CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) Most recent changes to this medium descriptor document: • Addition of 8 Category I codes (0004A, 0051A, 0052A, 0053A, 0054A, 0064A, 91305, 91306) accepted by the CPT Editorial Panel. Codes 0004A, 0051A, 0052A, 0053A, 0054A, 0064A, 91305, 91306 and all related references will be published in CPT 2023. • Deleted codes in this document appear with a strikethrough. It is important to note that further CPT Editorial Panel or Executive Committee actions may affect these codes and/or descriptors. For this reason, code numbers and/or descriptor language in the CPT code set may differ at the time of publication. In addition, further Panel actions may result in gaps in code number sequencing. The following code was accepted at the March 2020 CPT Editorial Panel meeting for the 2021 CPT production cycle. This code is effective immediately on March 13, 2020. Released to Code Medium Code Descriptor Effective Publication AMA website ⚫87635 IADNA SARS-COV-2 COVID-19 AMPLIFIED PROBE TQ March 13, 2020 March 13, 2020 CPT® 2021 The following codes were accepted and revised at the April 2020 CPT Editorial Panel meeting for the 2021 CPT production cycle. These codes are effective immediately on April 10, 2020. IMMUNOASSAY INFECTIOUS AGT ANTIBODY 86318 QUAL/SEMIQUAN 1 STEP METH April 10, 2020 April 10, 2020 CPT® 2021 #⚫86328 IA INFECTIOUS AGT ANTIBODY SARS-COV-2 COVID-19 April 10, 2020 April 10, 2020 CPT® 2021 ⚫86769 ANTB SEVERE AQT RESPIR SYND SARS-COV-2 COVID- April 10, 2020 April 10, 2020 CPT® 2021 19 The following code was accepted by the Executive Committee of the CPT Editorial Panel. This code is effective immediately on June 25, 2020. CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 1 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) ⚫87426 IAAD IA SEVERE AQT RESPIR SYND CORONAVIRUS June 25, 2020 June 25, 2020 CPT® 2022 The following codes were accepted by the CPT Editorial Panel. These codes are effective immediately on August 10, 2020. #⚫86408 NEUTRALIZING ANTIBODY SARS-COV-2 SCREEN August 10, 2020 August 10, 2020 CPT® 2022 #⚫86409 NEUTRALIZING ANTIBODY SARS-COV-2 TITER August 10, 2020 August 10, 2020 CPT® 2022 The following codes were accepted by the CPT Editorial Panel. These codes are effective immediately on September 8, 2020. #⚫86413 SEV AQT RESPIR SYND CORONAVIRUS 2 ANTIBODY September 8, September 8, CPT® 2022 QUAN 2020 2020 ⚫99072 ADDL SUPL MATRL&STAF TM DRG PHE RES-TR NFCT DS September 8, September 8, CPT® 2022 2020 2020 The following codes were accepted, revised, and deleted by the CPT Editorial Panel. These codes are effective immediately on October 6, 2020. IAAD IA ADENOVIRUS ENTERIC TYP 40/41 87301 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA QUAL/SEMIQUAN MULTIPLE STEP 87305 October 6, 2020 October 6, 2020 CPT® 2022 ASPERGILLUS CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 2 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) IAAD IA CHLAMYDIA TRACHOMATIS 87320 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA CLOSTRIDIUM DIFFICILE TOXIN 87324 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA CRYPTOCOCCUS NEOFORMANS 87327 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA CRYPTOSPORIDIUM 87328 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA GIARDIA 87329 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA CYTOMEGALOVIRUS 87332 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA ESCHERICHIA COLI 0157 87335 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA ENTAMOEBA HISTOLYTICA DISPAR GRP 87336 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA ENTAMOEBA HISTOLYTICA GRP 87337 October 6, 2020 October 6, 2020 CPT® 2022 CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 3 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) IAAD IA HPYLORI STOOL 87338 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HPYLORI 87339 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HEPATITIS B SURFACE ANTIGEN 87340 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HEPATITIS B SURFACE AG NEUTRALIZATION 87341 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HEPATITIS BE ANTIGEN 87350 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HEPATITIS DELTA ANTIGEN 87380 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HISTOPLASM CAPSULATUM 87385 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HIV-1 AG W/HIV-1 & HIV-2 ANTBDY SINGLE 87389 