Seized Drugs Standard Operating Procedures Comparative and Analytical Division Seized Drugs Standard Operating Procedures Comparative and Analytical Division Table of Contents 1. Goals and Objectives ................................................................................................................................8 1.1. Goals.............................................................................................................................................8 1.2. Objectives.....................................................................................................................................8 2. Evidence Handling ..................................................................................................................................10 2.1 Scope..........................................................................................................................................10 2.2. Receiving and Documenting Evidence.............................................................................................10 2.3. Cases Containing Currency, Valuables, Large Items, and Bullets.....................................................12 2.4. Cases Requiring Examination for Latent Prints................................................................................12 2.5. Cases Containing Possible Biohazards .............................................................................................12 2.6. Return of Evidence to the Submitting Agency.................................................................................13 2.7. Related Documents .........................................................................................................................13 3. Analysis Guidelines .................................................................................................................................14 3.1. Scope ...............................................................................................................................................14 3.2. Safety...............................................................................................................................................14 3.3. Procedure ........................................................................................................................................14 3.4. Sampling Guidelines ........................................................................................................................15 3.5. Basic Analytical Scheme (Powders, Liquids, Tar and Chunk Substance)..........................................17 3.6. Drug Residues ..................................................................................................................................19 3.7. Plant Substance and Plant Substance Residues...............................................................................20 3.8. Tablets and Capsules – General.......................................................................................................22 3.9. Pharmaceutical Tablets and Capsules .............................................................................................23 3.10. Clandestine Tablets and Capsules..................................................................................................24 3.11. No Controlled Substance Identification.........................................................................................24 3.12. Literature and Supporting Documentation ...................................................................................25 3.13. Related Documents .......................................................................................................................25 4. Case Documentation ..............................................................................................................................26 4.1. Scope ...............................................................................................................................................26 4.2. Contents of Case Folder...................................................................................................................26 4.3. Technical Review .............................................................................................................................27 4.4. Administrative Review.....................................................................................................................27 Standard Operating Procedures Document ID: 2923 Issued By: Section Manager Issue Date: September 9, 2019 Uncontrolled When Printed Page 2 of 122 Seized Drugs Standard Operating Procedures Comparative and Analytical Division 4.5. Technical and Administrative Review Documentation....................................................................28 4.6. Report Modification Records...........................................................................................................29 4.7. Page Numbering of Examination Documents..................................................................................29 4.8. Related Documents .........................................................................................................................29 5. Seized Drugs Worksheets .......................................................................................................................30 5.1. Scope ...............................................................................................................................................30 5.2. Examination Sheet...........................................................................................................................30 5.3. Notes Sheet .....................................................................................................................................34 5.4. Cannabis sativa L. Checklist .............................................................................................................34 5.5. Related Documents .........................................................................................................................35 6. Instrument Performance and Maintenance ...........................................................................................36 6.1. Scope ...............................................................................................................................................36 6.2. General Requirements for Analytical Instrumentation ...................................................................36 6.3. UV/VIS Spectrophotometer.............................................................................................................36 6.4. FTIR Spectrometer...........................................................................................................................37 6.5. Gas Chromatography/Flame Ionization Detector (GC/FID) (Rescinded July 2018) .........................37 6.6. Gas Chromatography/Mass Spectrometry (GC/MS) .......................................................................37 6.7. Balances...........................................................................................................................................38 6.8. Pipettes (Rescinded July 2018) ........................................................................................................40 6.9. Malfunction of an Instrument, Pipet, or Balance ............................................................................40 6.10. Related Documents .......................................................................................................................40 7. Gas Chromatography (GC) for Quantitation of Codeine in Liquids (Rescinded July 2018).....................41 8. Gas Chromatography/Mass Spectrometry (GC/MS) ..............................................................................42 8.1. Scope ...............................................................................................................................................42 8.2. Safety...............................................................................................................................................42 8.3. Equipment, Materials, and Reagents...............................................................................................42 8.4. Standards, Controls, and Calibration...............................................................................................42 8.5. Procedure ........................................................................................................................................43 8.6. Limitations .......................................................................................................................................46 8.7. Advantages ......................................................................................................................................46 8.8. Literature and Supporting Documentation .....................................................................................46 8.9. Related Documents .........................................................................................................................47 Standard Operating Procedures Document ID: 2923 Issued By: Section Manager Issue Date: September 9, 2019 Uncontrolled When Printed Page 3 of 122 Seized Drugs Standard Operating Procedures Comparative and Analytical Division 9. Fourier Transform Infrared (FTIR) Spectrometry....................................................................................48