010 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 Program January, August 6, 2012 8:30 – 9:00 Registration 9:00 – 9:10 Opening CCC 2012 Chairman: Prof. Qizhen Du 9:10 – 9:20 Welcome speech from the director of Zhejiang Gongshang University Session 1 – CCC Keynotes Chirman: Prof. Guoan Luo pH-zone-refining countercurrent chromatography : USA 09:20-09:50 Ito, Y. Origin, mechanism, procedure and applications K-1 Sutherland, I.*; Hewitson. P.; Scalable technology for the extraction of UK 09:50-10:20 Janaway, L.; Wood, P; pharmaceuticals (STEP): Outcomes from a year Ignatova, S. collaborative researchprogramme K-2 10:20-11:00 Tea Break with Poster & Exhibition session 1 France 11:00-11:30 Berthod, A. Terminology for countercurrent chromatography K-3 API recovery from pharmaceutical waste streams by high performance countercurrent UK 11:30-12:00 Ignatova, S.*; Sutherland, I. chromatography and intermittent countercurrent K-4 extraction 12:00-13:30 Lunch break 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 January, August 6, 2012 Session 2 – CCC Instrumentation I Chirman: Prof. Ian Sutherland Pro, S.; Burdick, T.; Pro, L.; Friedl, W.; Novak, N.; Qiu, A new generation of countercurrent separation USA 13:30-14:00 F.; McAlpine, J.B., J. Brent technology O-1 Friesen, J.B.; Pauli, G.F.* Berthod, A.*; Faure, K.; A small volume hydrostatic CCC column for France 14:00-14:20 Meucci, J.; Mekaoui, N. full and quick solvent selection O-2 Construction of a HSCCC apparatus with Du, Q.B.; Jiang, H.; Yin, J.; column capacity of 12 or 15 liters and its China Xu, Y.; Du, W.; Li, B.; Du, application as flash countercurrent 14:20-14:40 O-3 Q.* chromatography in quick preparation of (-)-epicatechin 14:40-15:30 Tea Break with Poster & Exhibition session 2 Session 3 – CCC Instrumentation II Chirman: Prof. Guido Pauli Steady-state and non-steady state operation of Russia 15:30-15:50 Kostanyan, A. E. countercurrent chromatography devices O-4 True moving bed CPC for continuous France 15:50-16:10 G. Audo*; Le Quémeneur, C. purification of natural substances O-5 Goll, J.; Frey, A.; Minceva, Design of a continuous centrifugal partition Germany 16:10-16:30 M.* chromatography O-6 Hewitson, P.*; Sutherland, I.; Intermittent countercurrent extraction: Scale up UK 16:30-16:50 Wood, P.; Ignatova, S. and an improved bobbin design O-7 18:00-19:30 Welcome dinner at a restaurant 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 February, August 7, 2012 Session 4 – CCC Theory I Chirman: Prof. Alain Berthod Selection of the mobile and stationary phase in Germany 09:00-09:20 Frey, A.*; Minceva, M. support free liquid-liquid chromatography applying a predicative thermodynamic model O-8 Schwienheer, C.*; Selection and use of aqueous two phase systems Germany 09:20-09:40 Adelmann,S.; Merz, J.; in centrifugal partition chromatography Schembecker, G. O-9 Modeling counter-current chromatography using China 09:40-10:00 Wei, Y.*; Wang, F.; Wang, S. a temperature dependence plate model O-10 China, Wu, S. ; Wu, D. ; Liang, J. ; Modeling gradient elution in CCC: Efficient 10:00-10:20 France Berthod, A.* separation of tanshinones O-11 12:40-11:20 Tea Break with Poster & Exhibition session 3 Session 5 – CCC Theory II Chirman: Prof.: Peter Winterhalter Merz, J.*; Schwienheer, C.; Investigation of hydrodynamics in CPC Germany 11:00-11:20 Adelmann, S.; Schembecker, chambers using image processing and G. computational fluid dynamics O-12 Research of interaction between ionic and tea Chen, X.; Huang, X.; Wang, polyphenols by computer simulation assisted China 11:20-11:40 G.; Zhang J.; Di, D. * high-performance counter-current O-13 chromatography Modeling of step wise gradients in HSCCC; A Shehzad, O.; Khan, S.; Ha, rapid and economical strategy for one step Korea 11:40-12:00 I.J.; Lee, K.J.; Tosun, A.; separation of eight dihydropyranocoumarins Kim, Y.S.* O-14 from Seseli resinousm. 12:00-13:30 Lunch break 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 February, August 7, 2012 Session 6 – CCC Application I (Room A) Chirman: Prof. Xueli Cao Winterhalter, P.*; Jerz, G.; Isolation of bioactive polyphenols from Germany 13:30-13:50 Kuhnert, S.; Juadjur, A.; by-products of food processing using Macke,S. countercurrent chromatography O-15 Chen, X.; Huang, X.; Wang, Study on preparative separation and purification China 13:50-14:10 X.; Shi, M.; Wang, G.; of chemical compounds from plants by HSCCC Zhang, J.; Di, D.* O-16 Enantioseparation of 2-phenylpropionic acid by Zheng, Y.; Tong, S. Q.*; Yan, recycling high-speed countercurrent China 14:10-14:30 J. Z. chromatography using hydroxypropyl-β- O-17 cyclodextrin as chiral selector Excellent fraction effect of HSCCC on the Jin,Y. Y.; Qian, D. Y.; Du, Q. China 14:30-14:50 completed separation of amide compounds in Z.