Bachmair Lab Master’s position in plant molecular biology About the Bachmair lab Focus of the Bachmair lab lies on the biochemical and cell biological analysis of protein turnover driven by amino-terminal degradation signals. The biological context is how plants respond to environmental stimuli such as heat, flooding, or salt stress. Additional information can be found on the group page of the Bachmair lab. About the research project The applicant shall analyze protein turnover that depends on amino-terminal degradation signals. Firstly, expression of plant ubiquitin ligases via a synthetic biology approach in the budding yeast S. cerevisiae serves to elucidate turnover mechanisms. Secondly, expression vectors for so-called tandem fluorescent timer reporters shall be made and tested in plants. These vectors serve to investigate tissue- specificity and subcellular localization of turnover pathways. Candidates Successful candidates should have finished studies in Molecular Biology, Biochemistry or related (B. Sc.), and have 45 ECTS accomplished in the Master module. Interest in plant signal transduction and cellular homeostasis is advantageous. Duration: Ca. 12 months, starting Sep 2021 or later Payment: According to FWF payment scheme Contact: Univ.-Prof. Dr. Andreas Bachmair [email protected] Max Perutz Labs, Dept. of Biochemistry and Cell Biology, Univ. Wien Rm. 5110, Dr.-Bohr-Gasse 9, A-1030 Wien About the Max Perutz Labs The Max Perutz Labs are a research institute established by the University of Vienna and the Medical University of Vienna to provide an environment for excellent, internationally recognized research and education in the field of Molecular Biology. Dedicated to a mechanistic understanding of fundamental biomedical processes, scientists at the Max Perutz Labs aim to link breakthroughs in basic research to advances in human health. The Max Perutz Labs are located at the Vienna BioCenter, one of Europe’s hotspots for Life Sciences, and host around 50 research groups, involving more than 450 scientists and staff from 40 nations. MAX PERUTZ LABS A joint venture of Part of Vienna BioCenter (VBC) • Dr.-Bohr-Gasse 9 • 1030 Vienna Tel: +43 1 4277 24001 • [email protected] www.maxperutzlabs.ac.at.
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