Brand to Generic switches Original Product Strength Pack Size Cost per Change to Pack size Cost per Savings per Notes Annual month month month savings/ pack 15mg £25.83 £1.63 £24.20 £314.60 Actos® tablets 30mg 28 £35.89 Pioglitazone tablets 28 £1.90 £33.99 £441.87 45mg £39.55 £2.62 £36.93 £480.09 2mg £3.58 £1.13 £2.45 £127.40 7 7 4mg £3.88 £0.86 £3.02 £157.04 Amias® tablets 8mg £9.89 Candesartan tablets £1.53 £8.36 £108.68 16mg 28 £12.72 28 £1.57 £11.15 £144.95 32mg £16.13 £1.97 £14.16 £184.08 75mg £9.69 £3.07 £6.62 £86.06 Aprovel® tablets 150mg 28 £11.84 Irbesartan tablets 28 £5.78 £6.06 £78.78 300mg £15.93 £5.84 £10.09 £131.17 10mg £51.13 Leflunomide tablets 10mg £4.79 £46.34 £556.08 Arava® tablets 30 30 20mg £61.36 Leflunomide tablets 20mg £4.83 £56.53 £678.36 30mg £13.99 £4.68 £9.31 £121.03 60mg £20.11 £3.03 £17.08 £222.04 Arcoxia® tablets 28 Etoricoxib tablets 28 90mg £22.96 £2.99 £19.97 £259.61 120mg £24.11 £12.35 £11.76 £1,328.88 5mg £59.85 £1.38 £58.47 £760.11 Aricept® tablets 28 Donepezil tablets 28 10mg £83.89 £2.42 £57.43 £746.59 5mg £59.85 Donepezil orodispersible sugar free £9.38 £50.47 £656.11 Aricept Evess® tablets 28 28 10mg £83.89 tablets £10.43 £73.46 £954.98 Arimidex® tablets 1mg 28 £68.56 Anastrazole tablets 28 £1.85 £66.71 £867.23 Aromasin® tablets 25mg 30 £88.80 Exemestane tablets 30 £33.52 £55.28 £663.36 5mg £96.04 £1.38 £94.66 £1,230.58 10mg £96.04 £1.57 £94.47 £1,228.11 Arpoya® tablets 28 Aripiprazole tablets 28 15mg £96.04 £1.74 £94.30 £1,225.90 30mg £192.08 £13.57 £178.51 £2,320.63 Audmonal® capsules £14.80 £6.73 £87.49 60mg 100 Alverine citrate capsules 100 £8.07 Spasmonal® capsules £16.45 £8.38 £108.94 Bondronat® tablets 50mg 28 £183.69 Ibandronic acid tablet 28 £43.11 £140.58 £1,827.54 Bonviva® tablets 150mg 1 £18.40 Ibandronic acid tablet 1 £4.27 £14.13 £169.56 1mg £10.56 £1.04 £9.52 £123.76 Cardura® tablets 28 Doxazosin tablets 28 2mg £14.08 £1.08 £13.00 £169.00 50mg £119.79 £4.10 £115.69 £1,503.97 Casodex® tablets 28 Bicalutamide tablets 28 150mg £240.00 £6.24 £233.76 £3,038.88 Cholurso® tablets 250mg £18.00 £5.42 £65.04 Annual cost saving calculated on 1bd dose. 60 Ursodeoxycholic acid capsules 60 £12.58 Please note, this is also a formulation change. Ursofalk® capsules 250mg £30.17 £17.59 £211.08 5mg £18.03 £1.42 £16.61 £215.93 10mg £18.03 £1.59 £16.44 £213.72 Crestor® tablets 28 Rosuvastatin tablets 28 20mg £26.02 £2.12 £23.90 £310.70 40mg £29.69 £2.52 £27.17 £353.21 2.5mg £54.99 £26.95 £28.04 £364.52 28 28 5mg £54.99 £5.36 £49.63 £645.19 Prescriptions for generic or branded tadalafil are Cialis® tablets Tadalafil tablets required to meet the SLS criteria for NHS prescribing 10mg £28.88 £1.34 £27.54 £358.02 4 4 Please see NHSE LVM data re tadalafil and 5mg 20mg £28.88 £1.72 £27.16 £353.08 5mg £8.97 £1.33 £7.64 £99.32 Cipralex® tablets 10mg 28 £14.91 Escitalopram tablets 28 £1.40 £13.51 £175.63 20mg £25.21 £1.55 £23.66 £307.58 150mg/12.5mg £11.84 £10.87 £0.97 £12.61 Please refer to MHRA alert on long-term use of CoAprovel® tablets 300mg/12.5mg 28 £15.93 Irbesartan/hydrochlorothiazide tablets 28 £5.35 £10.58 £137.54 hydrochlorothiazide -switch away from 300mg/25mg £15.93 £7.20 £8.73 £113.49 hydrochlorothiazide