HANDBOOK www.agtaconference.org CONTENTS Welcome 5 General Information 6 Conference Program 10 Social Program 24 Abstracts and Biographies 28 Poster Presentations 82 Sponsorship & Exhibition 126 Delegate List 140 Image credit: Tourism Tasmania & Rob Burnett Cover images: Tourism Tasmania & Rob Burnett (Top right & bottom left), Daniel Tran (bottom right) Discover robust tools to advance your genome research Alt-R™ CRISPR-Cas9 System • Higher on-target potency than other CRISPR systems • Easier transfection with nucleic acids and a size-optimized plasmid • Consistently reliable results—no toxicity or activation of innate immune response as observed with in vitro transcribed Cas9 mRNA and sgRNAs • Safe, fast protocol with no lengthy and hazardous viral particle preparation See the data at www.idtdna.com/CRISPR-Cas9. For Research Use Only. Not for use in diagnostic procedures. © 2017 Integrated DNA Technologies, Inc. All rights reserved. Trademarks contained herein are the property of Integrated DNA Technologies, Inc. or their respective owners. For specifi c trademark and licensing information, see www.idtdna.com/trademarks. 2017 AGTA Conference Page: 3 AGTA17 ORGANISING AGTA EXECUTIVE TEAM COMMITTEE Dr Jac Charlesworth (AGTA17 Convenor) University of Tasmania Dr Jac Charlesworth (Convenor) University of Tasmania Associate Professor Nicole Cloonan (Resigned) The University of Auckland Dr Kathryn Burdon University of Tasmania Dr Rob Day University of Otago Associate Professor Ruby Lin University of New South Wales Associate Professor Marcel Dinger Garvan Institute of Medical Research Ms Vikki Marshall Dr Kate Howell (Resigned) The University of Melbourne University of Western Australia Dr Carsten Kulheim ' (Vice-President, Resigned) CONFERENCE MANAGERS Australian National University Associate Professor Ruby CY Lin Leishman Associates University of New South Wales 227 Collins Street, Prof Ryan Lister Hobart TAS 7000 University of Western Australia 170 Elgin Street, Carlton VIC 3053 Ms Vikki Marshall (Secretary) The University of Melbourne P. 03 6234 7844 | F. 03 6234 5958 E. [email protected] Associate Professor Alicia Oshlack Murdoch Childrens Research Institute W. www.leishman-associates.com.au Dr Andreas Schreiber SA Pathology Dr Kirby Siemering Australian Genome Research Facility Dr Helen Speirs Ramaciotti Centre for Genomics Professor Rik Thompson (Lifetime Honorary Executive) Queensland University of Technology Dr Richard Tothill The University of Melbourne Mr Mark van der Hoeke (Treasurer) South Australian Health and Medical Research Institute Dr Mark Waltham (President) The University of Melbourne Mr Liam Williams The University of Auckland Image credit: Paul Fleming 2017 AGTA Conference Page: 4 WELCOME FROM THE CONFERENCE CONVENOR On behalf of the Australasian Genomic Technologies Association and the organising committee it is my pleasure to welcome you to the 2017 AGTA Annual Conference at the Hotel Grand Chancellor in Hobart, Tasmania. It is clear from the program that we are in the midst of an exciting time for genomic technologies. The pre- conference workshops on gene editing and single-cell sequencing highlight the emerging technologies that are already reshaping the genomic landscape. The 2017 program is brimming with incredible science and we hope you make the most of having all these inspiring people in one place. One of the strengths of AGTA conferences is the engagement with our generous sponsors. This meeting would not be possible without their support. Special thanks to our Gold sponsor BGI and Silver sponsor Illumina for their continued support. We also thank our returning sponsors and exhibitors and are pleased to welcome some new faces this year. We recognise that the interface between developers and users of genomic technologies is dynamic and that communication is integral to future advances – so make sure you visit them and take this opportunity to have those important conversations. I’m excited about so many things this year! We have shaken things up a little – making space in the program for more talks from abstracts, and giving voice to the next generation of genomic scientists. We have also worked hard to flip the gender balance, something this field has struggled with in the past. We have four incredible international speakers joining us this year – all great scientists who also happen to be women – and a well-balanced and inspiring line up of invited speakers representing the thriving Australasian genomics community. We’ve introduced lightning poster sessions – to give students and ECRs a chance to present their posters in a more dynamic and intense way. Our satchels are made by Freeset – a fair trade organisation providing employment and freedom to women trapped in the sex trade in India. They also feature two local icons – Kunanyi/Mt Wellington and the wedge-tailed eagle. On the social side, we will kick off with a Welcome Reception at The Hotel Grand Chancellor, our meeting headquarters, on the edge of Hobart’s historic waterfront. We’re helping you with your bucket list by holding the conference