Society for Biomaterials Annual Meeting and Exposition 2013 Biomaterials Revolution Transactions of the 37th Annual Meeting Volume XXXV Boston, Massachusetts, USA 10-13 April 2013 Volume 1 of 2 ISBN: 978-1-62748-128-1 ISSN: 1526-7547 Copyright and Disclaimer Society For Biomaterials Transactions of the 37th Annual Meeting Volume XXXV Published by: Society For Biomaterials 15000 Commerce Parkway, Suite C Mount Laurel, NJ 08054 (856)439-0826 Copyright © 2013 Society For Biomaterials, USA ISSN# 1526-7547 All rights reserved. No part of this publication may be reproduced in any form by Photostat, microfilm, retrieval system, or any other means, without written permission from the publisher. The materials published in this volume are not intended to be considered by the reader as statements of standards of care or definitions of the state of the art in patient care or applications of the scientific principles described in the contents. The statements of fact and opinions expressed are those of the respective authors who are identified in the abstracts. Publications of these materials by the Society For Biomaterials does not express or imply approval or agreement of the officers, staff, or agents of the Society with the items presented herein and should not be viewed by the reader as an endorsement thereof. Neither the Society For Biomaterials nor its agents are responsible for inaccuracies or omissions in this Publication. Every effort has been made to faithfully reproduce these Transactions as submitted. No responsibility is assumed by the Organizers for any injury and/or damage to persons or property as a matter of product liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in all sciences, we recommend that independent verification of the material presented should be made. This product was produced for the Society For Biomaterials by Omnipress. Duplication of this product and its content in print or digital form for the purpose of sharing with others is prohibited without permission from the Society For Biomaterials. In no event will Omnipress or its suppliers be liable for any consequential or incidental damages to your hardware or other software resulting from the installation and/or use of this product. No part of the product navigation and "Help" files may be reproduced or used without written permission from Omnipress. ©2012 Omnipress - All rights reserved. Table of Contents Oral CS1 Cardiovascular Biomaterials 1 Long Term in vivo Study of Rapidly Degradable Synthetic Arterial Grafts R. A. Allen, University of Pittsburgh, Pittsburgh, PA W. Wu, Qindu Hospital, Fourth Military Medical University, Xi'an, China M. Yao, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania D. Dutta, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, Pennsylvania X. Duan, University of Pittsburgh, Pittsburgh, Pennsylvania T. N. Bachman, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania H. C. Champion, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania D. B. Stolz, University of Pittsburgh, Pittsburgh, Pennsylvania A. M. Robertson, University of Pittsburgh, Pittsburgh, Pennsylvania K. Kim, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, Pennsylvania J. S. Isenberg, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Y. Wang, University of Pittsburgh, Pittsburgh, Pennsylvania 2 Bioactive anti-apoptotic coating: from 2D substrates to 3D commercial stent grafts for in vivo testing P. Lequoy, Ecole de Technologie Superieure, Montreal, QC, Canada M. Sbai, Ecole de Technologie Supérieure, Montreal, Québec, Canada B. Saoudi, Ecole Polytechnique de Montreal, Montreal, Québec, Canada A. Bertrand-Grenier, Universite de Montreal, Montreal, Québec, Canada M. Wertheimer, Ecole polytechnique de Montreal, Montreal, Québec, Canada G. Soulez, Universite de Montreal, Montreal, Québec, Canada S. Lerouge, Ecole de technologie superieure, Montreal, Québec, Canada 3 Catheter-deliverable, Thermal and pH Responsive Hydrogels for Delivery of Cardiac Progenitor Cells into Infarcted Hearts J. Guan, The Ohio State University, Columbus, OH 4 Pro-angiogenic and Anti-inflammatory Biomaterial Therapies for Peripheral Artery Disease A. L. Zachman, Vanderbilt University, Nashville, TN J. Ticker-Schwartz, Vanderbilt University, Nashville, Tennessee F. Shen, Vanderbilt University, Nashville, Tennessee S. Fitzpatrick, Vanderbilt University, Nashville, Tennessee M. Skala, Vanderbilt University, Nashville, Tennessee H. Sung, Vanderbilt University, Nashville, Tennessee 5 Stacked collagen film enabled engineered small vascular graft Y. Kim, University of Texas at Arlington, Arlington, TX S. Shah, University of Texas at Arlington, Arlington, Texas