Newsletter A publication of the Controlled Release Society Volume 27 • Number 1 • 2010 What’s Inside New C&DP Representative Joins Newsletter Board Portland Awaits Phase Separation Behavior of Fusidic Acid in Microspheres Tailoring In Vitro Cell Responses of Porous Silicon Nanoencapsulation Using Microfluidizer® Processors Gamma Scintigraphy and Canine Respiratory Models News from the CRS Focus Groups CRS-AAPS Workshop a Success C&DP Patent Watch IT’S ALL ABOUT THE CONTENT That’s why subscribers of Drug Delivery Technology spend 40 minutes reading each issue. Drug Delivery Technology is the only publication completely dedicated to product development. Highlight your message to our 20,000 subscribers through print and online marketing opportunities! Y 10 printed issues Y eNewsletter sent twice per month, featuring the latest news CONTACT US TODAY shaping the industry (lim ited to 5 sponsors per month) EAST & MIDWEST Victoria Geis • Tel: (703) 212- 7735 • [email protected] Y Website Banner Advertising WEST Y Webinars and webcasts Warren DeGraff • Tel: (415) 721-0664 • [email protected] INTERNATIONAL Y Listings in the Resource Directory Ralph Vitaro • Tel: (973) 263-5476 • [email protected] (All listings in print and the digital WEBINARS version posted online) Michael J. Masters • 973-299-1200 • [email protected] Newsletter Steven Giannos Vol. 27 • No. 1 • 2010 Editor Table of Contents From the Editor .................................................................................................................. 2 From the President ............................................................................................................ 3 Editorial Board Bozena Michniak-Kohn Starting Thoughts from the C&DP Representative to the CRS Newsletter Editor Editorial Board ..................................................................................................................... 4 37th CRS Annual Meeting & Exposition ......................................................................... 6 Scientifically Speaking Phase Separation Behavior of Fusidic Acid in Microspheres Influences Morphology and Drug Release ........................................................................................... 8 Tailoring In Vitro Cell Responses of Porous Silicon Micro- and Nanoparticles .................. 10 Yvonne Perrie Spotlight Editor Nanoencapsulation Using Microfluidizer® Processors Via “Top Down” and “Bottom Up” Processing Methods .................................................................................... 12 Gamma Scintigraphy: A Useful Tool in Canine Respiratory Models .................................. 14 From the Vet Group A New Title in Veterinary Drug Delivery ............................................................................ 16 Chapter News Rod Walker UKICRS Symposium 2010 .................................................................................................. 18 Editor CRS Illinois Student Chapter Holds ‘80s Game Night ....................................................... 18 Joint Meeting of PAT2009 and the CRS Israeli Chapter .................................................... 19 Welcome CRS Student Chapter The Hebrew University of Jerusalem .............................. 20 CRS Italian Chapter ........................................................................................................... 20 CRS New Zealand and Australian Chapters Hold Workshop on “Improving the Bioavailability of Poorly Water-Soluble Drugs” ........................................ 21 Satellite Workshops Arlene McDowell CRS-AAPS Satellite Workshop a Resounding Success ...................................................... 23 Editorial Board CRS Focus Groups News from the CRS Nanomedicine Focus Group ............................................................. 25 CRS Oral Drug Delivery Focus Group Update .................................................................. 27 Patent Watch ................................................................................................................... 28 In the News ..................................................................................................................... 33 Event Calendar ........................................................................................................ Cover 4 Charles Frey Editorial Board Advertisers’ Index Drug Delivery Technology ...................................................................................... Cover 2 Elsevier ............................................................................................................................... 5 SMi .................................................................................................................................... 32 1 From the Editor Editors Arlene McDowell Steven Giannos Bozena Michniak-Kohn New Zealand’s National School of Yvonne Perrie Pharmacy, Univerity of Otago Rod Walker Dunedin, New Zealand Editorial Board Arlene McDowell (Vet Group) Charles Frey (C&DP) Publications Committee Chair elcome to the first issue of the CRS Newsletter for the new decade. We wish Ijeoma Uchegbu you a very happy new year! And, to represent the international nature of our Society—W gung hay fat choy, jour des étrennes, gutes nue Jahr, say hay boke-mahn he pah The CRS Newsletter is the official newslet- du say oh, and godt nytår. I have fond memories of my family and the new year ter of the Controlled Release Society. The newsletter is published five times annually tradition of “first-footing.” This is a European tradition, where to bring good luck a providing scientific and technical informa- male with dark hair must be the first person to enter the house, preferably with a tion pertinent to the controlled release piece of coal, saying, “Lang may your lum reek” (“Long may your chimney smoke”). community and news about society and My father had dark hair, and so he was a popular visitor on new year’s day. There are chapter activities. Members can receive the newsletter via mail. The newsletter many lovely traditions around the world surrounding the new year, and a great CRS may also be viewed online at tradition is the annual meeting. Our CRS Annual Meeting & Exposition in 2010 www.controlledreleasesociety.org. will be held in Portland, OR—“The city of roses.” This will help some of you solve Newsletter articles reflect only the views the little mystery of why all those people had red roses on their name badges at the of the authors. Publication of articles or 2009 CRS Annual Meeting. The meeting organising committee thanks those who advertisements within the CRS Newsletter have agreed to be abstract reviewers for the CRS Annual Meeting in Portland. does not constitute endorsement by the Controlled Release Society or its agents Abstract reviewing is a very important part of the meeting, and we appreciate the of products, services, or views expressed time and effort that goes into ensuring that the high standard of podium and poster herein. No representation is made as to presentations is maintained. the accuracy hereof and the publication is printed subject to errors and omissions. The CRS Newsletter continues to grow and provide increased communication with Editorial contributions should be directed to the CRS Newsletter Editors, our members. With six issues planned for 2010, there is lots of great reading to come. ([email protected]) and are As always, we welcome your contributions. Please contact a member of the CRS subject to the terms and conditions of Newsletter Editorial Board if you would like to submit an article or have any the Editorial and Publication Release. suggestions about the Newsletter. We are also giving members the opportunity to Publisher assumes no responsibility for the safety or return of artwork, photographs, promote images of their controlled release science on the cover of the CRS or manuscripts. Newsletter. If you have a great image you would like to share, we would love to see it. Requests for advertisement placement may Send electronic copies through the online dropbox at http://dropbox.yousendit.com/ be directed to Debby Woodard, Business scisoc (see page 15 in this issue for more details). Development Department; telephone +1.651.994.3817, or e-mail at dwoodard@ In this issue you can read about the activities of a number of CRS Chapters scisoc.org. All advertisements are subject to “General Conditions of Sale.” worldwide, including a new Student Chapter at The Hebrew University of Jerusalem and be at the right place at the right time for the UKI CRS symposium in April, Unauthorized reproduction in whole or in part is prohibited. Requests for permission where you will find out about controlled release in drug delivery. I encourage you to should be directed to the Editors at seek out a Chapter located near you and get involved. Plus check out our regular [email protected]. forums, including Scientifically Speaking, Patent Watch, From the Vet Group, and In ©Copyright 2010 Controlled Release the News. Society. All rights reserved. Controlled Release Society On behalf of the editorial team of the CRS Newsletter, I wish you a happy, healthy, 3340 Pilot Knob Road and successful 2010. St. Paul, MN 55121 U.S.A. Telephone: +1.651.454.7250 Best wishes, Facsimile: +1.651.454.0766 n Visit www.controlledreleasesociety.org or Arlene McDowell e-mail [email protected] on questions about membership, meetings, publications, and services. Contact [email protected] for