KRT72 Antibody Cat. No.: 60-728 KRT72 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine This KRT72 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 313-342 amino acids from the Central region of human KRT72. TESTED APPLICATIONS: WB APPLICATIONS: For WB starting dilution is: 1:1000 PREDICTED MOLECULAR 56 kDa WEIGHT: Properties This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification. CLONALITY: Polyclonal ISOTYPE: Rabbit Ig CONJUGATE: Unconjugated September 27, 2021 1 https://www.prosci-inc.com/krt72-antibody-60-728.html PHYSICAL STATE: Liquid BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide. CONCENTRATION: batch dependent Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Additional Info OFFICIAL SYMBOL: KRT72 Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root ALTERNATE NAMES: sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2 ACCESSION NO.: Q14CN4 PROTEIN GI NO.: 166218813 GENE ID: 140807 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and BACKGROUND: stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene. REFERENCES: 1) Bertheau, P., et al. PLoS Med.(3), E90 (2007) : 2) Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006) 3) Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003) 4) Porter, R.M., et al. Br. J. Dermatol. 145(4):558-568(2001) ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 27, 2021 2 https://www.prosci-inc.com/krt72-antibody-60-728.html.