AHRQ Healthcare Horizon Scanning System – Status Update Horizon Scanning Status Update: April 2015 Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 540 Gaither Road Rockville, MD 20850 www.ahrq.gov Contract No. HHSA290-2010-00006-C Prepared by: ECRI Institute 5200 Butler Pike Plymouth Meeting, PA 19462 April 2015 Statement of Funding and Purpose This report incorporates data collected during implementation of the Agency for Healthcare Research and Quality (AHRQ) Healthcare Horizon Scanning System by ECRI Institute under contract to AHRQ, Rockville, MD (Contract No. HHSA290-2010-00006-C). The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services. A novel intervention may not appear in this report simply because the System has not yet detected it. The list of novel interventions in the Horizon Scanning Status Update Report will change over time as new information is collected. This should not be construed as either endorsements or rejections of specific interventions. As topics are entered into the System, individual target technology reports are developed for those that appear to be closer to diffusion into practice in the United States. A representative from AHRQ served as a Contracting Officer’s Technical Representative and provided input during the implementation of the horizon scanning system. AHRQ did not directly participate in the horizon scanning, assessing the leads or topics, or provide opinions regarding potential impact of interventions. Disclaimer Regarding 508-Compliance Persons using assistive technology may not be able to fully access information in this report. For assistance contact [email protected]. Financial Disclosure Statement None of the individuals compiling this information has any affiliations or financial involvement that conflicts with the material presented in this report. Public Domain Notice This document is in the public domain and may be used and reprinted without special permission. Citation of the source is appreciated. Suggested citation: ECRI Institute. AHRQ Healthcare Horizon Scanning System Status Update. (Prepared by ECRI Institute under Contract No. HHSA290-2010-00006-C) Rockville, MD: Agency for Healthcare Research and Quality. April 2015. http://www.effectivehealthcare.ahrq.gov/reports/final.cfm. i Preface The purpose of the AHRQ Healthcare Horizon Scanning System is to conduct horizon scanning of emerging health care technologies and innovations to better inform patient-centered outcomes research investments at AHRQ through the Effective Health Care Program. The Healthcare Horizon Scanning System provides AHRQ a systematic process to identify and monitor emerging technologies and innovations in health care and to create an inventory of emerging technologies that have the highest potential for impact on clinical care, the health care system, patient outcomes, and costs. It will also be a tool for the public to identify and find information on new health care technologies and interventions. Any investigator or funder of research will be able to use the AHRQ Healthcare Horizon Scanning System to select potential topics for research. The health care technologies and innovations of interest for horizon scanning are those that have yet to diffuse into or become part of established health care practice. These health care interventions are still in the early stages of development or adoption except in the case of new applications of already-diffused technologies. Consistent with the definitions of health care interventions provided by the Institute of Medicine and the Federal Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests, procedures, services and programs, and care delivery. Horizon scanning involves two processes. The first is identifying and monitoring new and evolving health care interventions that are purported to or may hold potential to diagnose, treat, or otherwise manage a particular condition or to improve care delivery for a variety of conditions. The second is analyzing the relevant health care context in which these new and evolving interventions exist to understand their potential impact on clinical care, the health care system, patient outcomes, and costs. It is NOT the goal of the AHRQ Healthcare Horizon Scanning System to make predictions on the future use and costs of any health care technology. Rather, the reports will help to inform and guide the planning and prioritization of research resources. This edition of the Status Update lists interventions that have been identified and are being monitored. The next edition will be published in 2–3 months. We welcome comments on the list, which may be sent by mail to the Task Order Officer named in this report to: Agency for Healthcare Research and Quality, 540 Gaither Road, Rockville, MD 20850, or by email to: [email protected]. Richard Kronick, Ph.D. David Meyers, M.D. Director Acting Director Agency for Healthcare Research and Quality Center for Evidence and Practice Improvement Agency for Healthcare Research and Quality Elise Berliner, Ph.D. Task Order Officer Center for Evidence and Practice Improvement Agency for Healthcare Research and Quality ii Contents Introduction ............................................................................................................................................................................. 1 Section 1. Currently Tracked Interventions: 498 Interventions .............................................................................................. 3 Table 1. AHRQ Priority Condition: 01 Arthritis and Nontraumatic Joint Disease: 10 Interventions ....................... 4 Table 2. AHRQ Priority Condition: 02 Cancer: 186 Interventions ........................................................................... 9 Table 3. AHRQ Priority Condition: 03 Cardiovascular Disease: 49 Interventions ............................................... 144 Table 4. AHRQ Priority Condition: 04 Dementia (including Alzheimer’s: 17 Interventions ............................... 180 Table 5. AHRQ Priority Condition: 05 Depression and Other Mental Health Disorders: 19 Interventions .......... 190 Table 6. AHRQ Priority Condition: 06 Developmental Delays, Attention-Deficit Hyperactivity Disorder, and Autism: 7 Interventions ......................................................................................................................... 200 Table 7. AHRQ Priority Condition: 07 Diabetes Mellitus: 14 Interventions ......................................................... 204 Table 8. AHRQ Priority Condition: 08 Functional Limitations and Disability: 98 Interventions ......................... 216 Table 9. AHRQ Priority Condition: 09 Infectious Disease, Including HIV-AIDS: 40 Interventions ................... 276 Table 10. AHRQ Priority Condition: 10 Obesity: 8 Interventions ........................................................................ 295 Table 11. AHRQ Priority Condition: 11 Peptic Ulcer Disease and Dyspepsia: 9 Interventions ........................... 300 Table 12. AHRQ Priority Condition: 12 Pregnancy, Including Preterm Birth: 4 Interventions ............................ 305 Table 13. AHRQ Priority Condition: 13 Pulmonary Disease, Asthma: 17 Interventions...................................... 307 Table 14. AHRQ Priority Condition: 14 Substance Abuse: 13 Interventions ....................................................... 315 Table 15. AHRQ Priority Condition: 15 Cross-Cutting: 7 Interventions .............................................................. 326 Section 2. Interventions Added Since Last Update: 108 Interventions .............................................................................. 330 Table 16. AHRQ Priority Condition: 01 Arthritis and Nontraumatic Joint Disease: 5 Interventions ................... 331 Table 17. AHRQ Priority Condition: 02 Cancer: 34 Interventions ....................................................................... 334 Table 18. AHRQ Priority Condition: 03 Cardiovascular Disease: 8 Interventions ............................................... 357 Table 19. AHRQ Priority Condition: 04 Dementia (including Alzheimer’s: 1 Intervention ................................. 361 Table 20. AHRQ Priority Condition: 05 Depression and Other Mental Health Disorders: 0 Interventions .......... 361 Table 21. AHRQ Priority Condition: 06 Developmental Delays, Attention-Deficit Hyperactivity Disorder, and Autism: 0 Interventions ......................................................................................................................... 361 Table 22. AHRQ Priority Condition: 07 Diabetes Mellitus: 3 Interventions......................................................... 362 Table 23. AHRQ Priority Condition: 08 Functional Limitations and Disability: 32 Interventions ....................... 364 Table 24. AHRQ Priority Condition: 09 Infectious Disease, Including HIV-AIDS: 14 Interventions ................. 387 Table 25. AHRQ Priority Condition: 10 Obesity: 0 Interventions ........................................................................ 394 Table 26. AHRQ Priority Condition: 11 Peptic Ulcer Disease and Dyspepsia: 0 Interventions