Environmental Health & Safety Oklahoma State University Laboratory Safety Manual January 2016 Contents 1. Approvals and Revisions ........................................................................................................................................... 1 2. Preface .............................................................................................................................................................................. 3 3. General Program Requirements ............................................................................................................................ 5 3.1 Roles and Responsibilities ............................................................................................................................. 5 3.2 Training ................................................................................................................................................................. 6 3.3 Visitors/Minors in Lab .................................................................................................................................... 7 3.4 Working Alone Policy ...................................................................................................................................... 8 3.5 Basic Rules ........................................................................................................................................................... 8 3.6 Emergency Response ..................................................................................................................................... 10 3.7 Contact Information ....................................................................................................................................... 11 4. Laboratory Design and Safety Features ............................................................................................................ 12 4.1 Ventilation .......................................................................................................................................................... 12 4.2 Fire & Life Safety.............................................................................................................................................. 15 4.3 Emergency Safety Equipment .................................................................................................................... 15 4.4 Signage................................................................................................................................................................. 16 5. General Lab Practices ............................................................................................................................................... 17 5.1 Housekeeping ................................................................................................................................................... 17 5.2 Personal Protective Equipment (PPE) .................................................................................................... 17 5.3 Safety Data Sheet ............................................................................................................................................. 18 5.4 Glassware ........................................................................................................................................................... 18 5.5 Unattended Experiments ............................................................................................................................. 19 5.6 Spill Policy .......................................................................................................................................................... 19 5.7 Laboratory Decommissioning .................................................................................................................... 20 6. Chemical Managements ........................................................................................................................................... 21 6.1 Chemical Procurement and Storage ......................................................................................................... 21 6.2 General Handling and Transporting Chemicals................................................................................... 23 6.3 Chemical Inventory ........................................................................................................................................ 24 6.4 Chemical Labeling ........................................................................................................................................... 24 6.5 Incompatibles ................................................................................................................................................... 25 6.6 Chemical Disposal ........................................................................................................................................... 25 6.7 Inspections ......................................................................................................................................................... 28 7. Procedures for Common Categories of Hazardous Chemicals ................................................................. 29 7.1 Flammable Liquids ......................................................................................................................................... 29 7.2 Oxidizers ............................................................................................................................................................. 30 7.3 Corrosives (Acid and Bases) ....................................................................................................................... 32 7.4 Reactives ............................................................................................................................................................. 34 7.5 Compressed Gas ............................................................................................................................................... 37 7.6 Nanomaterials (Initial Guidance) .............................................................................................................. 39 7.7 Cryogenic Materials ........................................................................................................................................ 41 8. Particularly Hazardous Chemicals and Other Less Common Hazards .................................................. 43 8.1 Particularly Hazardous Chemical Precautions .................................................................................... 43 8.2 Chemical of High Chronic and Acute Toxicity ...................................................................................... 44 8.3 Carcinogens ....................................................................................................................................................... 44 8.4 Teratogens, Mutagens, and Embryotoxins ............................................................................................ 45 8.5 Allergen and Sensitivities ............................................................................................................................. 45 8.6 Epoxy Resin Components ............................................................................................................................. 45 8.7 New Compounds (Compounds without SDS) ....................................................................................... 46 8.8 Biological, LASER and Radiation Safety .................................................................................................. 46 9. Medical ........................................................................................................................................................................... 47 9.1 Employee Exposure ........................................................................................................................................ 47 9.2 Monitoring ......................................................................................................................................................... 48 10. Department Documentation .................................................................................................................................. 49 10.1 Department Laboratory Safety Manual .................................................................................................. 49 10.2 Standard Operating Procedures ................................................................................................................ 49 10.3 Incident and Near Miss Reports ................................................................................................................ 50 10.4 Documentation Control................................................................................................................................. 50 11. Department Specific Procedures ......................................................................................................................... 51 12. Index ............................................................................................................................................................................... 53 Appendix 1: Terms and Definitions ........................................................................................................................... 55 Appendix 2: References .................................................................................................................................................