ANNUAL REPORT 2019 A YEAR OF TRANSFORMATION AND EXPANSION SAMUEL WAXMAN CANCER RESEARCH FOUNDATION ANNUAL REPORT 2019 TABLE OF CONTENTS Letter from SWCRF Leadership 1 A Year in Photos 2 In Historic Milestone for the SWCRF, 53 Scientists Funded 4 The SWCRF $32m Five-Year Campaign off to Good Start 5 New SWCRF Research Programs 6 The SWCRF Partners with Wiley for its First Aging and Cancer Journal 7 2019 Scientific Review and Breakthroughs Presentation 8 The SWCRF Spearheads The Development of an International Research Center 9 Meet the New SWCRF Board Members 10 Financial Statement 11 2019/2020 Donor Listings 12 The Samuel Waxman Cancer Research Foundation’s mission is to eradicate cancer by funding collaborative cross-institutional research to identify and correct abnormal gene function that causes cancer. This research is the basis for developing minimally toxic treatments for all patients with cancer. ANNUAL REPORT 2019 1 A YEAR OF TRANSFORMATION AND EXPANSION Dear Friend, 2019 was a historic and transformative year for cancer research. The Samuel Waxman Cancer Research Foundation (SWCRF) directed more than $2.2 million dollars of donor-raised funds to high-impact and collaborative research and launched two innovative research programs. We partnered with Wiley to inaugurate a first-ever peer-review journal, and we made progress in establishing an international research center. The journal and center will drive much-needed Michael Nierenberg science and thought leadership around aging and cancer. Chairman The discoveries reported by the SWCRF-funded scientists at our annual Scientific Review reinforced to us that our approach —funding novel ideas and scientists willing to collaborate with others outside of their labs—worked. Their research addressed 14 types of cancer and found new pathways for developing more targeted and effective treatments. Our relentless focus on why cancer starts in the first place leverages our research dollars to impact many types of cancers. We take collaboration seriously. That is why we partnered with The Alan B. Slifka Foundation and Israel Cancer Research Fund to establish the Max Ritvo, Alan Slifka and Desiree Dato Award for Fusion-Oncoprotein Cancers and Metastasis program. This program pairs a physician-scientist in the United States with a scientist in Samuel Waxman, M.D. Israel to tackle a deadly form of pediatric cancer and the leading cause of cancer Founder and CEO death: metastasis. We were delighted at the interest this international collaborative program generated among the research community. None of these achievements would have been possible without supporters like you. Together, we truly are making breakthroughs to tackle the world’s most prolific and deadly diseases. Thank you. With gratitude, William T. Sullivan Michael Nierenberg Samuel Waxman, M.D. William T. Sullivan Executive Director 2 ANNUAL REPORT 2019 MARCH 24 A YEAR IN PHOTOS Throughout the year, the SWCRF community gathered to advance cancer research and make memorable moments. Here are just a few. Courtesy of WPIX11 “Up Close with Marvin Scott” on PIX11 News featured Dr. Waxman for another appearance. Dr. Waxman spoke with Mr. Scott about cancer treatment advancements and dispelled myths and misinformation about this disease. MAY 1 MAY 5 MAY 14 Rob Rich SWCRF The SWCRF Associate Board raised SWCRF Iconic fashion designer Dennis Basso $30,000 for the SWCRF at a Havana- Cyclists braved pelting rain to “cycle presented an exclusive fashion show themed fundraiser. The Associate for a cure” in the TD Five Boro Bike Tour. to a sold-out crowd at the 6th Annual Board comprises young professionals The cyclists raised $20,000 for Collaborating for a Cure Ladies committed to ending cancer. This event the SWCRF. Luncheon. The event raised $45,000 to was their inaugural fundraiser. benefit the SWCRF research programs. JUNE 2-4 JUNE 24 Charles ManleyCharles Charles ManleyCharles The 37th Annual SWCRF Golf Tournament raised more than $225,000 More than 60 scientists and guests gathered for the two-day annual Scientific and honored sports radio personality Review. SWCRF-funded scientists presented their research findings to the SWCRF Ann Liguori for her long-standing cancer Scientific Advisory Board and science leadership. Immediately following, the research support. The tournament SWCRF presented its annual Breakthroughs symposium to highlight some of is the longest-running fundraiser for the research findings and provide foundation updates. More than 120 attended the SWCRF. More than 100 golfers Breakthroughs, including supporters, the board of directors, community participated in the tournament held at stakeholders, and press members. the Fresh Meadow Country Club in Lake Success, New York. ANNUAL REPORT 2019 3 JULY 11 JULY 13 NOVEMBER 3 SWCRF Members of Team Waxman ran 26.2 miles and raised $15,000 for the SWCRF Patrick McMullen Patrick at the TCS New York City Marathon. The SWCRF was an official charity partner of The 15th Annual Hamptons Happening the famous race, with more than 53,000 