advancing innovation + discovery Duke Health Named Professorships DUKE HEALTH to establish endowed scientific opportunities professorships are gifts here and around the world. Endowed professorships that last forever. Once Great universities succeed are the highest academic inaugurated, they continue on the strength of the honor that the Duke in perpetuity, passing in partnerships they form University School of time from one exceptional with their supporters and Medicine or School of faculty member to the benefactors. Everyone who Nursing can bestow upon a next. Every endowed establishes an endowed faculty member. professorship is both a professorship at Duke These prestigious profound honor for the Health joins with us in positions honor our most faculty member who holds our mission to deliver accomplished physician- it and a meaningful legacy tomorrow’s health care and nurse-scientists and to the visionary benefactor today, accelerate research clinicians. They celebrate who establishes it. and its translation, and Duke University those who demonstrate That legacy is evident in the create education that A. Eugene Washington, extraordinary achievement pages that follow, as we is transforming. We are School of Medicine in advancing scholarship, MD, MSc profile our philanthropic deeply grateful for these Introduction Chancellor for Health Affairs, science, and human Dean Mary E. Klotman, MD 5 Duke University partners who have partners, who, as you health. And perhaps most President and CEO, generously invested in will read, have propelled importantly, they nurture Duke University Health System endowed professorships our professors and our Nobel Prize Recipients 6 innovation, discovery, at Duke Health. They institution to even greater and the expansion of the have demonstrated heights of excellence and Donors & Professors 8 boundaries of knowledge. their commitment by impact. As we seek to shape empowering our acclaimed We are truly Advancing the future of health faculty, our sharpest Health Together. and health care at Duke minds, and most visionary Sincerely, Health, we are making researchers and educators endowed professorships to take on the most a foundational priority. pressing health challenges Philanthropic efforts and pursue promising advancing innovation + discovery Duke University Duke University Lists and Indices Emeriti Professors School of Medicine School of Nursing Introduction Introduction Professorships to be Appointed 106 Dean Mary E. Klotman, MD 5 Dean Marion E. Broome, PhD, RN, FAAN 101 Named Professorships Not Fully Funded Index of Named Professorships Nobel Prize Recipients 6 Professors 102 107 Index of Faculty Who Hold Donors & Professors 8 Endowed Professorships 109 Index of Featured Donors 110 advancing innovation + discovery DUKE UNIVERSITY educators and mentors reaching philanthropic SCHOOL OF MEDICINE who guide our students investments one can make. and trainees. We are profoundly grateful Because of our outstanding At Duke, we aim to be the to the many donors who faculty, Duke University destination of choice for have joined with us to School of Medicine is the nation’s most talented advance the bounds of alive with innovation and leaders and promising knowledge. progress, a place where young faculty in biomedical advances in research and sciences. Endowed patient care are made, professorships are perhaps and health care leaders of the most valuable tool today teach and train those for the recruitment and of tomorrow. retention of these high As evidenced by the faculty caliber individuals. profiled in this book, Duke Mary E. Klotman, MD As you see in the faculty DUKE UNIVERSITY SCHOOL OF MEDICINE is home to individuals Dean, Duke University School profiled here, endowed recognized for their efforts of Medicine Vice Chancellor for Health Affairs, professorships provide to transform medicine and Duke University the brightest minds with 5 health through pioneering the dedicated support scientific research needed to achieve and the translation of boundary-pushing science, breakthrough discoveries care for our patients to the most advanced care and the community, and for patients. It is home educate and train the next to the most skilled and generation of leaders. compassionate physicians and to passionate Endowed professorships are among the most far- DUKE HEALTH NAMED PROFESSORSHIPS Robert J. Lefkowitz, MD, was signals to a G protein inside it, See page 39 for Lefkowitz’s on track to spend his career as allowing the cell to respond professional profile. a clinical physician when the appropriately. Because this call of the laboratory became process is involved in numerous too insistent to resist. After diseases, G protein-coupled his first six months as a senior receptors are a target for more