Known Bioactive Library: Microsource 1 - US Drug Collection ICCB-L ICCB-L Vendor Vendor Compound Name Bioactivity Source CAS Plate Well ID antifungal, inhibits Penicillium 2091 A03 Microsource 00200046 GRISEOFULVIN 126-07-8 mitosis in metaphase griseofulvum 3505-38-2, 486-16-8 2091 A04 Microsource 01500161 CARBINOXAMINE MALEATE antihistaminic synthetic [carbinoxamine] 2091 A05 Microsource 00200331 SALSALATE analgesic synthetic 552-94-3 muscle relaxant 2091 A06 Microsource 01500162 CARISOPRODOL synthetic 78-44-4 (skeletal) antineoplastic, 2091 A07 Microsource 00210369 GALLIC ACID insect galls 149-91-7 astringent, antibacterial 66592-87-8, 50370-12- 2091 A08 Microsource 01500163 CEFADROXIL antibacterial semisynthetic 2 [anhydrous], 119922- 89-9 [hemihydrate] Rheum palmatum, 2091 A09 Microsource 00211468 DANTHRON cathartic 117-10-2 Xyris semifuscata 27164-46-1, 25953-19- 2091 A10 Microsource 01500164 CEFAZOLIN SODIUM antibacterial semisynthetic 9 [cefazolin] glucocorticoid, 2091 A11 Microsource 00300024 HYDROCORTISONE adrenal glands 50-23-7 antiinflammatory 64485-93-4, 63527-52- 2091 A12 Microsource 01500165 CEFOTAXIME SODIUM antibacterial semisynthetic 6 [cefotaxime] 2091 A13 Microsource 00300029 DESOXYCORTICOSTERONE ACETATE mineralocorticoid adrenocortex 56-47-3 58-71-9, 153-61-7 2091 A14 Microsource 01500166 CEPHALOTHIN SODIUM antibacterial semisynthetic [cephalothin] 2091 A15 Microsource 00300034 TESTOSTERONE PROPIONATE androgen, antineoplastic semisynthetic 57-85-2 24356-60-3, 21593-23- 2091 A16 Microsource 01500167 CEPHAPIRIN SODIUM antibacterial semisynthetic 7 [cephapirin] 6160-12-9, 299-39-8 Lupinus spp and 2091 A17 Microsource 00300548 SPARTEINE SULFATE oxytocic [anhydrous], 90-39-1 other Leguminosae [sparteine] 38821-53-3 [anhydrous], 58456-86- 2091 A18 Microsource 01500168 CEPHRADINE antibacterial semisynthetic 3 [dihydrate], 31828- 50-9 [non- stoichiometric hydrate] Ruta graveolens, 2091 A19 Microsource 00300607 RUTOSIDE (rutin) vascular protectant 153-18-4 widespread in plants 6004-24-6, 123-03-5 2091 A20 Microsource 01500169 CETYLPYRIDINIUM CHLORIDE antiinfective (topical) synthetic [anhydrous] 2091 A21 Microsource 00300618 SALICYLANILIDE antipyretic, fungicide synthetic 87-17-2 antineoplastic, alkylating 2091 A22 Microsource 01500171 CHLORAMBUCIL synthetic 305-03-3 agent cardiotonic, 62-31-7, 51-61-6 2091 B03 Microsource 01500263 DOPAMINE HYDROCHLORIDE synthetic antihypotensive [dopamine] antineoplastic, alkylating 55-86-7, 51-75-2 2091 B04 Microsource 01500375 MECHLORETHAMINE synthetic agent [mechlorethamine] 1229-29-4, 1668-19-5 [doxepin], 4698-39-9 2091 B05 Microsource 01500264 DOXEPIN HYDROCHLORIDE antidepressant synthetic [(//E//)-isomer], 25127- 31-5 [(//Z//)-isomer] 31884-77-2, 1104-22- 2091 B06 Microsource 01500376 MECLIZINE HYDROCHLORIDE antiemetic synthetic 9 [anhydrous], 569-65- 3 [meclizine] semisynthetic; GS- 17086-28-1, 564-25-0 2091 B07 Microsource 01500266 DOXYCYCLINE HYDROCHLORIDE antibacterial 3065 [anhydrous] antiinflammatory, 2091 B08 Microsource 01500377 MECLOFENAMATE SODIUM synthetic 6385-02-0 antipyretic 562-10-7, 469-21-6 2091 B09 Microsource 01500267 DOXYLAMINE SUCCINATE antihistaminic, hypnotic synthetic [doxylamine] 71-58-9, 520-85-4 2091 B10 Microsource 01500379 MEDROXYPROGESTERONE ACETATE contraceptive semisynthetic [medroxyprogesterone ] 536-43-6, 586-60-7 2091 B11 Microsource 01500268 DYCLONINE HYDROCHLORIDE anesthetic (topical) synthetic [dyclonine] 2091 B12 Microsource 01500380 MEDRYSONE glucocorticoid semisynthetic 2668-66-8 PDE inhibitor, 2091 B13 Microsource 01500269 DYPHYLLINE bronchodilator, synthetic 479-18-5 vasodilator progestogen, 595-33-5, 3562-63-8 2091 B14 Microsource 01500381 MEGESTROL ACETATE semisynthetic antineoplastic [megestrol] TRISODIUM ETHYLENEDIAMINE chelating agent, 2091 B15 Microsource 01500270 synthetic 150-38-9 TETRACETATE antioxidant antineoplastic, alkylating 2091 B16 Microsource 01500382 MELPHALAN synthetic 148-82-3 agent Microsource1-US Drug Collection Page 1 of 24 Created 9/2015 ICCB-L ICCB-L Vendor Vendor Compound Name Bioactivity Source CAS Plate Well ID inhibits RNA, DNA and Uragoga 316-42-7, 483-18-1 2091 B17 Microsource 01500272 EMETINE protein synthesis ipecacuanha [emetine] 76-90-4, 25990-43-6 2091 B18 Microsource 01500383 MEPENZOLATE BROMIDE anticholinergic synthetic [mepenzolate] antirachitic vitamin; LD50 irradiation of 2091 B19 Microsource 01500276 ERGOCALCIFEROL 50-14-6 (rat) 56 mg/kg po ergosterol antineoplastic, purine 6112-76-1, 50-44-2 2091 B20 Microsource 01500387 MERCAPTOPURINE synthetic antimetabolite [anhydrous] ergot and 129-51-1, 60-79-7 2091 B21 Microsource 01500277 ERGONOVINE MALEATE oxytocic, 5HT antagonist Convolvulvaceae [ergonovine] spp estrogen, with 2091 B22 Microsource 01500388 MESTRANOL progesterone as oral semisynthetic 72-33-3 contraceptive antibacterial synthetic; NSC- 2091 C03 Microsource 00305025 PHENYL AMINOSALICYLATE 133-11-9 (tuberculostatic) 40144 antibacterial, 2091 C04 Microsource 01500172 CHLORAMPHENICOL PALMITATE semisynthetic 530-43-8 antirickettsial mamallian male 2091 C05 Microsource 00307023 TESTOSTERONE androgen, antineoplastic 58-22-0 hormone antibacterial, 982-57-0, 56-75-7 2091 C06 Microsource 01500173 CHLORAMPHENICOL HEMISUCCINATE antirickettsial, inhibits semisynthetic [chloramphenicol] protein synthesis derivative of cardiotonic, uterine 4884-68-8, 6592-85-4 2091 C07 Microsource 00310006 HYDRASTININE HYDROCHLORIDE hydrastine hemostatic [hydrastinine] (01501009) antibacterial, Streptomyces 2091 C08 Microsource 01500174 CHLORAMPHENICOL antirickettsial, inhibits 56-75-7 venezuelae protein synthesis antineoplastic, antiplaque Sanguinaria 2091 C09 Microsource 00310035 SANGUINARINE SULFATE 5578-73-4 agent canadensis 1620-21-9, 82-93-9 2091 C10 Microsource 01500175 CHLORCYCLIZINE HYDROCHLORIDE H1-antihistamine synthetic [base] soya, wheat germ 2091 C11 Microsource 00310039 alpha-TOCHOPHEROL vitamin E 59-02-9 and other plant oils antibacterial (topical), 3697-42-5, 55-56-1 2091 C12 Microsource 01500177 CHLORHEXIDINE synthetic disinfectant [chlorhexidine] 2091 C13 Microsource 00310040 alpha-TOCHOPHERYL ACETATE vitamin E derivative 58-95-7 2091 C14 Microsource 01500178 CHLOROCRESOL antiinfectant synthetic 59-50-7 2091 C15 Microsource 00310050 QUININE ETHYL CARBONATE antimalarial semisynthetic 83-75-0 antimalarial, antiamebic, 2091 C16 Microsource 01500179 