BOOK CHAPTER - OPEN ACCESS International Journal Of Medicine And Healthcare Reports Contents lists available at bostonsciencepublishing.us International Journal Of Medicine And Healthcare Reports The Concept of Entomotoxicology is Now Being Reviewed Vaibhav Gawade * Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India. ARTICLE INFO ABSTRACT Article history: Up until now, the term “entomotoxicology” it was only to be used for medical and legal sciences. Received 26 June 2021 However, entomotoxicology, in general, has a much broader scope and field of entomotoxicology Revised 03 July 2021 is the only one of its affiliates. On the basis of the literature and a broader definition of the term, Accepted 22 July 2021 is presented. Today, there are two main areas of entomotoxicology: 1) Forensic entomotoxicology, Available online 31 July 2021 the use of insects as evidence of the presence of xenobiotics in the fusion of the tissues during the investigation, and (2) Environment entomotoxicology, the use of insects as bio-indicators of pollution Keywords: in the environment, in non-criminal situations. Although forensic entomotoxicology is a relatively new Forensic Entomotoxicology field of research in the field of the environment entomotoxicology began as early as the 1920’s. The Environment Entomotoxicology article provides an overview of the activities in the field of entomotoxicology is the last of 6 years, Xenobiotics with many new areas of interest. This article aims to review entomotoxicology, which should lead to a greater awareness of collaboration and interdisciplinarity in between in related scientific fields. © 2021, . Gawade.V.S. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited 1. Introduction opportunities for co-operation between the different areas is reduced, The possibility to remove the buildup of toxins in the bodies of and the foot, which leads to further isolation as in other related fields. insects, it is well-known [1-3]. In the presence of certain xenobiotics Therefore, in order to clarify the terminology used, it may lead to: (1) (e.g. drugs, insecticides, insect repellents, and heavy-duty metal) in a to standardize the procedures of the forensic entomotoxicology, and (2) particular area, such as a landscape, a river, you may have an important the expansion of knowledge on the effects of the drug and its prepa- role to play in the analysis of the following habitats. In some cases, it is rations, on the insects and their environment, in the environment of desirable, or even inevitable, for the use of insects as evidence of the entomotoxicology. In this article, based on the available literature, a contamination. Insects may help us to detect xenobiotics, but it can also definition, and the use of the term, entomotoxicology is presented. To be used as a model to investigate the effects of specific xenobiotics in better characterize the range of the current view, the focus of this study the target insect species. How to xenobiotics may be quite different, is on the most recent research, in particular, since 2012. An overview as well as the specific research objectives that they are in. However, of the entomotoxicological studies on the effects of insecticides and all these studies have covered a wide range of entomotoxicology. The repellents, and the presence of the heavy metals present in the insect’s word of entomotoxicology is a combination of the words are from the bodies, as well as the traditional research in criminology, is presented. Greek: “entomon” to mean “insect”, “toxikos” means “ poisonous “and 2. The New Fields of Entomotoxicology “ logos” is the object. So, etymologically, is the field of the science of Campbell [5], it is proposed that the term “Insect Toxicology” as xenobiotics acting on the insect. The term was first used by pounder a new term for all of the studies conducted on the effects of insec- in 1991. Pounder [4] is used with the appropriate level of care, and the ticides on insects as early as in 1926. The Insect toxicity have to be addition of the adjective “samples”, that is, in itself, should give you synonymous with the term “ entomotoxicology, however, it has never a broader definition of the term. However, up to now, no one in par- been used. Pounder [4] that are defined in forensic entomotoxicology, ticular, found the missing part of the application of entomotoxicology, as the detection of illegal drugs in a decaying body, through the analy- and the term is exclusively used for the research, the arts and scienc- sis of fly larvae (“larvae”) power supply. The term “ entomotoxicology es. There has been a lot of research in the field of entomotoxicology, has become popular and is now used in virtually all of the articles are that is never to be considered as entomotoxicological, however, it is devoted to the study of the elimination of toxins within the body of intended to be the