CONFERENCE TIME TABLE 6 April 7-8, 2019, Hilton Tel Aviv Hotel The 48th Annual Meeting of the Israel Endocrine Society PROGRAM AT A GLANCE Sunday, April 7, 2019 15:30-15:50 Coffee Break 07:30-08:30 Registration and Gathering 15:50-16:50 Meet the Expert Hall A Meet the Expert Hall B Novel Avenues in the Management of Endocrine Hypertension 08:30-10:00 Parallel Oral Presentations Congenital Adrenal Hyperplasia Felix Beuschlein Thyroid Reproduction Obesity, Metabolic Syndrome Nils P Krone University Hospital of Zurich Chairs: Dania Hirsch, Chairs: Talia Geva Eldar, Chairs: Yonit Marcus- Perlman, Sheffield, UK Carlos Benbassat Joseph Orly Rosane Abramof-Ness 16:50-17:30 IES Members General Assembly Hall A Hall A Hall B Hall C Executive Committee Report 10:00-10:20 Coffee Break Accountant Report 10:20-11:20 Poster Session Poster Hall Prize lectures Hall A 11:20-12:10 Chair: Avraham Karasik Lindner Prize, Eyal Robenshtok Chowers Prize, Yael Riahi Outstanding Community Physician Award, Elizabeta Baron Plenary lecture 1 Hall A Fat in the Blood, Fat in the Heart 12:10-13:00 Ira Goldberg, NYU School of Medicine, NYU Langone Health Chair: Hannah Kanety 13:00-14:00 Lunch 14:00-15:30 Parallel Symposia Symposium 1 Hall A Symposium 2 Hall B Congenital Adrenal Hyperplasia (CAH) Big Data – Digital Health in in 2019 Endocrinology Chairs: Naomi Weintrob, David Zangen Chairs: Moshe Phillip, Irit Hochberg 14:00-14:30 Nils P Krone Varda Shalev Molecular Pathogenesis of Rare Forms Big Data: From Research to Value of CAH Director of research and innovation institute Academic Unit of Child Health Maccabi and Morris Kahn. Dep. of Oncology & Metabolism Tel Aviv university, Sackler School of University of Sheffield; Sheffield Children’s Medicine Hospital, Western Bank, UK 14:30-15:00 Naomi Weintrob1, David Zangen2 Shiri Salomon Genotype DOES Predict Phenotype Changing the Landscape of in CAH Secondary to 21 -Hydroxylase Osteoporosis- Artificial Intelligence to Deficiency- The Israel Experience Detect at-Risk Individuals 1Department of Pediatrics, Meir Medical Zebra Medical Vision Center 2Hadassah Medical Center 15:00-15:30 Adi Mory Eran Atlas 21-Hydroxylase Deficiency, Insights The Emerging “Digital Diabetes -Clinic” from the Molecular Lab and Implication CEO, DreaMed Diabetes for the Clinic Genetic Laboratory, Rambam Health Care Campus 8 April 7-8, 2019, Hilton Tel Aviv Hotel The 48th Annual Meeting of the Israel Endocrine Society 15:30-15:50 Coffee Break 15:50-16:50 Meet the Expert Hall A Meet the Expert Hall B Novel Avenues in the Management of Endocrine Hypertension Congenital Adrenal Hyperplasia Felix Beuschlein Nils P Krone University Hospital of Zurich Sheffield, UK 16:50-17:30 IES Members General Assembly Hall A Executive Committee Report Accountant Report Monday, April 8, 2019 07:30-08:00 Registration and Gathering 08:00-09:30 3 Parallel - Oral Presentations Bone Metabolism Diabetes, Basic and Neuroendocrinology and Chairs: Pnina Rotman, Clinical Adrenal Yankel Gabet Chairs: Sigal Shaklai, Chairs: Ester Osher, Amir Tirosh Ilan Shimon Hall A Hall B Hall C 09:30-09:50 Coffee Break 09:50-10:40 Plenary lecture 2 Hall A Felix Beuschlein, The ESE Lecture Recent Advances