Vol 58, No 2, June, 2019 UDK 61 ISSN 0365-4478 (Printed) ISSN 1821-2794 (Online) www.medfak.ni.ac.rs/amm Naučni časopis Medicinskog fakulteta Univerziteta u Nišu i Podružnice Srpskog lekarskog društva u Nišu Scientific Journal of the University of Niš Faculty of Medicine and the Department of the Serbian Medical Society in Niš Acta Medica Medianae Naučni časopis Medicinskog fakulteta Univerziteta u Nišu i Vol 58, No 2, June 2019 Podružnice Srpskog lekarskog društva u Nišu UDK 61 ISSN 0365-4478 (Printed version) Scientific journal of the University of Niš Faculty of Medicine and ISSN 1821-2794 (Online) the Department of the Serbian Medical Society in Niš http://www.medfak.ni.ac.rs/amm Izvršni urednik Executive Editor Uređivački savet Advisory Editors Prof. Boris Đinđić, MD, PhD (Niš, Serbia) Prof. Dobrila Stanković-Đorđević, MD, PhD (Niš, Serbia) Izvršni urednik za farmaciju Prof. Dragan Veselinović, MD, PhD (Niš, Serbia) Executive Editor for Pharmacy Uređivački odbor Prof. Andrija Šmelcerović, PhD (Niš, Serbia) Editorial Board Sekreterijat uređivačkog odbora Prof. Milan Višnjić, MD, PhD (Niš, Serbia) Editorial assisstants Prof. Dušica Pavlović, MD, PhD (Niš, Serbia) Prof. Miroslav Stojanović, MD, PhD (Niš, Serbia Jelena Milenković, MD, PhD (Niš, Serbia), sekretar (chief Prof. Dušan Sokolović, MD, PhD (Niš, Serbia) assistant) Assist. Prof. Voja Pavlović, MD, PhD (Niš, Serbia) Prof. Marija Daković-Bjelaković, MD, PhD (Niš, Serbia Assist. Prof. Zoran Bojanić, MD, PhD (Niš,Serbia) Prof. Dušanka Kitic, MD, PhD (Niš, Serbia) Assist. Prof. Jasmina Đorđević-Jocić, MD, PhD (Niš, Serbia) Prof. Ivan Micić, MD, PhD (Niš, Serbia) Assist. Prof.Jelena Lazarević, PhD (Niš, Serbia) Prof. Dušan Milisavljević, MD, PhD (Niš, Serbia) Dr Rade R. Babić, MD, PhD (Niš, Serbia) Prof. Biljana Đorđević, MD, PhD (Niš, Serbia) Assist. Prof. Nataša Milosavljević, PhD (Niš, Serbia) Prof. Maja Milojković, MD, PhD (Niš, Serbia) Nataša Bakić-Mirić, University lecturer of English, PhD (Niš, Prof. dr Eugene N. Myers (Pittsburgh, USA) Serbia) Prof. dr Helmut Roskamm (Bad Krozingen, Austria) Assist. Prof. Tomislav Kostić, MD, PhD (Niš, Serbia) Prof. dr Waldemar Kozuschek (Bochum, Germany) Danica Marković, MD (Niš, Serbia) Prof. dr Raimond Ardaillou (Paris, France) Slavica Stojnev, MD (Niš, Serbia) Prof. dr Milan Dimitrijević (Houston, USA) Denitsa Yancheva, PhD (Sofia, Bulgaria) Prof. dr Robin Leake (Glasgow, UK) Assist. Prof. Ivana Damnjanović, PharmD, PhD(Niš, Serbia) Academician Aleksej Prijmak (Moscow, Russia) Assist. Prof. Nikola Stefanović, PharmD, PhD (Niš, Serbia) Academician Mihail Pereljman (Moscow, Russia) Dane Krtinić, MD (Niš, Serbia) Prof. Miodrag Jevtić, MD, PhD (MMA, Belgrade, Serbia) Milovan Stojanović, MD (Niš, Serbia) Prof. dr Žernakova Nina Ivanovna (Belgorod, Russia) Assist. Milica Kostić, PharmD (Niš, Serbia) Academician Petrija Vasileva (Sofia, Bulgaria) Assist. Milica Milutinović, PharmD (Niš, Serbia) Prof. dr Badr Eldin Mostafa (Cairo, Egypt) Assist. Prof. Bojana Miladinović, PharmD, PhD (Niš, Serbia) Prof. dr Dan M. Fliss (Tel-Aviv, Israel) Assist. Dragan Zlatanović, MD, PhD (Niš, Serbia) Prof. Takanori Hattori, MD, PhD (Shiga, Japan) Assist. Bobana Milojković, MD, PhD (Niš, Serbia) Prof. Savevski Jordan, MD, PhD (Skopje, Macedonia) Assist. Prof. Tanja Džopalić, MD (Niš, Serbia) Prof. Davran Gaipov, PhD (Almaty, Kazakhstan) Dr Ana Spasić, PharmD (Niš, Serbia) Assoc. Prof. Ilko Getov, PhD (Sofia, Bulgaria) Dr Dušan Radomirović, MD (Niš, Serbia) Prof. Vladmila Bojanić, MD, PhD (Niš, Serbia) Dr Sonja Janković, MD (Niš, Serbia) Prof. Aleksandra Stankovic, MD, PhD (Niš, Serbia) Prof. Dragan Veselinović, MD, PhD (Niš, Serbia) Tehnička i internet obrada Academician. Milorad Mitković, MD, PhD (Niš, Serbia) Technical and Internet Editing Prof. Nebojša Đorđević, MD, PhD (Niš, Serbia) Topić Goran, BA Prof. Stojan Radić, MD, PhD (Niš, Serbia) Prof. Saša Živić, MD, PhD (Niš, Serbia) Lektor za engleski jezik Prof. Zorica Stanojević, MD, PhD (Niš, Serbia) Proofreading Prof. Dušica Stojanović, MD, PhD (Niš, Serbia) Nataša Šelmić-Milosavljević, Phd, Philology, English Prof. Stevo Najman, PhD (Niš, Serbia) language Prof. Zoran Radovanovic MD, PhD (Niš, Serbia) Bojana Marjanović, BA in English language and literature Lektori za srpski jezik Proofreading Ana Višnjić, BA in Serbian language and literature Neda Pavlović, Phd, Linguistics:Serbian language Acta Medica Medianae (UDK 61; ISSN 0365-4478 štampana verzija; ISSN 1821-2794 elektronska verzija) je zvanični časopis Medicinskog fakulteta Univerziteta u Nišu i Podružnice Srpskog lekarskog društva u Nišu pod pokroviteljstvom Ministarstva za nauku i tehnološki razvoj Republike Srbije. Časopis izlazi četiri puta godišnje od 1962 godine. Izdavač je Medicinski fakultet Univerziteta u Nišu, Bulevar dr Zorana Đinđića 81, 18000 Niš, Srbija. Sadržaj i celokupan tekst časopisa dostupan je na sajtu Medicinskog fakulteta http://www.medfak.ni.ac.rs/amm. Godišnja pretplata: za inostranstvo 60 USA dolara, za ustanove 2500 dinara i za pojedince 1500 dinara. Sredstva uplatiti na žiro račun Medicinskog fakulteta u Nišu br. 840-1681666-03, sa naznakom za Acta Medica Medianae. Uputstvo autorima se objavljuje u svakom broju, pri čemu je autor dužan da se pridržava navedenih uputstava prilikom predaje ruko- pisa. Radovi se mogu slati u elektronskom formatu na adresu: [email protected]. Naknada za štampanje rada iznosi 1000 dinara za autora, a 500 dinara za koautore, za svaki prihvaćeni rad. Acta Medica Medianae zadržava pravo dalje distribucije i štampanja radova. 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Press: “Galaksijanis”, Lukovo, Svrljig, Serbia Acta Medica Medianae is currently indexed in Index Copernicus, Serbian Citation Index, DOAJ and EBSCO Copyright © by University of Niš Faculty of Medicine Acta Medica Medianae Naučni časopis Medicinskog fakulteta Univerziteta u Nišu i Vol 58, No 2, June 2019 Podružnice Srpskog lekarskog društva u Nišu UDK 61 ISSN 0365-4478 (Printed version) Scientific journal of the University of Niš Faculty of Medicine and ISSN 1821-2794 (Online) the Department of the Serbian Medical Society in Niš http://www.medfak.ni.ac.rs/amm Autor slike na prednjoj stranici: Neda Pavlović Vol 58, No 2, June, 2019 INCREASED BLOOD PRESSURE DURING PUBERTY 5 Božidar Stojiljković, Ljubiša Lilić, Sladjana Milošević THE ROLE OF MAST CELLS IN CARBON TETRACHLORIDE INDUCED RAT SKELETAL MUSCLE TISSUE DAMAGE 11 Ljubiša M. Lilić, Dragan Toskić, Rade Ž. Stefanović, Branimir B. Mekić, Ivan R. Ilić, Nikola M. Stojanović INCIDENCE TREND OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE 16 Dejan Veljković, Zorana Deljanin PHYSICAL ACTIVITY AS AN IMPORTANT FACTOR FOR THE REDUCTION OF LIPID RISK FACTORS AT THE SECONDARY PREVENTION OF CORONARY HEART DISEASE IN MEN 22 Aleksandar Rajić, Vesko Milenković, Rade Stefanović, Milica Bojović, Sladjana Milošević, Jasmina Ranković, Branimir Mekić, Ljubiša Lilić, Lazar Toskić, Jadranka Kocić, Hadži Miloš Vidaković CARDIOVASCULAR RISK REDUCTION AND CORRECTION OF HYPERLIPIDEMIA IN PATIENTS AT PRIMARY PREVENTION THROUGH PHYSICAL ACTIVITY 27 Branimir Mekić, Dragan Toskić, Tatjana Popović-Ilić, Hadži Saša Ilić, Vesko Milenković, Aleksandar Rajić, Milica Bojović, Jasmina Ranković, Miroslav Živković, Hadži Miloš Vidaković CENTRAL CORNEAL THICKNESS MEASURED BY THE OCULYZER, BIOGRAPH, AND ULTRASOUND PACHYMETRY 33 Marko Zlatanović, Maja Živković, Aleksandra Hristov, Vesna Stojković, Saša Novak, Nevena Zlatanović, Mladen Brzaković THREE MONTH FOLLOW UP OF THE EFFECTS OF CONTINUOUS POSITIVE PRESSURE DURING SLEEP (CPAP) ON THE VALUE OF GLYCATED HEMOGLOBIN HBA1C AND GLYCOREGULATION IN OBESE DIABETIC PATIENTS WITH CONFIRMED SEVERE OPSTRUCTIVE SLEEP APNEA 38 Nikola Mladenović, Zoran Stamenković, Lidija Ristić, Dane Krtinić, Nemanja Petrović, Andrej Preveden, Bogdan Okiljević, Iva Binić, Miodrag Djordjević THE RELATIONSHIP BETWEEN BODY MASS INDEX AND THE QUALITY OF LIFE OF THE URBAN ADULT