NMS Labs CONFIDENTIAL 200 Welsh Road, Horsham, PA 19044-2208 Phone: (215) 657-4900 Fax: (215) 657-2972 e-mail: [email protected] Robert A. Middleberg, PhD, F-ABFT, DABCC-TC, Laboratory Director Demo Report Patient Name 2416U-POS Report Issued 03/14/2019 11:04 Patient ID 2416U-POS Last Report Issued 03/14/2019 11:04 Chain 19000451 Age Not Given DOB Not Given 88888 Gender Not Given Clinical Example Report Attn: Example Reports Workorder 19000451 200 Welsh Road Horsham, PA 19044 Received 03/14/2019 10:51 Sample ID 19000451-001 Collect Dt/Tm Not Given Matrix Urine Source Not Given Patient Name 2416U-POS Patient ID 2416U-POS Container Type Clear vial Approx Vol/Weight Not Given Receipt Notes None Entered Reporting Analysis and Comments Result Units Limit Notes 2416U Inhalants Metabolites Panel, Urine Analysis by Gas Chromatography (GC) o-Cresol 20 mg/L 0.50 ELEVATED Synonym(s): Toluene Metabolite The mean concentration in the urine of the general population is approximately 0.1 mg o-Cresol/L o-Cresol (Creatinine corrected) 4.0 mg/g Creat 0.10 ELEVATED Synonym(s): Toluene Metabolite Biological Exposure Index (ACGIH) for monitoring exposure to Toluene: 0.3 mg o-Cresol/g Creatinine measured in an end of shift urine specimen. Phenol - Total 20 mg/L 1.0 Less than 10 mg/L in unexposed individuals. Less than 30 mg/L when chronically exposed to 0.5 to 4.0 ppm Benzene in air. Average 200 mg/L during chronic exposure to 25 ppm Benzene in air. Phenol - Total (Creatinine corrected) 4.0 mg/g Creat 0.20 Results for sample 19000451-001 are continued on next page Page 1 of 3 NMS v.39.0 NMS Labs CONFIDENTIAL 200 Welsh Road, Horsham, PA 19044-2208 Phone: (215) 657-4900 Fax: (215) 657-2972 e-mail: [email protected] Robert A. Middleberg, PhD, F-ABFT, DABCC-TC, Laboratory Director Sample ID 19000451-001 Collect Dt/Tm Not Given Matrix Urine Source Not Given Patient Name 2416U-POS Patient ID 2416U-POS Reporting Analysis and Comments Result Units Limit Notes Biological Exposure Index (ACGIH): 250 mg Phenol/g Creatinine measured in an end of shift urine. Analysis by High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) Phenylglyoxylic Acid 0.050 g/L 0.0010 Synonym(s): Benzoylformic acid; Phenylglyoxylate; Styrene and Ethylbenzene Metabolite Phenylgloxylic acid is not usually detected in the non-exposed general population. Phenylglyoxylic Acid (Creatinine corrected) 0.010 g/g Creat 0.00020 Mandelic Acid 0.050 g/L 0.0050 Synonym(s): Mandelate; Styrene and Ethylbenzene Metabolite; alpha- Hydroxyphenylacetic acid The detection of significant amounts of mandelic acid in non-occupationally exposed populations is unlikely; however, a background level up to 0.005 g/L has been reported. Mandelic Acid (Creatinine corrected) 0.010 g/g Creat 0.0010 Mandelic Acid Plus Phenylglyoxylic Acid (Creatinine 0.020 g/g Creat corrected) Following exposure to styrene the ACGIH Biological Exposure Index (BEI) for mandelic acid plus phenylglyoxylic acid is 0.4 g/g creatinine measured in an end of shift urine specimen. Following exposure to ethylbenzene the ACGIH Biological Exposure Index (BEI) for mandelic acid plus phenylglyoxylic acid is 0.15 g/g creatinine measured in an end of shift urine specimen. Hippuric Acid 0.050 g/L 0.020 Synonym(s): Benzoylaminoacetic acid; Hippurate; N-Benzoylglycine; Toluene Metabolite Normal for unexposed populations is generally less than 1.6 g/L. Hippuric Acid (Creatinine corrected) 0.010 g/g Creat 0.0040 Normal for unexposed populations is generally less than 1.5 g/g creatinine. Results for sample 19000451-001 are continued on next page Page 2 of 3 NMS v.39.0 NMS Labs CONFIDENTIAL 200 Welsh Road, Horsham, PA 19044-2208 Phone: (215) 657-4900 Fax: (215) 657-2972 e-mail: [email protected] Robert A. Middleberg, PhD, F-ABFT, DABCC-TC, Laboratory Director Sample ID 19000451-001 Collect Dt/Tm Not Given Matrix Urine Source Not Given Patient Name 2416U-POS Patient ID 2416U-POS Reporting Analysis and Comments Result Units Limit Notes 2-Methylhippuric Acid 0.050 g/L 0.0050 Methylhippuric acids are not usually detected in the non-exposed general population. 2-Methylhippuric Acid (Creatinine corrected) 0.010 g/g Creat 0.0010 3- and 4-Methylhippuric Acid 0.050 g/L 0.0050 Methylhippuric acids are not usually detected in the non-exposed general population. 3- and 4-Methylhippuric Acid (Creatinine corrected) 0.010 g/g Creat 0.0010 Methylhippuric Acids - Total 0.10 g/L Synonym(s): Metabolites of Xylenes; Methylhippurates; Toluic acids Methylhippuric acids are usually not detected in the non-exposed general population. Methylhippuric Acids - Total (Creatinine corrected) 0.020 g/g Creat Following exposure to xylenes, the ACGIH Biological Exposure Index (BEI) for methylhippuric acids is 1.5 g/g creatinine measured in an end of shift urine specimen. Analysis by Colorimetry (C) Creatinine 5000 mg/L 100 U.S. Population (10th - 90th percentiles, median) All participants: 335 - 2370 mg/L, median 1180 (n=22,245) Males: 495 - 2540 mg/L, median 1370 (n=10,610) Females: 273 - 2170 mg/L, median 994 (n=11,635) 6022U Specific Gravity Confirmation, Urine Analysis by Refractometer (REF) Specific Gravity 1.100 ELEVATED Physiologic range: 1.010 - 1.030. Samples with specific gravity lower than 1.010 are too dilute and should be recollected. Page 3 of 3 NMS v.39.0.