resident at Massachusetts than a third of all modern General Hospital, he broke pharmaceutical drugs. from the customary path and In addition to his research, returned to research, which he Lefkowitz is renowned as had gotten a taste for during a mentor. More than 200 two years at the National graduate students and post- Institutes of Health. While he docs—including Brian Kobilka, has spent the majority of his now at Stanford, with whom 45-year professional career in he shared the Nobel Prize— DUKE UNIVERSITY SCHOOL OF MEDICINE the lab at Duke, he continued have learned under Lefkowitz’s to make clinical teaching tutelage. And they still do, as Robert J. 6 rounds for decades and still he continues to explore the , MD holds an active medical license. secrets of receptors because, as Lefkowitz James B. Duke Professor of Medicine His research on cell surface he once said, in science “there’s receptors earned him the 2012 always a new detail to discover. Awarded the 2012 Nobel Prize for Chemistry Nobel Prize in Chemistry, the It’s like peeling an onion.” first ever awarded to a Duke faculty member. Lefkowitz won the Nobel Prize for his seminal discoveries on G protein-coupled receptors, DUKE HEALTH NAMED PROFESSORSHIPS which detect a huge variety of stimuli outside the cell membrane and transmit Nobel Laureates See page 34 for Modrich’s When Paul L. Modrich, PhD, as chromosomes replicate. professional profile. was growing up in New Errors in the genetic code Mexico, his father, a local frequently transpire during high school biology teacher, replication within the body’s 10 told him, “You should learn trillion cells. These errors about this DNA stuff, because are recognized and corrected it’s really interesting.” Rarely by mismatch repair (MMR), has a father’s advice been so and Modrich showed how thoroughly embraced: Modrich this works. has spent his entire career His basic science research studying “this DNA stuff,” and turned out to have significant he’s done it so exceptionally implications for human health, that in 2015 he was one of as Modrich and others showed three researchers to share the that defects in the MMR Nobel Prize in Chemistry. system are the cause of one DUKE UNIVERSITY SCHOOL OF MEDICINE Modrich came to Duke in of the most common forms of Robert J. Paul L. 1976 from the University of hereditary cancer and play a , MD , PhD California at Berkeley and says central role in the development 7 Lefkowitz Modrich he felt at home right away of certain sporadic tumors as James B. Duke Professor of Medicine James B. Duke Professor of Biochemistry in a small department with well. “Science moves in little Awarded the 2015 Nobel Prize for Chemistry Awarded the 2012 Nobel Prize for Chemistry an exceptional and collegial steps,” Modrich says, “and you faculty. He carried on his don’t always know where you’ll research and won the Nobel end up when you set out.” Prize for some four decades of investigation into how cells repair errors that occur in DNA DUKE HEALTH NAMED PROFESSORSHIPS GIVEN BY DUKE UNIVERSITY GIVEN BY DUKE UNIVERSITY Duke University established this professorship Duke University established this professorship in 2005 to support a faculty member in the in 2005 to support a faculty member in the Department of Anesthesiology. Department of Anesthesiology. Distinguished RU-RONG JI, PHD Distinguished DAVID S. WARNER, MD Professor of Distinguished Professor of Anesthesiology Professor of Distinguished Professor of Anesthesiology Anesthesiology Additional Appointments and Affiliations Anesthesiology Additional Appointments and Affiliations • Professor of Anesthesiology • Professor of Anesthesiology • Professor in Neurobiology • Professor in Neurobiology • Professor of Surgery Education and Training • Faculty Network Member, Duke Institute for Brain Sciences • Postdoctoral Fellow, Peking University • Vice Chair, Research, Department of Anesthesiology • Postdoctoral Fellow, Karolinska Institute • Chief, Division of Basic Sciences, Department of • Postdoctoral Fellow, Johns Hopkins School of Medicine Anesthesiology • PhD, Chinese Academy of Sciences Education and Training Selected Awards and Honors • MD, University of Wisconsin–Madison • Outstanding Research Award, Nature Publishing Group SciCafé Selected Awards and Honors DUKE UNIVERSITY SCHOOL OF MEDICINE • Transformative Research Award, National Institutes • Award for Translational Research Mentoring, Duke University of Heath (NIH) School of Medicine • Basis Research Advances Award, NIH • Award for Mentoring Excellence in Research, Foundation for 8 • Plenary lecture speaker, 14th World Congress on Anesthesia Education and Research, American Society of Pain, Milan, Italy Anesthesiologists Ru-Rong Ji • Speaker, NIH Pain Consortium David S. Warner • Distinguished