J. Ahmed, University of Texas at Arlington, Arlington, Texas 6 Effects Of Electrical Stimulation and Insulin-like Growth Factor On Heart Cells Cultured On A Microfabricated Degradable Elastomer H. Park, C.S. Draper Laboratory, Cambridge, MA B. L. Larson, MIT, Cambridge, Massachusetts M. E. Kolewe, MIT, Cambridge, Massachusetts G. Vunjak-Novakovic, Columbia University, New York, New York L. E. Freed, C.S. Draper Laboratory; MIT, Cambridge, Massachusetts 7 Mutli-Arm PEG Hydrogels Containing Collagen Sequence and Cell-Adhesive Sequence Support Enzyme Mediated Degradation and Endothelial Cell Proliferation D. R. Jones, Case Western Reserve University, Cleveland Heights, OH 8 An Endothelium Simulating Multifunctional Nanomatrix for Drug Eluting Stents H. Jun, University of Alabama at Birmingham, Birmingham, AL A. Andukuri, University of Alabama at Birmingham, Birmingham, Alabama Y. Sohn, Emory University, Atlanta, Georgia Y. Yoon, Emory University, Atlanta, Georgia B. Brott, University of Alabama at Birmingham, Birmingham, Alabama Drug Delivery1 9 Injectable Scaffolds with Degradable Calcium Alginate Beads as a Cell Delivery System for Tissue Repair R. Guo, Vanderbilt University, Nashville, TN C. L. Ward, United States Army Institute of Surgical Research, Fort Sam Houston, Texas S. A. Guelcher, Vanderbilt University, Nashville, Tennessee 10 Novel Sugar-Glass Nanoparticles system for Biomolecules Stabilization and Delivery in Tissue Engineering Applications j. Giri, Parffenbarg Research Center,, Gaithersburg, MD 11 A pro-healing polyHEMA scaffold as an antibiotic-releasing insert for a scleral bandage A. Galperin, University of Washington, Seattle, WA K. Smith, University of Washington, Seattle, Washington J. Bryers, University of Washington, Seattle, Washington T. Shen, University of Washington, Seattle, Washington B. Ratner, University of Washington, Seattle, Washington 12 Sequential drug delivery - in vitro and in vivo S. Sundararaj, University of Kentucky, Lexington, KY M. Thomas, University of Kentucky, Lexington, Kentucky M. Al-Sabbagh, University of Kentucky, Lexington, Kentucky T. Dziubla, University of Kentucky, Lexington, Kentucky D. Puleo, University of Kentucky, Lexington, Kentucky 13 Tunable Dual Growth Factor Delivery Using Multilayered Microparticles with Controllable Degradation Kinetics X. Yu, University of Wisconsin-Madison, Madison, WI 14 Development of a pH-responsive hydrogel network for the oral delivery of human growth hormone S. D. Steichen, The University of Texas at Austin, Austin, TX N. Peppas, The University of Texas at Austin, Austin, Texas 15 Self-Assembled Micellar Complex Comprised of Green Tea Catechin Derivatives for Protein Drug Delivery S. Tan, Institute of Bioengineering and Nanotechnology, Singapore, Singapore 16 Controlled Protein Release from Layer-by-Layer Coated Hydrogel Scaffolds for Nerve Repair D. A. Lynam, Michigan State University, East Lansing, MI D. Shahriari, Michigan State University, East Lansing, Michigan P. Angart, Michigan State University, East Lansing, Michigan K. Koffler, University of California-San Diego, La Jolla, California C. Chan, Michigan State University, East Lansing, Michigan P. Walton, Michigan State University, East Lansing, Michigan M. Tuszynski, University of California-San Diego, La Jolla, California J. Sakamoto, Michigan State University, East Lansing, Michigan Surface Characterization and Modification1 17 Nanofiber mediated osteoinduction through RhoA GTPase signaling T. Ozdemir, The Pennsylvania State University, University Park, PA 18 Nonfouling and Functionalizable Hydrogels based on Polyampholyte Chemistries M. T. Bernards, University of Missouri, Columbia, MO M. Schroeder, University of Missouri, Columbia, Missouri D. E. McGrath, University of Missouri, Columbia, Missouri K. M. Zurick, University of Missouri, Columbia, Missouri 19 Studying the Synergistic Effect of Coatings and Nitric Oxide release on Platelet Adsorption K. A. Amoako, University of Washington, Seattle, Seattle, WA 20 Surface Modification of a Poly(Glycolic-co-Lactic Acid) – Poly(DL-Lactide-co-Caprolactone) Small-Diameter Vascular Graft via CD34 Antibody Immobilization to Enhance Cell Attachment A. J. Melchiorri, University of Maryland, College Park, MD N. Hibino, Children's National Medical Center, District of Columbia, District of Columbia J. P. Fisher, University of Maryland, College Park, Maryland 21 Migrating versus Stationary Applied Pressure Changes Lubricity of Hydrogel Surfaces A. C. Dunn, University of Florida, Gainesville, FL J. Uruena, University of Florida, Gainesville, Florida T. E. Angelini, University of Florida, Gainesville, Florida W. Sawyer, University of