accumulation of xenobiotics in the body of insects the insect, for scientific and regulatory purposes. However, the phrase and their biological effects. Because of the strange terminology, and was further developed in 1994, Goff, and of the Lord, [6] evaluated in entomotoxicology, as is the use of insect specimens, on the basis of the acute shortage of tissues and fluids, is usually taken for the purpose from the dead to the study. However, the adjective, the court and it is * Corresponding author. therefore recommended that, entomotoxicology is the only medical-le- Mr. Gawade.V.S., Assistant Professor, Department of Pharmaceutical chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences & Research. Mobile No: +918830699204 E-mail address: [email protected] 1 BOOK CHAPTER - OPEN ACCESS Gawade.V.S. / International Journal Of Medicine And Healthcare Reports gal approaches. A lot of other authors have repeated a similar approach ious concepts they will be able to respond differently to the same type Gawade.V.S to [7-17], while other authors to evaluate their private areas, such as of xenobiotic [20]. An important role of entomotoxicology the judicial entomotoxicology [18-23]. which is defined in forensic entomotoxicolo- system is not the cause of his death [13, 18-20]. From 1977 to 2017, gy as is the use of insect specimens as an additional source of evidence with 63 research papers in forensic entomotoxicology, where [19]. Even 2(2);1-4 Rep, Int J Med Healthcare is Now Being Reviewed. (2021) The Concept of Entomotoxicology for the lack of direct evidence, such as blood, urine, soil, or water, in though the value of the forensic entomotoxicology for the review and to the presence of a xenobiotic in the environment, which might be a dead determine the cause of death, that is, it may be of interest in this area body in a river, or even a landscape [19]. They are divided into forensic is still quite poorly known. A number of limitations, and differences entomotoxicology (1) environmental forensic entomotoxicology, that is, between the studies were identified [19]. There is a lack of methodolog- the focus is on the use of insects as bio-indicators of environmental tox- ical standardization is necessary in order to make comparisons between icants, and (2) Medico-legal forensic entomology, which is focused on the studies; (2) the Majority of studies have reported an insufficient the use of insects as a placeholder or is mediated sampling, where the number of iterations, which increases the risk of errors in statistical bodies were often come to the toxicity of the sample. Article da Silva, inference; (3) the Effective entomotoxicological research can be costly, the trend towards a more precise definition of this field is, however, just which means that validation of the wider relevant, however, it is often like most of the other authors, they are supposed entomotoxicology not possible; and (4) the Majority of the studies have been carried out, within the medical and legal boundaries [18]. have already made use or by an entomologist, or a toxicologist. However, both the entomolog- of the terminology proposed [19], who observed that the insect can ical and ecological approach, however, is equally important and must be also be used as a direct evidence of heavy metal contamination in the carefully controlled so as not to miss important information. Campo- vicinity of industrial areas, or antidepressant medication, pollution of basso et al. [18], it was concluded that one of the main weaknesses in the river, the body of such a study. However, in the field, entomotox- the field, the correlation between the levels of xenobiotics in the young, icology includes studies not only for academic purposes but also for and in the number found on the body. The interpretation of the results all other types of ecological studies of insects have been studied, for is hampered by our poor knowledge of the metabolism of xenobiotics example, the effects of the use of insecticides and insect repellents, or in insects the unknown, the influence of environmental factors on the with the accumulation of the heavy metals present in the insect bodies. determination of xenobiotics, and different concentrations of medicinal Therefore, the scope of entomotoxicology is much broader than has substances in a variety of tissues, and a diverse sampling method [18, previously been recognized. A few of its most important tasks include 20]. In addition to animals, it can produce different metabolites than problem-solving: (1) the ability of the trust, the detection of xenobiot- men, which can lead to incorrect assumptions [12]. ics; (2) the quantitative relationship between the number of xenobiotics derived from the insect’s body, and the amount of power supply and/or the environment, to be found in the body of the insect; and 3) the effect of the presence of xenobiotics in the body.