in Deciphering the Genetic Basis of Endocrine Hypertension University Hospital of Zurich Chair: Naftali Stern Parallel Symposia 10:40-12:10 Symposium 3 Hall A Symposium 4 Hall B Lipids, Inflammation and New Directions in Growth Hormone-IGF1 Atherosclerosis - What’s new? Research Chair: Hilla Knobler, Hofit Cohen Chair: Haim Werner, Yona Greenman 10:40-11:10 Ira Goldberg John Kopchick Diabetes, Lipids, and GH Effects on Fat in Humans and Mice; Macrovascular Complications Cellular Impact and ‘Big Data’ NYU School of Medicine, NYU Edison Biotechnology Institute, Ohio University; Langone Health, USA Athens, OH, USA 11:10-11:40 Hilla Knobler Gil Atzmon Lipoprotein a: When to Measure “ Longevity: is taller better?” and How to Treat? University of Haifa and Albert Einstein College of Diabetes, Endocrinology & Medicine, NY Metabolism Institute, Kaplan Medical Center, Rehovot 11:40-12:10 Yehuda Kamari Ehud Cohen Targeting Inflammation for The Role of the IGF1 Pathway in Prevention of Recurrent Neurodegenerative Disorders: Mechanisms Cardiovascular Events and Therapeutic Opportunities Sheba Medical Center, Ramat Gan The Hebrew University of Jerusalem 8 April 7-8, 2019, Hilton Tel Aviv Hotel The 48th Annual Meeting of the Israel Endocrine Society 9 12:10-12:20 Prizes for the Best Abstracts and Posters Hall A 12:20-13:10 Plenary lecture 3 John Kopchick, Ohio University Growth Hormone, Mini-mice, Football, Dirty Shorts, and a New Drug Chair: Zvi Laron 13:10-14:10 Lunch Parallel Symposia 14:10-15:40 Symposium 5 Hall A Symposium 6 Hall B Mechanisms of Metabolic Surgery Central Control of Reproductive Function and Incretin Therapies for Diabetes and Chairs: Philippa Melamed, Adi Avrech Obesity Chair: Gil Leibowitz, Benjamin Glaser 14:10-14:40 Danny Ben Zvi Philippa Melamed Sleeve Gastrectomy Improves Glycemia Early-life Stress and Effects on Independent of Weight Loss Adult Reproductive Function The Hebrew University of Jerusalem Faculty of Biology; Technion Institute of Technology, Haifa 14:40-15:10 Sigal Fishman Manuel Tena-Sempere GIP Regulation of Body Weight and Metabolic-Reproductive Connections: Inflammation Molecular Basis for Disordered Puberty in Sourasky Medical Center, Tel Aviv Malnutrition and Obesity Physiology Section, Faculty of Medicine University of Cordoba, Spain 15:10-15:40 Ofri Mosenzon Dalit Modan The Present and Future of Incretin Gonadotropins Role in Mediating the Therapies for Obesity and Diabetes Medical Complications of Anorexia Nervosa The Diabetes Unit Hadassah University Hospital, Pediatric Endocrinology and Diabetes Unit; The Ein Kerem; Jerusalem Edmond and Lily Safra Children’s Hospital, Sheba Medical Center 15:40-15:50 Coffee Break 15:50-16:50 Meet the Expert: Lipid disorders Hall A Ira Goldberg NYU School of Medicine, NYU Langone Health 10 April 7-8, 2019, Hilton Tel Aviv Hotel 12:10-12:20 Prizes for the Best Abstracts and Posters Hall A 12:20-13:10 Plenary lecture 3 John Kopchick, Ohio University Growth Hormone, Mini-mice, Football, Dirty Shorts, and a New Drug Chair: Zvi Laron 13:10-14:10 Lunch Parallel Symposia 14:10-15:40 Symposium 5 Hall A Symposium 6 Hall B Mechanisms of Metabolic Surgery Central Control of Reproductive