Road to Commercialization (Part 1) 10:55-11:00 Moderator: Ms. Susan Solomon, Co-Founder & CEO, The New York Stem Cell Foundation 11:00-11:25 <Case I: SanBio, Inc.> Dr. Hideyuki Okano, Dean, Keio University School of Medicine, Professor, Department of Physiolo- gy, Keio University School of Medicine