FINAL PROGRAM TRANSLATING REPRODUCTIVE SCIENCE TO THE BEDSIDE Vancouver Convention Centre East 999 Canada Pl Vancouver, BC, Canada V6C 3C1 SRI-1019-633 The SRI 67th Annual Scientific Meeting is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada, and approved by Society of Obstetricians and Gynaecologists of Canada. VANCOUVER MARCH 10-14, 2020 - Vancouver Convention Centre East 1 Table of Contents Message from the SRI President . 1 SRI Membership Recognition Program Ads . 2 SRI Mentor Hall of Fame . 5 2020 Program Committee . 6 General Meeting Information . 7 Meeting Attendance Code of Conduct Policy . 8 Schedule-at-a-Glance . 9 Social Events . 10 Exhibitors . 11 Vancouver Convention Centre East and Host Hotels Map . 12 Vancouver Convention Centre East Level 1 Map . 13 Vancouver Convention Centre East Level 2 Map . 14 Continuing Medical Education Information . 15 Scientific Program . 16 Thank You to Our 2020 Poster Judges . 60 SRI Grant Opportunities . .61 2020 Awards . 62 About SRI…………………………… . 64 2019 – 2020 Annual Report . 66 SRI Council & Staff . 68 Poster Guide . 69 Oral and Poster Abstract Author Index . 108 Notes . 131 Thank You to Our 2020 Supporters . Inside. Back Cover Save the Date: SRI 2021 Annual Meeting . Back Cover SRI 67th Annual Scientific Meeting Venue Vancouver Convention Centre East 999 Canada Pl Vancouver, BC V6C 3C1 Canada SRI 67th Annual Scientific Host Hotels Pan Pacific Hotel Vancouver • 300-999 Canada Pl Fairmont Waterfront Hotel • 900 Canada Pl Fairmont Pacific Rim • 1038 Canada Pl Future SRI Annual Scientific Meetings SRI 68th Annual Scientific Meeting • Boston, MA • March 23 – 27, 2021 SRI 69th Annual Scientific Meeting • Denver, CO • March 15 – 19, 2022 SRI 70th Annual Scientific Meeting • Brisbane, QLD, Australia • March 21 - 25, 2023 2 SOCIETY FOR REPRODUCTIVE INVESTIGATION - 67th Annual Scientific Meeting Message from the SRI President and Program Director Dear Colleagues: Welcome to the 67th Annual Meeting of the Society for Reproductive Investigation (SRI), March 10 – 14, 2020 in Vancouver, BC, Canada . The theme of the 2020 is meeting, “Translating Reproductive Science to the Bedside .” With Irina Burd, MD, PhD, as Program Director, we have developed an outstanding program that includes Presidential Distinguished Lecturers, a New Investigator Plenary, Oral Sessions, Invited Mini-Symposia, Invited Lunch and Learn Symposia and a Hot Topics Plenary . Moreover, the 2020 Program is packed with several career development sessions and networking opportunities, such as the Career Development Workshops, including a new Grant Writing Clinic; New Investigator, Early and Mid-Career sessions; and the popular “Connection Corners ”. This year, the Diversity, Equity and Inclusion Forum has been placed on Thursday, over the lunch hour, giving all delegates the option to attend . Of course, your very own SRI Band, The Featles, will be back for their Canadian Tour! The meeting will feature exciting and inspiring presentations by leading scientists . Our first Presidential Distinguished Lecturer will be Joan A. Steitz, PhD . Prof . Steitz is the Sterling Professor of Molecular Biophysics & Biochemistry at Yale University . She is internationally recognized for her work in discovering and establishing the structures and functions of non-coding (nc)RNAs in vertebrate (mostly mammalian) cells . In 2018, Prof . Steitz was awarded the Lasker-Koshland Special Achievement in Medical Science Award not only for her leadership in RNA biology, but also for her dedication to scientific training, as she has trained almost 200 scientists either as postdoctoral fellows or PhD students . Prof . Steitz will be speaking on March 13th at 8:00 a .m . Our second Presidential Distinguished Lecturer will be Janet Rossant, CC, PhD, FRS, FRSC . Prof . Rossant is a Professor in the Department of Molecular Genetics, University of Toronto . She is internationally recognized as a trailblazer for her work on cell fate in embryo development and stem cells . Her research has opened new vistas in reproduction . Prof . Rossant has received numerous awards including the 2007 March of Dimes Prize in Developmen- tal Biology, and is an inspiration and mentor to many scientists in the field of reproduction . Dr . Rossant will deliver her presentation on March 14th at 8:00 a .m . Furthermore, for the first time, the SRI meeting in Vancouver will host the Annual March of Dimes Prize in Developmental Biology and the Agnes Higgins Award . The March of Dimes Developmental Biology Prize recipient will be named in March 2020 . Past recipients of the March of Dimes Prize in Developmental Biology include highly distinguished scientists that have transformed their fields and several have