dinner at Mona, the iconic Museum of Old and New Art, known for its artworks, architecture, wine and feasts of fresh Tasmanian produce. We hope you can join us for entertainment, socialising and networking. Please enjoy the meeting and all that Hobart has to offer. Dr Jac Charlesworth, University of Tasmania 2017 AGTA Conference Page: 5 GENERAL INFORMATION REGISTRATION DESK CONFERENCE PROCEEDINGS Please direct any questions you may have Speaker PowerPoints will be available on the regarding registration, accommodation or social AGTA website following the conclusion of the functions to Leishman Associates staff at this conference. Speakers will be requested to sign a desk. release form. This is not compulsory. Registration Desk Opening Times: Sunday 29 October 2.00pm – 6.00pm Monday 30 October 7.30am – 5.30pm Tuesday 31 October 7.30am – 5.30pm CONFERENCE WIFI Wednesday 1 November 7.30am – 2.30pm Proudly sponsored by: ACCOMMODATION If you have any queries relating to your Wireless internet will be available throughout accommodation booking first speak to the the conference venue for the duration of the staff at your hotel or alternatively Leishman conference. Associates staff at the Registration Desk. Username: AGTA2017 Your credit card details were supplied to the Password: bgiwifi17 hotel you have selected, as security for your booking. If you have arrived 24 hours later than your indicated arrival day you may find that you have been charged a fee. You will be responsible for all room and incidental charges on check TWITTER out and may be asked for an impression of your credit card for security against these charges. Join the Conversation at: This is standard policy in many hotels. @agtaGenomics #AGTA17 DELEGATE NAME BADGES FAMILY ROOM All delegates, speakers, sponsors and exhibitors As an equity and diversity initiative in will be provided with a name badge, which support of delegates with parenting or caring must be worn at all times within the conference responsibilities, a private room will be available venue as it is required for access to all the at the conference venue for parents with conference sessions and social functions. young children. This room is also available for delegates to use as a quiet room if they require Proudly sponsored by: a breakout space from the Plenary or Trade. Live audio from the Plenary, along with presenter PowerPoint presentations, will be available to view from this room. 2017 AGTA Conference Page: 6 GENERAL INFORMATION DRESS CODE BARISTA COFFEE Dress throughout the day is smart casual or Barista coffee will be available throughout the informal business. conference in the Trade Exhibition Proudly sponsored by: EMERGENCY MEDICAL CARE For any medical emergency please telephone 000. The staff at your hotel will have information if you require contact details for a doctor, dentist or other health professional. SOCIAL PROGRAM ENTRY The Welcome Reception is included in the cost of each full conference registration. EXHIBITOR PRIZE DRAW The Conference Dinner IS NOT included in any registration type. Social events ARE NOT An exhibitor passport is included in the pocket included in the cost of day registrations or program that will be given to all delegates at for accompanying partners. Places for day registration. The AGTA17 organising committee registrants and additional guests for these encourages you to visit each trade exhibitor events may still be available at an additional and have your passport stamped, to go into the cost. Bookings can be made at the registration draw to win some great prizes! desk subject to availability. SATCHEL STUDENT FUNCTION Each attendee will receive a tote bag produced All conference students and early career by Freeset at registration. researchers are invited to a casual function on Tuesday 31 October at Shambles Brewery. If you would like to attend and have not pre-registered, please see Leishman Associates staff at the registration desk. Further information about this event can be found on page 24. More than a stitched piece of fabric, Freeset bags PROGRAM DIVERSITY tell a story of freedom. For hundreds of women trapped in bonded labour and human trafficking. We have worked hard to improve the gender Freeset is in the business of restoring what has balance for the 2017 meeting. 58% of our been stolen. Women given the opportunity to invited speakers are female (7/12) including all choose a new job and regain control of their lives four international invited speakers. This year in a caring community. Making Freeset Products we have opened the program to more invited is part of a women’s journey to freedom. To her abstracts. The program features 33 invited friends and neighbours among the thousands still abstract presentations, 48% of which are being trapped in the sex trade, she is a symbol of hope. given by students or ECRs. 2017 AGTA Conference Page: 7 GENERAL INFORMATION PHOTOGRAPHS, VIDEOS, ORAL PRESENTATIONS RECORDING OF SESSIONS Please refer to the program for the time allocated for each presentation, as these do Delegates are not permitted to use any type vary.