where possible Colofac® tablets 135mg 100 £9.02 Mebeverine tablets 100 £4.90 £4.12 £53.56 12.5mg £9.70 £5.70 £4.00 £52.00 25mg £16.18 £1.42 £14.76 £191.88 Cozaar® tablets 28 Losartan tablets 28 50mg £12.80 £1.61 £11.19 £145.47 100mg £16.18 £1.97 £14.21 £184.73 50mg/12.5mg £12.80 £1.59 £11.21 £145.73 Please refer to MHRA alert on long-term use of Cozaar-Comp® tablets 100mg/12.5mg 28 £16.18 Losartan/hydrochlorothiazide tablets 28 £12.09 £4.09 £53.17 hydrochlorothiazide -switch away from hydrochlorothiazide where possible 100mg/25mg £16.18 £1.82 £14.36 £186.68 30mg £22.40 £1.74 £20.66 £268.58 Cymbalta® capsules 28 Duloxetine capsules 28 60mg £27.72 £2.36 £25.36 £329.68 1mg £29.03 £14.02 £15.01 £195.13 Detrusitol® tablets 56 Tolterodine tablets 56 2mg £30.56 £14.56 £16.00 £208.00 Difflam® spray 0.15% 30ml £4.24 Benzydamine hydrochloride spray £2.78 £1.46 £17.52 Ebixa® tablets 10mg £34.50 £2.83 £31.67 £411.71 or 28 Memantine tablets 28 Nemdatine® tablets 20mg £69.01 £7.19 £61.82 £803.66 Ebixa® oral solution sugar- free or 10mg/ml 50ml £61.61 Memantine oral solution sugar-free 50ml £16.55 £45.06 £585.78 Savings calculated per 50ml bottle Ebixa® 5mg/0.5ml pump actuation oral solution 75mg £22.08 £2.60 £19.48 £253.24 Efexor® XL capsules 28 Venlafaxine MR capsules 28 150mg £36.81 £3.90 £32.91 £427.83 5mg £47.56 Prasugrel tablets 5mg £9.49 £38.07 £494.91 Efient® tablets 28 28 10mg £47.56 Prasugrel tablets 10mg £5.98 £41.58 £540.54 30g £4.80 30g £3.24 £1.56 £20.28 Elocon® cream 0.1% Mometasone cream 0.1% 100g £15.10 100g £10.80 £4.30 £55.90 30g £4.32 30g £2.96 £1.36 £17.68 Elocon® ointment 0.1% Mometasone ointment 0.1% 100g £12.44 100g £9.87 £2.57 £33.41 Evista® tablets 60mg 28 £17.06 Raloxifene tablets 28 £5.39 £11.67 £151.71 Ezetrol® tablets 10mg 28 £26.31 Ezetimibe 10mg tablets 28 £2.51 £23.80 £309.40 Femara® tablets 2.5mg 30 £90.92 Letrozole tablets 14 £2.98 £87.94 £1,055.28 Please check if suitable to advise patient to purchase Flixonase® nasal spray 50mcg 150dose £11.01 Fluticasone Furoate nasal spray 27.5mcg 120 dose £6.44 £4.57 £59.41 the 50mcg spray OTC. Not applicable to IESCCG Flomaxtra® XL tablets 400mcg 30 £10.47 Tamsulosin MR capsules 30 £2.77 £7.70 £100.10 10mg 28 £23.12 28 £7.62 £15.50 £201.50 Fosamax® tablets Alendronic acid tablets 70mg 4 £22.80 4 £0.99 £22.57 £293.44 50mg £31.85 £1.40 £30.45 £395.85 Imigran® tablets 6 Sumatriptan tablets 6 100mg £51.48 £1.56 £49.92 £648.96 5mg £11.08 £1.00 £10.08 £131.04 Istin® tablets 28 Amlodipine tablets 28 10mg £16.55 £1.03 £15.52 £201.76 Lamisil® tablets 250mg 14 £21.30 Terbinafine tablets 14 £1.70 £19.60 £509.60 Lamisil® cream 1% 30g £7.45 Terbinafine cream 30g £3.72 £3.73 £44.76 200mg £14.23 £3.51 £10.72 £139.36 Lipantil Micro® capsules 28 Fenofibrate (micronised) 28 267mg £21.75 £4.37 £17.38 £225.94 10mg £13.00 £1.00 £12.00 £156.00 20mg £24.64 £1.40 £23.24 £302.12 Lipitor® tablets 28 Atorvastatin tablets 28 40mg £24.64 £1.42 £23.22 £301.86 80mg £28.21 £2.03 £26.18 £340.34 10mg £11.16 £1.13 £10.03 £130.39 28 28 Losec® capsules 20mg £16.70 Omeprazole capsules £1.18 £15.52 £201.76 See also dose optimisation for 40mg capsules 40mg 7 £8.35 7 £0.88 £29.88 £388.44 50mg £17.82 £4.39 £13.43 £174.59 