GDF10, Growth differentiation factor 10 poly- clonal antibody rowth differentiation factor 10 (GDF10) is a member of or Research Use Only. Not for Gthe bone morphogenetic protein (BMP) family and the FDiagnostic or Therapeutic Use. TGF-beta superfamily. BMP proteins are secreted growth Purchase does not include or carry factors that are characterized by seven conserved cysteine any right to resell or transfer this residues. In general, they are regulators of cell growth and product either as a stand-alone product or as a component of another differentiation in both embryonic and adult tissues. GDF10 product. Any use of this product other seems to play a role in skeletal morphogenesis. than the permitted use without the express written authorization of Allele Biotech is strictly prohibited Buffers Purified rabbit polyclonal antibody supplied in PBS with Website: www.allelebiotech.com 0.09% (W/V) sodium azide. This antibody is purified through Call: 1-800-991-RNAi/858-587-6645 a protein G column and eluted out with both high and low pH (Pacific Time: 9:00AM~5:00PM) buffers and neutralized immediately after elution then fol- Email: [email protected] lowed by dialysis against PBS. Box 1 | Basic Info Immunogen Cat. No. ABP-PAB-10690 KLH conjugated synthetic peptide comprised of amino acids 48 - 62 [DGLQGDRDLQRHPGD] of the human growth dif- Animal ID RB1873-1874 ferentiation factor 10 (GDF10) protein. Host Rabbit Reactivity Human Format Purified Accession number NM_004962 Application 100µg Amount Tested by peptide-specific ELISA (1:1,000). WB (1:100 ~1:500), IHC (1:50 ~1:100) Alternative Name(s): BMP3B, bone morphogenetic protein 3B, GDF10 Storage Maintain refrigerated at 2-8ºC for up to 6 months. For long term storage store at -20ºC. Avoid repeated freeze-thaw cycles. References: 1. Ducy P, Karsenty G: The family of bone morphogenetic proteins. Kidney Int. 57(6): 2207-2214 (2000). Review. 2. Hino J, Takao M, Takeshita N, Konno Y, Nishizawa T, Matsuo H, Kangawa K: cDNA cloning and genomic structure of human bone morphogenetic protein-3B (BMP-3b). Biochem. Biophys. Res. Commun. 223(2): 304-310 (1996). 3. Cunningham NS, Jenkins NA, Gilbert DJ, Copeland NG, Reddi AH, Lee SJ: Growth/ differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors 12(2): 99-109 (1995). Allele Biotech-Introducing Cost Effectiveness to Research.