PRODUCT DATA SHEET Bioworld Technology,Inc. CEP76 polyclonal antibody Catalog: BS62332 Host: Rabbit Reactivity: Human,Mouse,Rat BackGround: IHC: 1:50~1:200 Centrosomes are the major microtubule-organizing cen- Storage&Stability: ters of mammalian cells. They are composed of a centri- Store at 4°C short term. Aliquot and store at -20°C long ole pair and surrounding microtubule-nucleating material term. Avoid freeze-thaw cycles. termed pericentriolar material (PCM). Bipolar mitotic Specificity: spindle assembly relies on two intertwined processes: CEP76 polyclonal antibody detects endogenous levels of centriole duplication and centrosome maturation. Failure CEP76 protein. to properly orchestrate centrosome duplication and matu- DATA: ration is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP76 (centrosomal protein of 76 kDa) gene en- codes a protein of 659 amino acids. The CEP76 protein is homologous among several species including human, mouse, rat and xenopus, suggesting a conserved function. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, Western blot (WB) analysis of CEP76 polyclonal antibody at 1:500 di- 50% glycerol, pH7.2 lution Molecular Weight: LaneA:COS-7 whole cell lysate ~ 76 kDa LaneB:PC3 whole cell lysate Swiss-Prot: LaneC:CT26 whole cell lysate Q8TAP6 LaneD:PC12 whole cell lysate Purification&Purity: Note: The antibody was affinity-purified from rabbit antiserum For research use only, not for use in diagnostic procedure. by affinity-chromatography using epitope-specific im- munogen and the purity is > 95% (by SDS-PAGE). Applications: WB: 1:500~1:1000 Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add： 1660 South Highway 100, Suite 500 St. Louis Park, Add： No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151 .