Lustral® tablets 28 Sertraline tablets 28 100mg £29.16 £8.88 £20.28 £263.64 20mg £11.10 £2.40 £8.70 £113.10 Micardis® tablets 40mg 28 £13.61 Telmisartan tablets 28 £3.44 £10.17 £132.21 80mg £17.00 £4.33 £12.67 £164.71 Migard® tablets 2.5mg 6 £16.67 Frovatriptan tablets 6 £5.51 £11.16 £133.92 88mcg £11.24 £3.59 £7.65 £91.80 180mcg £22.49 £2.23 £20.26 £243.12 Mirapexin tablets 30 Pramipexole tablets 30 350mcg £44.97 £13.90 £31.07 £372.84 700mcg £89.98 £2.27 £87.71 £1,052.52 0.26mg £32.49 £29.82 £2.67 £32.04 0.52mg £64.98 £35.94 £29.04 £348.48 1.05mg £129.96 £64.01 £65.95 £791.40 Mirapexin® MR tablets 1.57mg 30 £202.36 Pramipexole MR tablets 30 £185.75 £16.61 £199.32 2.1mg £259.91 £238.45 £21.46 £257.52 2.62mg £337.27 £186.85 £150.42 £1,805.04 3.15mg £389.87 £357.79 £32.08 £384.96 Movicol® sachets 13.125g 30 £8.11 £3.69 £44.28 Macrogol 13.125g sachets 30 £4.42 Transisoft® sachets 8.5g 28 £39.85 £39.85 £478.20 30mg £125.75 £82.97 £42.78 £556.14 Please check with GP if appropriate for individual Mimpara® tablets 60mg 28 £231.97 Cinacalcet tablets 28 £146.54 £85.43 £1,110.59 patients due to indication and possibility of difference 90mg £347.96 £219.82 £128.14 £1,665.82 in bioavailability Mucodyne® capsules 375mg 120 £18.98 Carbocisteine capsules 120 £5.11 £13.87 £180.31 Naramig® tablets 2.5mg 6 £24.55 Naratriptan tablets 6 £3.01 £21.54 £280.02 Please check if suitable to advise patient to purchase Nasonex® nasal spray 50mcg 140dose £7.68 Mometasone nasal spray 140 dose £4.62 £3.06 £39.78 OTC, or alternative beclometasone/fluticasone nasal spray OTC 20mg £18.50 £2.62 £15.88 £206.44 Nexium® tablets 28 Esomeprazole tablets 28 40mg £25.19 £4.00 £21.19 £275.47 10mg £10.95 £3.22 £7.73 £100.49 Olmetec® tablets 20mg 28 £12.95 Olmesartan tablets 28 £2.54 £10.41 £135.33 40mg £17.50 £3.33 £14.17 £184.21 One-Alpha® capsules 1mcg 30 £8.75 Alfacalcidol capsules 30 £4.55 £4.20 £50.40 10mg £5.78 £1.52 £4.26 £55.38 Pariet® tablets 28 Rabeprazole tablets 28 20mg £11.34 £1.77 £9.57 £124.41 Plavix® tablets 75mg 30 £35.64 Clopidogrel tablets 28 £1.62 £34.02 £408.24 30g £25.92 30g £22.20 £3.72 £44.64 Protopic® ointment 0.1% Tacrolimus ointment Savings calculated on one pack per month 60g £47.28 60g £44.40 £2.88 £34.56 Provigil® tablets 100mg 30 £52.60 Modafinil tablets 30 £3.35 £49.25 £640.25 Renagel® tablets 800mg 180 £167.04 Sevelamer tablets 180 £42.28 £124.76 £1,621.88 500mcg £5.08 £1.38 £3.70 £48.10 20 20 1mg £8.36 £1.61 £6.75 £87.75 2mg £34.62 £3.84 £30.78 £369.36 Risperdal® tablets Risperidone tablets 3mg 60 £50.91 60 £4.86 £46.05 £552.60 4mg £67.20 £5.12 £62.08 £744.96 6mg 28 £67.88 28 £49.21 £18.67 £224.04 25mg £48.60 £2.08 £46.52 £558.24 100mg £135.72 £4.33 £131.39 £1,576.68 Seroquel® tablets 60 Quetiapine tablets 60 200mg £135.72 £5.22 £130.50 £1,566.00 300mg £204.00 £6.11 £197.89 £2,374.68 10mg 28 £14.21 28 £4.57 £9.64 £125.32 Seroxat® tablets 20mg 30 £15.23 Paroxetine tablets £1.74 £13.49 £161.88 30 30mg 30 £26.74 £2.22 £24.52 £294.24 4mg £25.69 Montelukast chewable tablets sugar- £2.12 £23.57 £306.41 Singulair® Paediatric tablets 28 28 5mg £25.69 free £2.01 £23.68 £307.84 Singulair® tablets 10mg 28 £26.97 Montelukast tablets 28 £2.54 £24.43 £317.59 Singulair®