raised $450,000 for the SWCRF and runners crossing the finish line. honored TV chef Lidia Bastianich and generations of the Bastianich Family; Antonella Bertello, real estate DECEMBER 10 entrepreneur and owner of The Baker Courtesy of Nasdaq House 1650; restaurateur, Ian Duke; Dr. Waxman, supporters, and honorees and fashion designer, Nicole Miller. The of the Hamptons Happening, rang the “Tour de Cuisine” theme featured some Nasdaq Closing Bell. It was the fourth of the world’s most popular flavors consecutive year that the SWCRF under one tent at the Bridgehampton participated in the iconic bell-ringing property of Kenneth and Maria Fishel. ceremony. The event showcases the SWCRF to the world and Times Square. NOVEMBER 24 Courtesy Alan Rosmarin of NOVEMBER 21 Emmanuelle Passegué, Ph.D., a SWCRF- Funded scientist was honored with the annual William Dameshek Prize bestowed by the American Society of Hematology (ASH). Dr. Passegué, who directs the Stem Cell Initiative at Columbia University Herbert Irving Comprehensive Cancer Center, received her first grant from the SWCRF in 2019 Courtesy of ICRF as one of 7 grantees selected for the Dr. Samuel Waxman joined Riva Ariella foundation’s $1.4 million “Innovation Rob Rich Ritvo-Slifka, Ph.D., a SWCRF board Grant” program. She is studying Supporters of the 22nd Annual member and president of The Alan B. autophagy and hematopoietic stem Collaborating for a Cure Gala raised a Slifka Foundation, and Dr. Mark Israel, cell function in aging and leukemia. The record $6 million for the SWCRF. More president of the Israel Cancer Research prize recognizes her contributions to than 1,000 guests packed Cipriani Fund, to announce a new joint research advancing our understanding of the Wall Street to celebrate the 2019 gala program. The program highlighted in biology of blood-forming stem cells, honorees. They were Israeli-born this report paired scientists in the U.S. focusing on changes that happen to fashion designer, Kobi Halperin, Israeli- and Israel for collaborative research. stem cells in the contexts of myeloid born celebrity hairstylist, Valery Joseph, malignancies and aging. SWCRF and Marc Taub, owner of Taub Family scientific leaders, Dr. Jonathan Licht and Companies and a member of the SWCRF Dr. Alan Rosmarin, are pictured with Dr. Board of Directors. Guests enjoyed Passegué following the gourmet food, cocktails, a live auction, awards ceremony. and an exclusive performance by Lukas Nelson & the Promise of the Real. 4 ANNUAL REPORT 2019 SWCRF GRANTS BY PROGRAM IN HISTORIC 2019-2020 MILESTONE FOR THE SWCRF, 53 SCIENTISTS FUNDED Institute Without Walls Grants 38% Innovation Grants 25% The Samuel Waxman Cancer Research Foundation Aging and Cancer 21% (SWCRF) reached a historic milestone this year after Israel-U.S. Collaboration 9% funding 53 scientists, the most ever funded at any given time. Gladstein Bladder Cancer 7% A banner year of fundraising helped to buoy the SWCRF research programs including the launch of the Gary Gladstein Family Bladder Cancer Research Program and the Max Ritvo, Alan Slifka and Desiree Dato Award for Fusion-Oncoprotein Cancers and Metastasis research program in collaboration with The Alan B. Slifka SWCRF RESEARCH BY CANCER TYPE Foundation and the Israel Cancer Research Fund. 2019-2020 The SWCRF also completed its first year of the two-year Partnership for Aging and Cancer Research program in collaboration with the National Cancer Institute and National Institute on Aging. These programs added 21 more funded scientists to the nearly 30 funded within the SWCRF Institute Without Walls. This year, the SWCRF directed more than $2,200,000 in donor-supported funds to its research programs. “The generous support of the SWCRF during the past year enabled the foundation to expand its research Aging and Cancer I mmunology/Biology of Cancer programs that target the abnormal gene function that Bladder Lung causes cancer. Following the SWCRF tradition, the new B lood (Leukemia,Lymphoma, Ovarian research programs support research between scientists who collaborate across institutions, expertise and MDS, Multiple Myeloma and Pancreas countries,” said Dr. Samuel Waxman., founder and chief Pediatric Leukemia) Sarcoma executive officer of the SWCRF. Brain V arious (Colorectal, Liver, Neck) Breast ANNUAL REPORT 2019 5 THE SWCRF $32 MILLION FIVE-YEAR CAMPAIGN OFF TO GOOD START The Collaborating for a Cure Campaign—the Foundation’s Joseph Steffa, Howard Kurz, and Spencer Waxman, as well as first in 40 years—was launched in 2018. This five-year, Founder and CEO Samuel Waxman, Executive Director William $32 million campaign provides the resources to sustain the Sullivan and Jayme Koszyn of Koszyn & Company. They have level of excellence, integrity, and innovation that are the all worked tirelessly to execute the multiple activities of the hallmark of SWCRF’s approach to funding cancer research, as Campaign, and to lead us into the public phase, which will well as secures the SWCRF’s future as a financially sustainable, unfold in 2021.