later become Nobel Laureates . The recipient of this prestigious award will deliver a presentation at the 2020 SRI meeting on March 12th at 8:00 a .m . The recipients of the Agnes Higgins Award will also be announced . The SRI has offered several travel awards for the Annual Meeting . All awardees will be acknowledged during differ- ent sessions throughout the Annual Meeting . True to the nature of our Society, the 67th Annual SRI Meeting will be highly collegial and provide a forum for outstanding science and the opportunity for fruitful global networking . On behalf of the SRI Council, Program Committee, and Staff, we welcome you to Vancouver! Sincerely Yours, James Segars, MD Irina Burd, MD, PhD SRI President, 2019-2020 SRI Program Director, 2020 VANCOUVER MARCH 10-14, 2020 - Vancouver Convention Centre East 1 Member Recognition Program Members of SRI took this opportunity to recognize a member of SRI publically in exchange for a donation to the SRI Foundation . Thank you to all those who participated! Laura T Dr. Robert Garfield Goldsmith, PhD A legend in the field of preterm birth A generous mentor who encouraged and Wonderful scientist and colleague fostered many young investigators and National leader in resident and always remained a friend for life fellow research education A big thank you! Tireless advocate for women in SRI — Dr . Linda Chambliss — Nanette Santoro, MD Sandy Davidge Murray Mitchell Sandy, the work you accomplished for SRI Murray, thank you for your fore vision has changed our trajectory for the better. and work with the Society. We are so Thank you for all you have done! grateful for your dedication to SRI. — SRI Council — SRI Council 2 SOCIETY FOR REPRODUCTIVE INVESTIGATION - 67th Annual Scientific Meeting There once was a man from Oregon With deep gratitude: Who dreamed of becoming — The One Kristina A.W. To unite the clinic and science David E. And find answers to guide us Kara H. He found it was perfectly fun Sophia L. Stephen M. You may think that this story’s absurd Sarah W. But there’s more – he’s a joker – I heard Christie W. Starting with preterm birth Alisa K. Jumping to proteomics And ending up as a global health nerd Now his mark on us all is not small We learned to write, tell a story – not scrawl But the craziest part Are his continuous pranks That come to an unsuspecting meatball The lesson he is trying to impart Is to keep science simple – it’s an art What an honor it would be To end up like he With such a legacy of science and heart Irina Burd I could never thank you enough for all the work you have done to make this week possible. I couldn’t have done it without you. — Jim Segars VANCOUVER MARCH 10-14, 2020 - Vancouver Convention Centre East 3 Anne Krolikowski Leah Miller Thanks for all you do! Thanks for all you do! — SRI Council — SRI Council Michelle Holm Thanks for all you do! — SRI Council 4 SOCIETY FOR REPRODUCTIVE INVESTIGATION - 67th Annual Scientific Meeting Morgan Derby Ciera Arias Thanks for all you do! Thanks for all you do! — SRI Council — SRI Council SRI Mentor Hall of Fame The SRI leadership realizes that the society is nothing without its members and we want to recognize your contributions . In 2019, in an effort to recognize SRI’s best Mentors, as well as raise funds for the SRI Foundation, voting was open to the Membership for just $25 per vote . Members of SRI were encouraged to team up with their peers and raise the most funds in the name of their favorite mentor . 2020 Mentor Hall of Fame Inductee: Gerson Weiss, MD Honorable Mention: Anne Colston Wentz, MD | Gary Hodgen, PhD | Hugh Taylor, MD | Norman Gant, MD | Zev Rosenwaks, MD VANCOUVER MARCH 10-14, 2020 - Vancouver Convention Centre East 5 2020 Program Committee Program Committee Chair 2020 Program Director Emre Seli, MD Irina Burd, MD, PhD Yale School of Medicine Johns Hopkins University Sarah K. England, PhD Bo R. Rueda, PhD Washington University School of Medicine MGH / Harvard Medical School Ayman Al-Hendy, MD, PhD Floor Spaans, PhD University of Illinois at Chicago Department of University of Alberta Obstetrics and Gynecology James H. Segars, MD Charles A. Ducsay, PhD Johns Hopkins University School of Medicine Loma Linda University Nanette F. Santoro, MD Thomas Jansson, MD, PhD University of Colorado University of Colorado Anschutz Medical Campus Dineo Khabele, MD Leslie Myatt, PhD, FRCOG The University of Kansas Medical Center Oregon Health and Science University Tourism Vancouver 6 SOCIETY FOR REPRODUCTIVE INVESTIGATION - 67th Annual Scientific Meeting General Meeting Information Meeting Description The SRI Annual Meeting gathers leading scientists and clinical investigators annually to share cutting-edge information in reproductive