* black pepper O-18 Session 7 – CCC Application II (Room B) Chirman: Prof. Eiichi Kitazume Multifunctional tetranor triterpenoids from Hummel, H. E.*; Hein, D. F.; Azadirachta indica : A separation challenge Germany 13:30-13:50 Ma, Y.; Ito, Y. solved by MLCCC at both the analytical and O-19 preparative scale Bioassay guided separation of bioactive components in natural products via China 13:50-14:10 Hu, R.; Chen, P.; Pan, Y.* countercurrent chromatography coupled with O-20 LC/MS/MS He, Z. C.; Ye, Q. X.; Wu, Separation and purification of quanternary J.Y.; Yang, D. P.; Brown, L.; China 14:10-14:30 protoberberine alkaloids from Corydalis Jiang, L.; Zhu, L. P.; Wang, saxicola Bunting by HSCCC O-21 D. M.* Separation and purification of four lignans from Yang, M.; Xu, X.*; Xie, Z.; China 14:30-14:50 Fructus arctii by high-speed countercurrent Huang, J.; Xie, C. chromatography O-22 14:50-15:30 Tea Break with Poster & Exhibition session 4 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 February, August 7, 2012 Session 8 – CCC Application III (Room A) Chirman: Prof. Hans E. Hummel Separation andenrichment of rare earth elements Shibukawa, M.*; Shimizu, by stepwise pH gradient countercurrent Japan 15:30-15:50 K.; Saito, S. chromatography with a polyethylene O-23 glycol-Na2SO4 aqueous two-phase system Application of high-speed countercurrent Ma, J.; Niu, L.; Cai, X.; Ito, China 15:50-16:10 chromatography, TLC and LC-MS/MS in Y.; Yang, F. lipidomics O-24 Isolation of two new diterpenoids from Xu, M.; Du, Q.;* Shen, L.; Clerodendrum kaichianum hsu. by high-speed China 16:10-16:30 Wang, H. counter-current chromatography using stepwise O-25 elution Wang, K. B.; Liu, F.; Liu, Preparative isolation of Oolong tea polyphenols by China 16:30-16:50 Z.L.*, Huang, J. A.; Lin, high-speed countercurrent chromatography Y.; Gong, Y. S. O-26 Session 9 – CCC Application IV(Room B) Chirman: Prof. Artak Kostanyan Ramos, R. E.; Pauli, G. F.; Generation of knock-out extracts by USA 15:30-15:50 Chen, S. N.* countercurrent chemical subtraction O-27 Rapid separation of polyphenols from green tea by Wang, W.*; Le, S.; Zhao, X; China 15:50-16:10 HSCCC and characterization the interaction Wang, T.; Zhang, J. between EGCG and protein by ACE O-28 Online isolation and purification of four phthalide compounds from Rhizome chuanxiong using China 16:10-16:30 Wei, Y.*; Huang, W. countercurrent chromatography coupled with semipreparative high performance liquid O-29 chromatography He, M.; Du, W.; Du, Q.B.; Separation of 11-cis-retinal from the retinal China 16:30-16:50 Zhang, Y.; Li, B.; Ke, C. ; isomers by flash countercurrent chromatography Du, Q.* O-30 18:00-19:30 Gala dinner at a restaurant 7th international conference on countercurrent chromatography, Hangzhou, August 6-8, 2012 Wendesday, August 8, 2012 Session 10 – CCC Application V (Room A) Chirman: Prof. John B. Friesen Qiu, F.; Samuel Pro, NMR-guided countercurrent purification and USA 09:00-09:20 S. ; Pauli, G. F.; Friesen, J. O-31 B.* quantification of green tea catechins O-31 Yin, L.; Cao, X. L.*; Xu, J.; Separation of bioactive components from China 09:20-09:40 Gynura divaricata (L.) DC by high-speed O-32 Cheng, C.; Pei, H. R. countercurrent chromatography O-32 Combination of high-speed countercurrent Wang, D.J., Du, J. H.*; Lin, Chromatography and Preparative HPLC to China 09:40-10:00 Separation of Flavonoid Glycosides and O-33 Y. L.; Li, S. B.; Wang, X. Caffeoylquinic Acid Derivatives from Leaves of O-33 Lonicera japonica Thunb. Preparative separation of conjugated linoleic 10:00-10:20 Song, G.L.; Wang, J.B.; acids (CLA) from camellia oleifera abel using China 10:00-10:20 Wang, Y.B.; Du, Q.Z.* pH-zone-refining counter-current O-34 chromatography Session 11 – CCC Application VI (Room B) Prof. Yuanjiang Pan From medicinal plant to compound: isolation of Hu, P.; Liu, M.; Zhang, M.;* shikimic acid from Illicium verum by China 09:00-09:20 Hua, Y.; Zhang, H.; Wang, hyphenated expanded bed adsorption O-35 Y.; Luo, G.* chromatography and counter-current O-35 chromatography Comprehensive separation of lignans from Lu, Y. B.*; Lin, X. J.; Wang, Zanthoxylum planispinum by countercurrent China 09:20-09:40 chromatography combined with O-36 K.W. high-performance liquid chromatography/ O-36 tandem mass spectrometry Wang , X.; Dong, H. J.; Large-scale separation of alkaloids from China 09:40-10:00 Yang, B.; Lin, X. J.; Huang, corydalis bungeana turca.by pH-zone-refining O-37 L. Q.* counter-current chromatography O-37 Zhu, Y.; Zhan, Y.; Gui, H.; Separation of the synthetic products of China 10:00-10:20 acetylated rhein by high-speed counter-current O-38 Wei, Q.; Liu, Y.; Xu, T.* chromatography O-38 10:20-11:20 Tea Break with Poster & Exhibition session 5 Closing remarks, Edward Chou and Crafty Chromatographer Award 11:20-11:40 ceremony Prof.