CHLOROQUINE DIPHOSPHATE antirheumatic, synthetic 54-05-7 intercalating agent antineoplastic, 2091 C17 Microsource 00330001 DACTINOMYCIN Actinomyces spp 50-76-0 intercalating agent 2091 C18 Microsource 01500180 CHLOROTHIAZIDE diuretic, antihypertensive synthetic 58-94-6 Streptomyces 2091 C19 Microsource 00330002 MITOMYCIN C antineoplastic 50-07-7 verticillatus 2091 C20 Microsource 01500181 CHLOROTRIANISENE estrogen synthetic 569-57-3 insecticide, 2091 C21 Microsource 00330018 DICHLORVOS synthetic 62-73-7 cholinesterase inhibitor antibacterial, topical and 2091 C22 Microsource 01500182 CHLOROXYLENOL synthetic 88-04-0 urinary antiseptic 1264-62-6, 114-07-8 2091 D03 Microsource 01500279 ERYTHROMYCIN ETHYLSUCCINATE antibacterial semisynthetic [erythromycin] 586-06-1, 5874-97-5 2091 D04 Microsource 01500390 METAPROTERENOL bronchodilator synthetic [metaproterenol sulfate] Streptomyces 2091 D05 Microsource 01500280 ERYTHROMYCIN antibacterial 114-07-8 erythreus cholinergic, diagnostic 62-51-1, 55-92-5 2091 D06 Microsource 01500391 METHACHOLINE CHLORIDE synthetic aid [methacholine] 2091 D07 Microsource 01500282 ESTRADIOL estrogen pregnancy urine 50-28-2 2091 D08 Microsource 01500394 METHENAMINE antibacterial (urinary) synthetic 100-97-0 2091 D09 Microsource 01500283 ESTRADIOL CYPIONATE estrogen semisynthetic 313-06-4 7246-14-2, 132-92-3 2091 D10 Microsource 01500395 METHICILLIN SODIUM antibacterial semisynthetic [anhydrous], 61-32-5 [methicillin] 2091 D11 Microsource 01500284 ESTRADIOL VALERATE estrogen semisynthetic 979-32-8 2091 D12 Microsource 01500396 METHIMAZOLE antihyperthyroid synthetic 60-56-0 mammalian 50-27-1, 514-68-1 [as, 2091 D13 Microsource 01500285 ESTRIOL estrogen hormone succinate] muscle relaxant 2091 D14 Microsource 01500397 METHOCARBAMOL synthetic 532-03-6 (skeletal) Microsource1-US Drug Collection Page 2 of 24 Created 9/2015 ICCB-L ICCB-L Vendor Vendor Compound Name Bioactivity Source CAS Plate Well ID pregnacy urine, 2091 D15 Microsource 01500286 ESTRONE estrogen dates and Punica 53-16-7 granatum seeds antineoplastic, synthetic; 2091 D16 Microsource 01500398 METHOTREXATE(+/-) antirheumatic, folic acid 60388-53-6 AMETHOPTERIN antagonist 2091 D17 Microsource 01500287 ETHACRYNIC ACID diuretic synthetic 58-54-8 alpha1 adrenoreceptor 61-16-5, 390-28-3 2091 D18 Microsource 01500399 METHOXAMINE HYDROCHLORIDE synthetic agonist, vasoconstrictor [methoxamine] antibacterial 1070-11-7, 74-55-5 2091 D19 Microsource 01500288 ETHAMBUTOL HYDROCHLORIDE synthetic (tuberculostatic) [ethambutol] antipsoriatic, 2091 D20 Microsource 01500400 METHOXSALEN amni visnaga 298-81-7 pigmentation agent estrogen, plus 2091 D21 Microsource 01500291 ETHINYL ESTRADIOL progestogen as oral semisynthetic 57-63-6 contraceptive 2091 D22 Microsource 01500401 METHSCOPOLAMINE BROMIDE anticholinergic semisynthetic 155-41-9 2091 E03 Microsource 00330062 TEMEFOS insecticide synthetic 3383-96-8 113-92-8, 132-22-9 2091 E04 Microsource 01500183 CHLORPHENIRAMINE (S) MALEATE antihistaminic synthetic [chlorpheniramine] synthetic; gamma- 2091 E05 Microsource 00330071 LINDANE insecticide 58-89-9 BHC 2091 E06 Microsource 01500184 CHLORPROMAZINE antiemetic, antipsychotic synthetic 50-53-3