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA HIV-1 87390 October 6, 2020 October 6, 2020 CPT® 2022 CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 4 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) IAAD IA HIV-2 87391 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA INFLUENZA A/B EACH 87400 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA RESPIRATORY SYNCTIAL VIRUS 87420 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA ROTAVIRUS 87425 October 6, 2020 October 6, 2020 CPT® 2022 ⚫ 87426 IAAD IA SEVERE AQT RESPIR SYND CORONAVIRUS October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA SHIGA-LIKE TOXIN 87427 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA STREPTOCOCCUS GROUP A 87430 October 6, 2020 October 6, 2020 CPT® 2022 IAAD IA MULT STEP METHOD NOSNOT OTHERWISE 87449 October 6, 2020 October 6, 2020 CPT® 2022 SPECIFIED EACH ORGANISM 87450 IAAD IA SINGLE STEP METHOD NOS EA ORGANISM October 6, 2020 October 6, 2020 CPT® 2022 CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 5 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) IAAD IA POLYV MLT ORGANISMS EA POLYV ANTISERUM 87451 October 6, 2020 October 6, 2020 CPT® 2022 ⚫87636 IADNA SARSCOV2& INF A&B MULT AMPLIFIED PROBE October 6, 2020 October 6, 2020 CPT® 2022 TQ ⚫87637 IADNA SARSCOV2 & INF A&B & RSV MULT AMP PROBE October 6, 2020 October 6, 2020 CPT® 2022 TQ IAADIADOO STREPTOCOCCUS GROUP B 87802 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO CLOSTRIDIUM DIFFICILE TOXIN A 87803 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO HIV1 ANTIGEN W/HIV1 & HIV2 ANTIBODIES #87806 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO INFLUENZA 87804 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO RESPIRATORY SYNCTIAL VIRUS 87807 October 6, 2020 October 6, 2020 CPT® 2022 #⚫87811 IAADIADOO SEVERE AQT RESPIR SYND CORONAVIRUS October 6, 2020 October 6, 2020 CPT® 2022 CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 6 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) IAADIADOO TRICHOMONAS VAGINALIS 87808 October 6, 2020 October 6, 2020 CPT® 2022 INFECTIOUS AGENT IMMUNOASSAY OPTICAL 87809 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO ADENOVIRUS IAADIADOO CHLAMYDIA TRACHOMATIS 87810 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO NEISSERIA GONORRHOEAE 87850 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO STREPTOCOCCUS GROUP A 87880 October 6, 2020 October 6, 2020 CPT® 2022 IAADIADOO NOT OTHERWISE SPECIFIED 87899 October 6, 2020 October 6, 2020 CPT® 2022 The following codes were accepted by the CPT Editorial Panel. *Note that resequenced code 87428 will follow code 87426 and is effective immediately on November 10, 2020. Codes 0001A, 0002A, and 91300 are effective December 11, 2020. Codes 0011A, 0012A, and 91301 are effective December 18, 2020. Codes 0031A, 91303 are effective February 27, 2021. Codes 0003A, 0013A are effective August 12, 2021. Codes 0004A, 0021A, 0022A, 0041A, 0042A, 0051A, 0052A, 0053A, 0054A, 0064A, 91302, 91304, 91305, and 91306 will be effective upon receiving Emergency Use Authorization or approval from the Food and Drug Administration. #⚫87428 IAAD IA SARSCOV & INFLUENZA VIRUS TYPES A&B November 10, November 10, 2020 2020 CPT® 2022 November 10, December 11, ⚫0001A IMM ADMN SARSCOV2 30MCG/0.3ML DIL RECON 1ST 2020 2020 ® DOSE CPT 2022 CPT © Copyright 2021 American Medical Association. All rights reserved. AMA and CPT are registered trademarks of the American Medical Association. Updated September 3, 2021 7 CPT® Category I and Proprietary Laboratory Analyses (PLA) Codes for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) November 10, December 11, 2020 2020 IMM ADMN SARSCOV2 30MCG/0.3ML DIL RECON 2ND ⚫0002A CPT® 2022 DOSE ⚫0003A IMM ADMN SARSCOV2 30MCG/0.3ML DIL RECON 3RD July 30, 2021 August 12, 2021 CPT® 2023 DOSE September 3, Effective upon CPT® 2023 ⚫0004A 2021 receiving IMM ADMN SARSCOV2 30MCG/0.3ML DIL RECON BST Emergency Use DOSE Authorization or approval from the Food and Drug Administration September 3, Effective upon CPT® 2023 2021 receiving #⚫0051A IMM ADMN SARSCOV2 30MCG/0.3ML TRIS-SUCROSE Emergency Use 1ST Authorization or approval from the Food and Drug Administration September 3, Effective upon CPT® 2023 2021 receiving #⚫0052A IMM ADMN SARSCOV2 30MCG/0.3ML TRIS-SUCROSE Emergency Use 2ND Authorization or approval from the Food and Drug Administration CPT © Copyright 2021 American Medical Association.