Function and Incretin Therapies for Diabetes and Chairs: Philippa Melamed, Adi Avrech Obesity Chair: Gil Leibowitz, Benjamin Glaser 14:10-14:40 Danny Ben Zvi Philippa Melamed Sleeve Gastrectomy Improves Glycemia Early-life Stress and Effects on Independent of Weight Loss Adult Reproductive Function The Hebrew University of Jerusalem Faculty of Biology; Technion Institute of Technology, Haifa 14:40-15:10 Sigal Fishman Manuel Tena-Sempere GIP Regulation of Body Weight and Metabolic-Reproductive Connections: Inflammation Molecular Basis for Disordered Puberty in Sourasky Medical Center, Tel Aviv Malnutrition and Obesity Physiology Section, Faculty of Medicine University of Cordoba, Spain 15:10-15:40 Ofri Mosenzon Dalit Modan The Present and Future of Incretin Gonadotropins Role in Mediating the Therapies for Obesity and Diabetes Medical Complications of Anorexia Nervosa The Diabetes Unit Hadassah University Hospital, Pediatric Endocrinology and Diabetes Unit; The Ein Kerem; Jerusalem Edmond and Lily Safra Children’s Hospital, Sheba Medical Center PROGRAM 15:40-15:50 Coffee Break 15:50-16:50 Meet the Expert: Lipid disorders Hall A Ira Goldberg NYU School of Medicine, NYU Langone Health 10 April 7-8, 2019, Hilton Tel Aviv Hotel SUNDAY, APRIL 7, 2019 07:30-08:30 Registration and Gathering 08:30-10:00 Thyroid Hall A Chairs: Dania Hirsch, Carlos Benbassat 08:30 Thyroidectomy & Parathyroidectomy: TransOral Endoscopic TransVestibular Approach (TOETVA) Avi Hefetz, Niddal Assadi, Eran Alon A.R.M Clinics, A.R.M Otolaryngology Head and Neck & Maxilloficial Surgery 08:42 Urinary Iodine Content (UIC) and its Correlation to Maternal and Neonatal Thyroid Functions in Israel Tal Schiller1, Hilla Knobler1, Arnon Agmon2, Viviana Ostrovsky1, Taiba Zornitzki1 1Diabetes, Endocrinology and Metabolism Unit, Kaplan Medical Center 2Lev Tel-Aviv Women’s Health Center, Clalit Health Services 08:54 Thyroid Dysfunction and Mortality in Cardiovascular Hospitalized Patients – A 12 years Follow-up Observational Study Meir Frankel1, Feras Bayya2, Rivka Farkash2, Michael Glikson2, Gabriel Munter1 1Endocrinology Unit, Shaare-Zedek Medical Center 2Cardiology Department, Shaare-Zedek Medical Center 09:06 Thyroglobulin and Anti-thyroglobulin Antibodies Following Lobectomy: Implications for Response to Therapy Restaging System Amit Ritter2,4, Gideon Bachar2,4, Ilan Shimon1,4, Dania Hirsch1,4, Carlos Benbassat3,4, Talia Diker-Cohen1,4, Hadar Duskin-Bitan1,4, Eyal Robenshtok1,4 1Endocrinology Institute, Rabin Medical Center 2Department of Otorhinolaryngology, Head and Neck Surgery, Rabin Medical Center 3Endocrine Institute, Assaf Harofeh Medical Center 4Sackler Faculty of Medicine, Tel Aviv University 09:18 Response to Therapy Assessment in Intermediate-Risk Differentiated Thyroid Cancer Patients – Is rhTSH Stimulation Required? Itamar Moreno2, Ilan Shimon1,2, Dania Hirsch1,2, Carlos Benbassat2,3, Eyal Robenshtok1,2 1Endocrinology Institute, Rabin Medical Center 2Sackler Faculty of Medicine, Tel Aviv University 3Endocrinology Department, Assaf Harofeh Medical Center 09:30 PD-L1 Expression in Normal Endocrine Tissues Maayan Kagan3, Rena Pollack1, Rivka Dresner-Pollak1, Tzahi Neuman2